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An α-π transition in S6 shapes the conformational cycle of the bacterial sodium channel NavAb

The Journal of general physiology, 2023-02, Vol.155 (2), p.1

2023

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Climatic controls on the global distribution, abundance, and species richness of mangrove forests

Ecological monographs, 2017-05, Vol.87 (2), p.341-359

2017

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tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut

Nucleic acids research, 2024-01, Vol.52 (2), p.513

2024

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Elephants in the Dark: Insights and Incongruities in Pentameric Ligand-gated Ion Channel Models

Journal of molecular biology, 2021-08, Vol.433 (17), p.167128-167128, Article 167128

Howard, Rebecca J.

2021

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Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels

Cell reports (Cambridge), 2018-04, Vol.23 (4), p.993-1004

2018

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Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport

Biochimica et biophysica acta. Biomembranes, 2018-04, Vol.1860 (4), p.927-942

2018

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Molecular Dynamics Simulations of Ion Channels

Trends in biochemical sciences (Amsterdam. Regular ed.), 2021-07, Vol.46 (7), p.621-622

2021

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Molecular mechanism for the dual alcohol modulation of Cys-loop receptors

PLoS computational biology, 2012-10, Vol.8 (10), p.e1002710-e1002710

2012

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The Structure of the APPBP1-UBA3-NEDD8-ATP Complex Reveals the Basis for Selective Ubiquitin-like Protein Activation by an E1

Molecular cell, 2003-12, Vol.12 (6), p.1427-1437

2003

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Inhibition versus Potentiation of Ligand-Gated Ion Channels Can Be Altered by a Single Mutation that Moves Ligands between Intra- and Intersubunit Sites

Structure (London), 2013-08, Vol.21 (8), p.1307-1316

2013

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Structure and dynamics of differential ligand binding in the human ρ-type GABAA receptor

Neuron (Cambridge, Mass.), 2023-11, Vol.111 (21), p.3450-3464.e5

2023

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Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM

eLife, 2024-01, Vol.12, p.2023

2024

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Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium

Biochimica et biophysica acta. Biomembranes, 2022-10, Vol.1864 (10), p.183994-183994, Article 183994

2022

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Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site

The Journal of biological chemistry, 2021-08, Vol.297 (2), p.100899, Article 100899

2021

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Plant Community Establishment in a Coastal Marsh Restored Using Sediment Additions

Wetlands (Wilmington, N.C.), 2020-08, Vol.40 (4), p.877-892

2020

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Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization

ACS chemical neuroscience, 2023-03, Vol.14 (6), p.1156-1165

2023

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Growth of Common Brackish Marsh Macrophytes Under Altered Hydrologic and Salinity Regimes

Wetlands (Wilmington, N.C.), 2016-02, Vol.36 (1), p.11-20

2016

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Functional and structural insights into activation of TRPV2 by weak acids

The EMBO journal, 2024-04, Vol.43 (11), p.2264-2290

2024

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Sharing Data from Molecular Simulations

Journal of chemical information and modeling, 2019-10, Vol.59 (10), p.4093-4099

2019

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Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics

Pharmacological reviews, 2014-04, Vol.66 (2), p.396-412

2014

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Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids

Protein engineering, design and selection, 2024-01, Vol.37

2024

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Linear and nonlinear effects of temperature and precipitation on ecosystem properties in tidal saline wetlands

Ecosphere (Washington, D.C), 2017-10, Vol.8 (10), p.n/a

2017

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Soil surface elevation dynamics in a mangrove-to-marsh ecotone characterized by vegetation shifts

Hydrobiologia, 2020-02, Vol.847 (4), p.1087-1106

2020

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A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy

The Journal of biological chemistry, 2021-12, Vol.297 (6), p.101355-101355, Article 101355

2021

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Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC)

The Journal of biological chemistry, 2013-03, Vol.288 (12), p.8355-8364

2013

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An α-π transition in S6 shapes the conformational cycle of the bacterial sodium channel NavAb

Climatic controls on the global distribution, abundance, and species richness of mangrove forests

tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut

Elephants in the Dark: Insights and Incongruities in Pentameric Ligand-gated Ion Channel Models

Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels

Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport

Molecular Dynamics Simulations of Ion Channels

Molecular mechanism for the dual alcohol modulation of Cys-loop receptors

The Structure of the APPBP1-UBA3-NEDD8-ATP Complex Reveals the Basis for Selective Ubiquitin-like Protein Activation by an E1

Inhibition versus Potentiation of Ligand-Gated Ion Channels Can Be Altered by a Single Mutation that Moves Ligands between Intra- and Intersubunit Sites

Structure and dynamics of differential ligand binding in the human ρ-type GABAA receptor

Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM

Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium

Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site

Plant Community Establishment in a Coastal Marsh Restored Using Sediment Additions

Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization

Growth of Common Brackish Marsh Macrophytes Under Altered Hydrologic and Salinity Regimes

Functional and structural insights into activation of TRPV2 by weak acids

Sharing Data from Molecular Simulations

Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics

Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids

Linear and nonlinear effects of temperature and precipitation on ecosystem properties in tidal saline wetlands

Soil surface elevation dynamics in a mangrove-to-marsh ecotone characterized by vegetation shifts

A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy

Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC)

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