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ACE and LRPAP1 Insertion-Deletion Polymorphisms in a Northern Ivory Coast Population

Human biology, 2007-12, Vol.79 (6), p.699-706

2007

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AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity

Cancer research (Chicago, Ill.), 2004-07, Vol.64 (14), p.4931-4941

2004

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Tyrosine kinase inhibitors: From rational design to clinical trials

Medicinal research reviews, 2001-11, Vol.21 (6), p.499-512

2001

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Erythrocyte polymorphisms in five ethnic groups of Northern Côte d'Ivoire

International journal of immunogenetics, 2009-06, Vol.36 (3), p.189-191

2009

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Potent Antagonists of the SH2 Domain of Grb2: Optimization of the X+1 Position of 3-Amino-Z-Tyr(PO3H2)-X+1-Asn-NH2

Journal of medicinal chemistry, 1998-05, Vol.41 (11), p.1741-1744

1998

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Protein kinases as targets for anticancer agents: from inhibitors to useful drugs

Pharmacology & therapeutics (Oxford), 2002-02, Vol.93 (2), p.79-98

2002

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Structural basis for specificity of GRB2-SH2 revealed by a novel ligand binding mode

Nature structural biology, 1996-07, Vol.3 (7), p.586-589

1996

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COL1A2 gene deletion polymorphism in an Italian and an Ivorian populations

Russian journal of genetics, 2009-07, Vol.45 (7), p.857-860

2009

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In vitro trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors

Antimicrobial Agents and Chemotherapy, 1996-06, Vol.40 (6), p.1442-1447

1996

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Selective GRB2 SH2 inhibitors as anti‐Ras therapy

International journal of cancer, 1999-10, Vol.83 (2), p.235-241

1999

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Synthesis and biological evaluation of highly potent analogues of epothilones B and D

Bioorganic & medicinal chemistry letters, 2000-12, Vol.10 (24), p.2765-2768

2000

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Effect of Potent and Selective Inhibitors of the Grb2 SH2 Domain on Cell Motility

The Journal of biological chemistry, 1999-08, Vol.274 (33), p.23311-23315

1999

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Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands

Journal of molecular biology, 1998-06, Vol.279 (4), p.1013-1022

1998

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Discovery of 3-Aminobenzyloxycarbonyl as an N-Terminal Group Conferring High Affinity to the Minimal Phosphopeptide Sequence Recognized by the Grb2-SH2 Domain

Journal of medicinal chemistry, 1997-10, Vol.40 (22), p.3551-3556

1997

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Highly potent inhibitors of the Grb2-SH2 domain

Bioorganic & medicinal chemistry letters, 1999-01, Vol.9 (2), p.221-226

1999

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Modelling study of protein kinase inhibitors: binding mode of staurosporine and origin of the selectivity of CGP 52411

Journal of computer-aided molecular design, 1995-12, Vol.9 (6), p.465-472

1995

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Structure-based design of a non-peptidic antagonist of the SH2 domain of GRB2

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (14), p.1973-1978

1999

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Convergent synthesis of potent peptide inhibitors of the Grb2-SH2 domain by palladium catalyzed coupling of a terminal alkyne

Bioorganic & medicinal chemistry letters, 2001-05, Vol.11 (9), p.1201-1203

2001

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Dual Specificity of Src Homology 2 Domains for Phosphotyrosine Peptide Ligands

Biochemistry (Easton), 1997-05, Vol.36 (19), p.5712-5718

1997

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Inhibitory activity and selectivity of staurosporine derivatives towards protein kinase C

Bioorganic & medicinal chemistry letters, 1994-02, Vol.4 (3), p.399-404

1994

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Phenylamino-Pyrimidine (PAP) Derivatives: A New Class of Potent and Selective Inhibitors of Protein Kinase C (PKC)

Archiv der Pharmazie (Weinheim), 1996-07, Vol.329 (7), p.371-376

1996

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Structure-based design of peptidomimetic ligands of the Grb2-SH2 domain

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (20), p.2865-2870

1998

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Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 1

Bioorganic & medicinal chemistry letters, 2000-10, Vol.10 (20), p.2337-2341

2000

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S-Adenosylmethionine decarboxylase inhibitors: new aryl and heteroaryl analogs of methylglyoxal bis(guanylhydrazone)

Journal of medicinal chemistry, 1993, Vol.36 (1), p.46-54

1993

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Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2

Bioorganic & medicinal chemistry letters, 2000-10, Vol.10 (20), p.2343-2346

2000

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ACE and LRPAP1 Insertion-Deletion Polymorphisms in a Northern Ivory Coast Population

AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity

Tyrosine kinase inhibitors: From rational design to clinical trials

Erythrocyte polymorphisms in five ethnic groups of Northern Côte d'Ivoire

Potent Antagonists of the SH2 Domain of Grb2: Optimization of the X+1 Position of 3-Amino-Z-Tyr(PO3H2)-X+1-Asn-NH2

Protein kinases as targets for anticancer agents: from inhibitors to useful drugs

Structural basis for specificity of GRB2-SH2 revealed by a novel ligand binding mode

COL1A2 gene deletion polymorphism in an Italian and an Ivorian populations

In vitro trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors

Selective GRB2 SH2 inhibitors as anti‐Ras therapy

Synthesis and biological evaluation of highly potent analogues of epothilones B and D

Effect of Potent and Selective Inhibitors of the Grb2 SH2 Domain on Cell Motility

Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands

Discovery of 3-Aminobenzyloxycarbonyl as an N-Terminal Group Conferring High Affinity to the Minimal Phosphopeptide Sequence Recognized by the Grb2-SH2 Domain

Highly potent inhibitors of the Grb2-SH2 domain

Modelling study of protein kinase inhibitors: binding mode of staurosporine and origin of the selectivity of CGP 52411

Structure-based design of a non-peptidic antagonist of the SH2 domain of GRB2

Convergent synthesis of potent peptide inhibitors of the Grb2-SH2 domain by palladium catalyzed coupling of a terminal alkyne

Dual Specificity of Src Homology 2 Domains for Phosphotyrosine Peptide Ligands

Inhibitory activity and selectivity of staurosporine derivatives towards protein kinase C

Phenylamino-Pyrimidine (PAP) Derivatives: A New Class of Potent and Selective Inhibitors of Protein Kinase C (PKC)

Structure-based design of peptidomimetic ligands of the Grb2-SH2 domain

Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 1

S-Adenosylmethionine decarboxylase inhibitors: new aryl and heteroaryl analogs of methylglyoxal bis(guanylhydrazone)

Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2

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