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The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

Nature reviews. Drug discovery, 2014-01, Vol.13 (1), p.63-79

2014

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Transduction of mechanical and cytoskeletal cues by YAP and TAZ

Nature reviews. Molecular cell biology, 2012-09, Vol.13 (9), p.591-600

2012

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Hippo signaling: growth control and beyond

Development (Cambridge), 2011-01, Vol.138 (1), p.9-22

2011

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The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Journal of hepatology, 2015-09, Vol.63 (3), p.679-688

2015

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Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling

PLoS genetics, 2015-02, Vol.11 (2), p.e1004994

2015

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Modulating F-actin organization induces organ growth by affecting the Hippo pathway

The EMBO journal, 2011-06, Vol.30 (12), p.2325-2335

2011

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Initiation of hepatic stellate cell activation extends into chronic liver disease

Cell death & disease, 2021-11, Vol.12 (12), p.1110-1110, Article 1110

2021

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Regulation of the Hippo pathway by cell architecture and mechanical signals

Seminars in cell & developmental biology, 2012-09, Vol.23 (7), p.803-811

2012

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An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model

Current biology, 2016-08, Vol.26 (16), p.2101-2113

2016

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Genes & development, 2007-11, Vol.21 (21), p.2747-2761

2007

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Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis

Gastroenterology (New York, N.Y. 1943), 2021-02, Vol.160 (3), p.847-862

2021

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The bantam MicroRNA Is a Target of the Hippo Tumor-Suppressor Pathway

Current biology, 2006-10, Vol.16 (19), p.1895-1904

2006

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YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role

International journal of molecular sciences, 2019-02, Vol.20 (3), p.638

2019

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Shared enhancer gene regulatory networks between wound and oncogenic programs

eLife, 2023-05, Vol.12

2023

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A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models

Molecular cancer therapeutics, 2024-01, Vol.23 (1), p.3-13

2024

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The Fat Cadherin Acts through the Hippo Tumor-Suppressor Pathway to Regulate Tissue Size

Current biology, 2006-11, Vol.16 (21), p.2090-2100

2006

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Discovering the Hippo pathway protein-protein interactome

Cell research, 2014-02, Vol.24 (2), p.137-138

2014

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Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

Nature cell biology, 2003-10, Vol.5 (10), p.914-920

2003

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A Mouse Model of Cholangiocarcinoma Uncovers a Role for Tensin‐4 in Tumor Progression

Hepatology (Baltimore, Md.), 2021-09, Vol.74 (3), p.1445-1460

2021

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Cell Junctions in Hippo Signaling

Cold Spring Harbor perspectives in biology, 2018-05, Vol.10 (5), p.a028753

2018

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Mask Is Required for the Activity of the Hippo Pathway Effector Yki/YAP

Current biology, 2013-02, Vol.23 (3), p.229-235

2013

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Dynamic rewiring of the Drosophila retinal determination network switches its function from selector to differentiation

PLoS genetics, 2013-08, Vol.9 (8), p.e1003731-e1003731

2013

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The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth

Journal of cell science, 2009-07, Vol.122 (Pt 14), p.2351-2359

2009

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Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila

Development (Cambridge), 2002-12, Vol.129 (24), p.5719-5730

2002

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Hippo-YAP/TAZ signalling in organ regeneration and regenerative medicine

Nature reviews. Molecular cell biology, 2019-04, Vol.20 (4), p.211-226

2019

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The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

Hippo signaling: growth control and beyond

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling

Modulating F-actin organization induces organ growth by affecting the Hippo pathway

Initiation of hepatic stellate cell activation extends into chronic liver disease

Regulation of the Hippo pathway by cell architecture and mechanical signals

An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Regeneration Defects in Yap and Taz Mutant Mouse Livers Are Caused by Bile Duct Disruption and Cholestasis

The bantam MicroRNA Is a Target of the Hippo Tumor-Suppressor Pathway

YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role

Shared enhancer gene regulatory networks between wound and oncogenic programs

A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models

The Fat Cadherin Acts through the Hippo Tumor-Suppressor Pathway to Regulate Tissue Size

Discovering the Hippo pathway protein-protein interactome

Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

A Mouse Model of Cholangiocarcinoma Uncovers a Role for Tensin‐4 in Tumor Progression

Cell Junctions in Hippo Signaling

Mask Is Required for the Activity of the Hippo Pathway Effector Yki/YAP

Dynamic rewiring of the Drosophila retinal determination network switches its function from selector to differentiation

The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth

Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila

Hippo-YAP/TAZ signalling in organ regeneration and regenerative medicine

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