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Structural and Quantum Chemical Studies of 8-Aryl-sulfanyl Adenine Class Hsp90 Inhibitors

Journal of medicinal chemistry, 2006-08, Vol.49 (16), p.4953-4960

2006

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Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer

Nature chemical biology, 2007-08, Vol.3 (8), p.498-507

2007

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Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines

Bioorganic & medicinal chemistry letters, 2009-01, Vol.19 (2), p.415-417

2009

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Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

ACS chemical biology, 2014-08, Vol.9 (8), p.1698-1705

2014

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Synthesis of a red-shifted fluorescence polarization probe for Hsp90

Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (17), p.4515-4518

2006

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Design of a fluorescence polarization assay platform for the study of human Hsp70

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (13), p.3749-3751

2008

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Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5‑(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1188-1207

2014

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Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5‑(Phenylthio)pyrimidines, 2‑(Pyridin-3-ylthio)pyrimidines, and 3‑(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1208-1224

2014

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Discovery and development of purine-scaffold Hsp90 inhibitors

Expert opinion on drug discovery, 2008-01, Vol.3 (1), p.99-114

2008

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Design of a flexible cell-based assay for the evaluation of heat shock protein 70 expression modulators

Assay and drug development technologies, 2011-06, Vol.9 (3), p.236-246

2011

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Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

Chemistry & biology, 2013-12, Vol.20 (12), p.1469-1480

2013

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Diversity analyses of bacterial symbionts in four Sclerodermus (Hymenoptera: Bethylidae) parasitic wasps, the dominant biological control agents of wood-boring beetles in China

Frontiers in cellular and infection microbiology, 2024-07, Vol.14, p.1439476

2024

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Vegetation response to climate zone dynamics and its impacts on surface soil water content and albedo in China

The Science of the total environment, 2020-12, Vol.747, p.141537-141537, Article 141537

2020

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Hazardous areas determination of coal spontaneous combustion in shallow-buried gobs of coal seam group: a physical simulation experimental study

Environmental earth sciences, 2019, Vol.78 (1), p.1-11, Article 39

2019

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Observing and Modeling the Isotopic Evolution of Snow Meltwater on the Southeastern Tibetan Plateau

Water resources research, 2020-09, Vol.56 (9), p.n/a

2020

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Standardization of monitoring data reassesses spatial distribution of aquatic microplastics concentrations worldwide

Water research (Oxford), 2024-05, Vol.254, p.121356-121356, Article 121356

2024

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Numerical evaluation of spinal reconstruction using a 3D printed vertebral body replacement implant: effects of material anisotropy

Frontiers in bioengineering and biotechnology, 2024-06, Vol.12, p.1305837

2024

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Analysis of the relationship between water and energy in China based on a multi-regional input-output method

Journal of environmental management, 2022-05, Vol.309, p.114680-114680, Article 114680

2022

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ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome

BMC psychiatry, 2024-05, Vol.24 (1), p.335-335, Article 335

2024

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NDRG2 gene expression pattern in ovarian cancer and its specific roles in inhibiting cancer cell proliferation and suppressing cancer cell apoptosis

Journal of ovarian research, 2020-04, Vol.13 (1), p.48-48, Article 48

2020

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Cerebrospinal fluid mesencephalic astrocyte-derived neurotrophic factor: A moderating effect on sleep time and cognitive function

Journal of psychiatric research, 2024-08, Vol.176, p.33-39

2024

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KCNQ1OT1 promotes ovarian cancer progression via modulating MIR‐142‐5p/CAPN10 axis

Molecular genetics & genomic medicine, 2020-02, Vol.8 (2), p.e1077-n/a

2020

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Celecoxib prevents pressure overload‐induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress

Journal of cellular and molecular medicine, 2016-01, Vol.20 (1), p.116-127

2016

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Association of Prolonged Disease Duration and TG/HDL-C Ratio in Accelerating Atherosclerosis in Patients with Takayasu's Arteritis

Clinical and applied thrombosis/hemostasis, 2022, Vol.28, p.107602962211212-10760296221121297

2022

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New insights into trace elements in the water cycle of a karst-dominated glacierized region, southeast Tibetan Plateau

The Science of the total environment, 2021-01, Vol.751, p.141725-141725, Article 141725

2021

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Structural and Quantum Chemical Studies of 8-Aryl-sulfanyl Adenine Class Hsp90 Inhibitors

Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer

Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines

Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

Synthesis of a red-shifted fluorescence polarization probe for Hsp90

Design of a fluorescence polarization assay platform for the study of human Hsp70

Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5‑(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

Heat Shock Protein 70 Inhibitors. 2. 2,5′-Thiodipyrimidines, 5‑(Phenylthio)pyrimidines, 2‑(Pyridin-3-ylthio)pyrimidines, and 3‑(Phenylthio)pyridines as Reversible Binders to an Allosteric Site on Heat Shock Protein 70

Discovery and development of purine-scaffold Hsp90 inhibitors

Design of a flexible cell-based assay for the evaluation of heat shock protein 70 expression modulators

Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

Diversity analyses of bacterial symbionts in four Sclerodermus (Hymenoptera: Bethylidae) parasitic wasps, the dominant biological control agents of wood-boring beetles in China

Vegetation response to climate zone dynamics and its impacts on surface soil water content and albedo in China

Hazardous areas determination of coal spontaneous combustion in shallow-buried gobs of coal seam group: a physical simulation experimental study

Observing and Modeling the Isotopic Evolution of Snow Meltwater on the Southeastern Tibetan Plateau

Standardization of monitoring data reassesses spatial distribution of aquatic microplastics concentrations worldwide

Numerical evaluation of spinal reconstruction using a 3D printed vertebral body replacement implant: effects of material anisotropy

Analysis of the relationship between water and energy in China based on a multi-regional input-output method

ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome

NDRG2 gene expression pattern in ovarian cancer and its specific roles in inhibiting cancer cell proliferation and suppressing cancer cell apoptosis

Cerebrospinal fluid mesencephalic astrocyte-derived neurotrophic factor: A moderating effect on sleep time and cognitive function

KCNQ1OT1 promotes ovarian cancer progression via modulating MIR‐142‐5p/CAPN10 axis

Celecoxib prevents pressure overload‐induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress

Association of Prolonged Disease Duration and TG/HDL-C Ratio in Accelerating Atherosclerosis in Patients with Takayasu's Arteritis

New insights into trace elements in the water cycle of a karst-dominated glacierized region, southeast Tibetan Plateau

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