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Optimization of expression yield in a stable cell line expressing a novel mutated chimeric tissue plasminogen activator (mt-PA)

Brazilian Journal of Pharmaceutical Sciences, 2022-01, Vol.58

2022

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DARPin Ec1-LMWP protein scaffold in targeted delivery of siRNA molecules through EpCAM cancer stem cell marker

Molecular biology reports, 2020-10, Vol.47 (10), p.7323-7331

2020

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The Epigenetic Regulation of Blinatumomab Gene Expression: Tumor Cell-dependent T cell Response against Lymphoma Cells and Cytotoxic Activity

International journal of molecular and cellular medicine, 2019, Vol.8 (1), p.55-66

2019

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Combined TGE-SGE Expression of Novel PAI-1-Resistant t-PA in CHO DG44 Cells Using Orbitally Shaking Disposable Bioreactors

Journal of Microbiology and Biotechnology, 2011, 21(12), , pp.1299-1305

2011

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Production and characterization of a camelid single domain anti-CD22 antibody conjugated to DM1

Molecular and cellular biochemistry, 2024-03, Vol.479 (3), p.579-590

2024

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Targeted integration in CHO cells using CRIS-PITCh/Bxb1 recombinase–mediated cassette exchange hybrid system

Applied microbiology and biotechnology, 2023-02, Vol.107 (2-3), p.769-783

2023

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CHO cell engineering via targeted integration of circular miR-21 decoy using CRISPR/RMCE hybrid system

Applied microbiology and biotechnology, 2024-12, Vol.108 (1), p.434, Article 434

2024

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Anti-CD19 Monoclonal Antibodies: a New Approach to Lymphoma Therapy

International journal of molecular and cellular medicine, 2015-01, Vol.4 (3), p.143-151

2015

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Targeted integration into pseudo attP sites of CHO cells using CRISPR/Cas9

Journal of biotechnology, 2021-08, Vol.337, p.1-7

2021

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A novel variant of t-PA resistant to plasminogen activator inhibitor-1; expression in CHO cells based on In Silico experiments

BMB Reports, 2011, 44(1), , pp.34-39

2011

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Efficient site-specific integration in CHO-K1 cells using CRISPR/Cas9-modified donors

Molecular biology reports, 2023-07, Vol.50 (7), p.5889-5899

2023

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Rapid characterization of the CHO platform cell line and identification of pseudo attP sites for PhiC31 integrase

Protein expression and purification, 2017-12, Vol.140, p.60-64

2017

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CRISPR‐interceded CHO cell line development approaches

Biotechnology and bioengineering, 2023-04, Vol.120 (4), p.865-902

2023

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Evaluating the expression profile and stability of different UCOE containing vector combinations in mAb-producing CHO cells

BMC biotechnology, 2017-02, Vol.17 (1), p.18-18, Article 18

2017

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Anti-Aβ-scFv-loaded polymeric nano-micelles with enhanced plasma stability

Journal of pharmacy and pharmacology, 2021-03, Vol.73 (4), p.460-472

2021

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Novel trastuzumab‐DM1 conjugate: Synthesis and bio‐evaluation

Journal of cellular physiology, 2019-10, Vol.234 (10), p.18206-18213

2019

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Evaluating the efficiency of phiC31 integrase-mediated monoclonal antibody expression in CHO cells

Biotechnology progress, 2016-11, Vol.32 (6), p.1570-1576

2016

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Bacterial production and biophysical characterization of a hard-to-fold scFv against myeloid leukemia cell surface marker, IL-1RAP

Molecular biology reports, 2023-02, Vol.50 (2), p.1191-1202

2023

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Cloning, expression and characterization of a HER2-alpha luffin fusion protein in Escherichia coli

Preparative biochemistry & biotechnology, 2019-09, Vol.49 (8), p.759-766

2019

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Construction of a Mammalian IRES-based Expression Vector to Amplify a Bispecific Antibody; Blinatumomab

Iranian journal of pharmaceutical research : IJPR, 2019-01, Vol.18 (4), p.2117-2123

2019

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PhiC31 integrase can improve the efficiency of different construct designs for monoclonal antibody expression in CHO cells

Protein expression and purification, 2017-06, Vol.134, p.89-95

2017

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Cloning and soluble expression of mature α-luffin from Luffa cylindrica in E. coli using SUMO fusion protein

Turkish journal of biology, 2018-01, Vol.42 (1), p.23-32

2018

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Optimization of EnBase Fed-Batch Cultivation to Improve Soluble Fraction Ratio of α-Luffin Ribosome Inactivating Protein

Iranian journal of biotechnology, 2018-04, Vol.16 (1), p.49-59

2018

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Proteomics investigation of molecular mechanisms affected by EnBase culture system in anti-VEGF fab fragment producing E. coli BL21 (DE3)

Preparative biochemistry & biotechnology, 2019-01, Vol.49 (1), p.48-57

2019

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A comparative study of the bispecific monoclonal antibody, blinatumomab expression in CHO cells and E. coli

Preparative biochemistry & biotechnology, 2018-11, Vol.48 (10), p.961-967

2018

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Optimization of expression yield in a stable cell line expressing a novel mutated chimeric tissue plasminogen activator (mt-PA)

DARPin Ec1-LMWP protein scaffold in targeted delivery of siRNA molecules through EpCAM cancer stem cell marker

The Epigenetic Regulation of Blinatumomab Gene Expression: Tumor Cell-dependent T cell Response against Lymphoma Cells and Cytotoxic Activity

Combined TGE-SGE Expression of Novel PAI-1-Resistant t-PA in CHO DG44 Cells Using Orbitally Shaking Disposable Bioreactors

Production and characterization of a camelid single domain anti-CD22 antibody conjugated to DM1

Targeted integration in CHO cells using CRIS-PITCh/Bxb1 recombinase–mediated cassette exchange hybrid system

CHO cell engineering via targeted integration of circular miR-21 decoy using CRISPR/RMCE hybrid system

Anti-CD19 Monoclonal Antibodies: a New Approach to Lymphoma Therapy

Targeted integration into pseudo attP sites of CHO cells using CRISPR/Cas9

A novel variant of t-PA resistant to plasminogen activator inhibitor-1; expression in CHO cells based on In Silico experiments

Efficient site-specific integration in CHO-K1 cells using CRISPR/Cas9-modified donors

Rapid characterization of the CHO platform cell line and identification of pseudo attP sites for PhiC31 integrase

CRISPR‐interceded CHO cell line development approaches

Evaluating the expression profile and stability of different UCOE containing vector combinations in mAb-producing CHO cells

Anti-Aβ-scFv-loaded polymeric nano-micelles with enhanced plasma stability

Novel trastuzumab‐DM1 conjugate: Synthesis and bio‐evaluation

Evaluating the efficiency of phiC31 integrase-mediated monoclonal antibody expression in CHO cells

Bacterial production and biophysical characterization of a hard-to-fold scFv against myeloid leukemia cell surface marker, IL-1RAP

Cloning, expression and characterization of a HER2-alpha luffin fusion protein in Escherichia coli

Construction of a Mammalian IRES-based Expression Vector to Amplify a Bispecific Antibody; Blinatumomab

PhiC31 integrase can improve the efficiency of different construct designs for monoclonal antibody expression in CHO cells

Cloning and soluble expression of mature α-luffin from Luffa cylindrica in E. coli using SUMO fusion protein

Optimization of EnBase Fed-Batch Cultivation to Improve Soluble Fraction Ratio of α-Luffin Ribosome Inactivating Protein

Proteomics investigation of molecular mechanisms affected by EnBase culture system in anti-VEGF fab fragment producing E. coli BL21 (DE3)

A comparative study of the bispecific monoclonal antibody, blinatumomab expression in CHO cells and E. coli

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