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New drugs in acute myeloid leukemia

Annals of oncology, 2016-05, Vol.27 (5), p.770-778

2016

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Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells

Leukemia, 2017-09, Vol.31 (9), p.1951-1961

2017

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BET protein bromodomain inhibitor-based combinations are highly active against post-myeloproliferative neoplasm secondary AML cells

Leukemia, 2017-03, Vol.31 (3), p.678-687

2017

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A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome

Leukemia, 2016-02, Vol.30 (2), p.268-273

2016

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Characteristics, outcomes, prognostic factors and treatment of patients with T-cell prolymphocytic leukemia (T-PLL)

Annals of oncology, 2017-07, Vol.28 (7), p.1554-1559

2017

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Achievement of a negative minimal residual disease state after hypomethylating agent therapy in older patients with AML reduces the risk of relapse

Leukemia, 2018-01, Vol.32 (1), p.241-244

2018

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Prognostic significance of 11q23 aberrations in adult acute myeloid leukemia and the role of allogeneic stem cell transplantation

Leukemia, 2013-04, Vol.27 (4), p.836-842

2013

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The combination of hyper-CVAD plus nelarabine as frontline therapy in adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma: MD Anderson Cancer Center experience

Leukemia, 2014-04, Vol.28 (4), p.973-975

2014

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A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials

Leukemia, 2017-02, Vol.31 (2), p.318-324

2017

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A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials

Leukemia, 2017-07, Vol.31 (7), p.1659-1659

2017

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Bendamustine added to allogeneic conditioning improves long-term outcomes in patients with CLL

Bone marrow transplantation (Basingstoke), 2017-01, Vol.52 (1), p.28-33

2017

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Phase I/II multicenter study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD4877 in patients with refractory acute myeloid leukemia

Investigational new drugs, 2012-06, Vol.30 (3), p.1107-1115

2012

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Clinical, pharmacokinetic and pharmacodynamic data for the MEK1/2 inhibitor pimasertib in patients with advanced hematologic malignancies

Blood cancer journal (New York), 2015-12, Vol.5 (12), p.e375-e375

2015

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Final report of a phase II study of imatinib mesylate with hyper-CVAD for the front-line treatment of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

Haematologica (Roma), 2015-05, Vol.100 (5), p.653-661

2015

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Idarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study

The Lancet. Haematology, 2019-09, Vol.6 (9), p.e480-e488

2019

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Ruxolitinib in combination with lenalidomide as therapy for patients with myelofibrosis

Haematologica (Roma), 2015-08, Vol.100 (8), p.1058

2015

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Differential Coupling of Serotonin 5‐HT1A and 5‐HT1B Receptors to Activation of ERK2 and Inhibition of Adenylyl Cyclase in Transfected CHO Cells

Journal of neurochemistry, 1999-07, Vol.73 (1), p.162-168

1999

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Midostaurin In Acute Myeloid Leukemia: An Evidence-Based Review And Patient Selection

Cancer management and research, 2019-01, Vol.11, p.8817-8828

2019

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Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia

Haematologica (Roma), 2015-07, Vol.100 (7), p.927-934

2015

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Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies

Haematologica (Roma), 2013-02, Vol.98 (2), p.217-221

2013

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Activating internal tandem duplication mutations of the fms-like tyrosine kinase-3 (FLT3-ITD) at complete response and relapse in patients with acute myeloid leukemia

Haematologica (Roma), 2012-08, Vol.97 (8), p.1242-1245

2012

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Hypocellular acute myeloid leukemia in adults: analysis of the clinical outcome of 123 patients

Haematologica (Roma), 2012-02, Vol.97 (2), p.235-240

2012

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Peripheral Blasts on Day 21 of Induction Chemotherapy in a Patient With Core Binding Factor Acute Myeloid Leukemia: More Than Meets the Eye

Clinical lymphoma, myeloma and leukemia, 2010-08, Vol.10 (4), p.301-302

2010

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Actor-network theory to understand, track and succeed in a sustainable innovation development process

Journal of cleaner production, 2019-07, Vol.225, p.524-540

Aka, Kadia Georges

2019

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Acute myeloid leukemia: current progress and future directions

Blood cancer journal (New York), 2021-02, Vol.11 (2), p.41-25, Article 41

2021

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New drugs in acute myeloid leukemia

Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells

BET protein bromodomain inhibitor-based combinations are highly active against post-myeloproliferative neoplasm secondary AML cells

A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome

Characteristics, outcomes, prognostic factors and treatment of patients with T-cell prolymphocytic leukemia (T-PLL)

Achievement of a negative minimal residual disease state after hypomethylating agent therapy in older patients with AML reduces the risk of relapse

Prognostic significance of 11q23 aberrations in adult acute myeloid leukemia and the role of allogeneic stem cell transplantation

The combination of hyper-CVAD plus nelarabine as frontline therapy in adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma: MD Anderson Cancer Center experience

A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials

A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials

Bendamustine added to allogeneic conditioning improves long-term outcomes in patients with CLL

Phase I/II multicenter study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD4877 in patients with refractory acute myeloid leukemia

Clinical, pharmacokinetic and pharmacodynamic data for the MEK1/2 inhibitor pimasertib in patients with advanced hematologic malignancies

Final report of a phase II study of imatinib mesylate with hyper-CVAD for the front-line treatment of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

Idarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study

Ruxolitinib in combination with lenalidomide as therapy for patients with myelofibrosis

Differential Coupling of Serotonin 5‐HT1A and 5‐HT1B Receptors to Activation of ERK2 and Inhibition of Adenylyl Cyclase in Transfected CHO Cells

Midostaurin In Acute Myeloid Leukemia: An Evidence-Based Review And Patient Selection

Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia

Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies

Activating internal tandem duplication mutations of the fms-like tyrosine kinase-3 (FLT3-ITD) at complete response and relapse in patients with acute myeloid leukemia

Hypocellular acute myeloid leukemia in adults: analysis of the clinical outcome of 123 patients

Peripheral Blasts on Day 21 of Induction Chemotherapy in a Patient With Core Binding Factor Acute Myeloid Leukemia: More Than Meets the Eye

Actor-network theory to understand, track and succeed in a sustainable innovation development process

Acute myeloid leukemia: current progress and future directions

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