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The ERK1 2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

Oncogene, 2007-05, Vol.26 (22), p.3227-3239

2007

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RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth

Oncogene, 2013-06, Vol.32 (24), p.2917-2926

2013

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ERK1/2-induced phosphorylation of R-Ras GTPases stimulates their oncogenic potential

Oncogene, 2016-10, Vol.35 (43), p.5692-5698

2016

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Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA

Genes & development, 2001-10, Vol.15 (20), p.2702-2719

2001

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Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

Genes & development, 2013-04, Vol.27 (8), p.900-915

2013

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Coordinate, biphasic activation of p44 mitogen-activated protein kinase and S6 kinase by growth factors in hamster fibroblasts. Evidence for thrombin-induced signals different from phosphoinositide turnover and adenylylcyclase inhibition

The Journal of biological chemistry, 1992-07, Vol.267 (19), p.13369-13375

1992

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The IKK-related kinases： from innate immunity to oncogenesis

Cell research, 2008-09, Vol.18 (9), p.889-899

2008

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Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.19683-19690

2004

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Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

BMJ (Online), 2016-04, Vol.353, p.i1753

2016

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An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

EMBO reports, 2003-10, Vol.4 (10), p.964-968

2003

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N-Terminal Ubiquitination of Extracellular Signal-Regulated Kinase 3 and p21 Directs Their Degradation by the Proteasome

Molecular and Cellular Biology, 2004-07, Vol.24 (14), p.6140-6150

2004

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Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells

Molecular pharmacology, 1995-10, Vol.48 (4), p.582

1995

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Towards the development of chromone-based MEK1/2 modulators

European journal of medicinal chemistry, 2014-10, Vol.85, p.127-138

2014

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Rapid Turnover of Extracellular Signal-Regulated Kinase 3 by the Ubiquitin-Proteasome Pathway Defines a Novel Paradigm of Mitogen-Activated Protein Kinase Regulation during Cellular Differentiation

Molecular and Cellular Biology, 2003-07, Vol.23 (13), p.4542-4558

2003

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MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo

Circulation (New York, N.Y.), 2004-04, Vol.109 (16), p.1938-1941

2004

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Mutational analysis of the interaction between CD4 and class II MHC: Class II antigens contact CD4 on a surface opposite the gp120-binding site

Cell, 1991-09, Vol.66 (5), p.1037-1049

1991

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p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

The EMBO journal, 2001-12, Vol.20 (23), p.6672-6682

2001

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Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI

Journal of the American Society of Nephrology, 2020-11, Vol.31 (11), p.2725-2735

2020

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Nuclear Export of ERK3 by a CRM1-dependent Mechanism Regulates Its Inhibitory Action on Cell Cycle Progression

The Journal of biological chemistry, 2003-10, Vol.278 (43), p.42615-42624

2003

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Rho Family GTPases Are Required for Activation of Jak/STAT Signaling by G Protein-Coupled Receptors

Molecular and Cellular Biology, 2003-02, Vol.23 (4), p.1316-1333

2003

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Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway

The EMBO journal, 2004-12, Vol.23 (24), p.4780-4791

2004

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Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis

Oncogene, 2000-07, Vol.19 (31), p.3460-3469

2000

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Insulin induces Ca2+ influx into isolated rat hepatocyte couplets

American journal of physiology: Gastrointestinal and liver physiology, 1997-06, Vol.272 (6), p.G1425-G1432

1997

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Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms

The Journal of cell biology, 2000-02, Vol.148 (3), p.543-556

2000

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The ERK1 2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth

ERK1/2-induced phosphorylation of R-Ras GTPases stimulates their oncogenic potential

Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA

Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

Coordinate, biphasic activation of p44 mitogen-activated protein kinase and S6 kinase by growth factors in hamster fibroblasts. Evidence for thrombin-induced signals different from phosphoinositide turnover and adenylylcyclase inhibition

The IKK-related kinases： from innate immunity to oncogenesis

Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

N-Terminal Ubiquitination of Extracellular Signal-Regulated Kinase 3 and p21 Directs Their Degradation by the Proteasome

Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells

Towards the development of chromone-based MEK1/2 modulators

Rapid Turnover of Extracellular Signal-Regulated Kinase 3 by the Ubiquitin-Proteasome Pathway Defines a Novel Paradigm of Mitogen-Activated Protein Kinase Regulation during Cellular Differentiation

MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo

Mutational analysis of the interaction between CD4 and class II MHC: Class II antigens contact CD4 on a surface opposite the gp120-binding site

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI

Nuclear Export of ERK3 by a CRM1-dependent Mechanism Regulates Its Inhibitory Action on Cell Cycle Progression

Rho Family GTPases Are Required for Activation of Jak/STAT Signaling by G Protein-Coupled Receptors

Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway

Inflammation, Hyperglycemia, and Adverse Outcomes in Individuals With Diabetes Mellitus Hospitalized for COVID-19

Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis

Insulin induces Ca2+ influx into isolated rat hepatocyte couplets

Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms

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