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In Vitro and In Vivo Activities of Novel 6-Methylidene Penems as β-Lactamase Inhibitors

Antimicrobial Agents and Chemotherapy, 2004-12, Vol.48 (12), p.4589-4596

2004

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Syntheses and Pharmacokinetic Studies of Prodrug Esters for the Development of Oral Carbapenem, L-084

Journal of antibiotics, 2006-04, Vol.59 (4), p.241-247

2006

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Synthesis of New Chiral Sulfinyldiacetic Acid Derivatives and Attempt at Chemoselective Asymmetric Pummerer Reaction

Chemical and Pharmaceutical Bulletin, 2002, Vol.50(4), pp.558-562

2002

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5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of β-lactamases

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (4), p.1890-1902

2008

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Structure-Activity Relationship of 6-Methylidene Penems Bearing 6,5 Bicyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors: Evidence for 1,4-Thiazepine Intermediates with C7 R Stereochemistry by Computational Methods

Journal of medicinal chemistry, 2006-07, Vol.49 (15), p.4623-4637

2006

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Targeting Val 216 in Class A β-Lactamases with Tricyclic 6-Methylidene Penems

ChemMedChem, 2008-11, Vol.3 (11), p.1658-1661

2008

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On the Absolute Configuration in 1,4-Dihydrothiazepine Covalent Complexes Derived from Inhibition of Class A and C β-Lactamases with 6-Methylidene Penems

ChemMedChem, 2007-12, Vol.2 (12), p.1713-1716

2007

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Erythro-Selective Aldol Reaction of Tricarbonyl(η6-o-trialkylsilylbenzaldehyde)chromium(0) Complexes with Cyclic Ketene Silyl Acetals

Chemical and Pharmaceutical Bulletin, 1991/11/25, Vol.39(11), pp.2863-2866

1991

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In Vitro and In Vivo Activities of Novel 6-Methylidene Penems as β-Lactamase Inhibitors

Syntheses and Pharmacokinetic Studies of Prodrug Esters for the Development of Oral Carbapenem, L-084

Synthesis of New Chiral Sulfinyldiacetic Acid Derivatives and Attempt at Chemoselective Asymmetric Pummerer Reaction

5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of β-lactamases

Structure-Activity Relationship of 6-Methylidene Penems Bearing 6,5 Bicyclic Heterocycles as Broad-Spectrum β-Lactamase Inhibitors: Evidence for 1,4-Thiazepine Intermediates with C7 R Stereochemistry by Computational Methods

Targeting Val 216 in Class A β-Lactamases with Tricyclic 6-Methylidene Penems

On the Absolute Configuration in 1,4-Dihydrothiazepine Covalent Complexes Derived from Inhibition of Class A and C β-Lactamases with 6-Methylidene Penems

Erythro-Selective Aldol Reaction of Tricarbonyl(η6-o-trialkylsilylbenzaldehyde)chromium(0) Complexes with Cyclic Ketene Silyl Acetals

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