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Screening antimicrobial peptides and probiotics using multiple deep learning and directed evolution strategies

Acta pharmaceutica Sinica. B, 2024-08, Vol.14 (8), p.3476-3492

2024

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Hydrogen sulfide upregulated lncRNA CasC7 to reduce neuronal cell apoptosis in spinal cord ischemia-reperfusion injury rat

Biomedicine & pharmacotherapy, 2018-02, Vol.98, p.856-862

2018

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SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models

Acta pharmacologica Sinica, 2018-02, Vol.39 (2), p.243-250

2018

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Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures

Drug design, development and therapy, 2021-01, Vol.15, p.4503-4525

2021

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Bone Tissue Engineering in the Treatment of Bone Defects

Pharmaceuticals (Basel, Switzerland), 2022-07, Vol.15 (7), p.879

2022

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Susceptibility-diffusion mismatch correlated with leptomeningeal collateralization in large vessel occlusion stroke

Journal of international medical research, 2021-05, Vol.49 (5), p.30006052110131-3000605211013179

2021

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Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52

Acta pharmacologica Sinica, 2021-04, Vol.42 (4), p.633-640

2021

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Enhanced bone regeneration of the silk fibroin electrospun scaffolds through the modification of the graphene oxide functionalized by BMP-2 peptide

International journal of nanomedicine, 2019-01, Vol.14, p.733-751

2019

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The regulation of cellular apoptosis by the ROS-triggered PERK/EIF2α/chop pathway plays a vital role in bisphenol A-induced male reproductive toxicity

Toxicology and applied pharmacology, 2017-01, Vol.314, p.98-108

2017

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Protective effects of Lizhong decoction on ulcerative colitis in mice by suppressing inflammation and ameliorating gut barrier

Journal of ethnopharmacology, 2020-09, Vol.259, p.112919, Article 112919

2020

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Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway

Acta pharmacologica Sinica, 2021-01, Vol.42 (1), p.108-114

2021

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Effects of Banxia Baizhu Tianma Decoction in alleviating atherosclerosis based on the regulation of perivascular adipose

Journal of ethnopharmacology, 2024-03, Vol.322, p.117575-117575, Article 117575

2024

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Polysaccharides From Chrysanthemum morifolium Ramat Ameliorate Colitis Rats via Regulation of the Metabolic Profiling and NF-κ B/TLR4 and IL-6/JAK2/STAT3 Signaling Pathways

Frontiers in pharmacology, 2018-07, Vol.9, p.746-746

2018

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Fabrication and Evaluation of a Xenogeneic Decellularized Nerve-Derived Material: Preclinical Studies of a New Strategy for Nerve Repair

Neurotherapeutics, 2020-01, Vol.17 (1), p.356-370

2020

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Dbl family RhoGEFs in cancer: different roles and targeting strategies

Biochemical pharmacology, 2024-05, Vol.223, p.116141, Article 116141

2024

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Hesperetin derivative-16 attenuates CCl4-induced inflammation and liver fibrosis by activating AMPK/SIRT3 pathway

European journal of pharmacology, 2022-01, Vol.915, p.174530, Article 174530

2022

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Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia

Biomedicine & pharmacotherapy, 2023-12, Vol.169, p.115905-115905, Article 115905

2023

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Delivery vehicle of muscle-derived irisin based on silk/calcium silicate/sodium alginate composite scaffold for bone regeneration

International journal of nanomedicine, 2019-01, Vol.14, p.1451-1467

2019

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Natural products as potential lead compounds to develop new antiviral drugs over the past decade

European journal of medicinal chemistry, 2023-11, Vol.260, p.115726, Article 115726

2023

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Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity

Acta pharmacologica Sinica, 2020-05, Vol.41 (5), p.698-705

2020

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Discovery of novel nucleoside derivatives as selective lysine acetyltransferase p300 inhibitors for cancer therapy

Bioorganic & medicinal chemistry letters, 2024-05, Vol.104, p.129742-129742, Article 129742

2024

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Efficacy of Aeschynomene indica L. leaves for wound healing and isolation of active constituent

Journal of ethnopharmacology, 2019-01, Vol.228, p.156-163

2019

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Investigation of the material basis and mechanism of Lizhong decoction in ameliorating ulcerative colitis based on spectrum-effect relationship and network pharmacology

Journal of ethnopharmacology, 2024-04, Vol.323, p.117666-117666, Article 117666

2024

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Sanguinarine Attenuates Collagen-Induced Platelet Activation and Thrombus Formation

Biomedicines, 2021-04, Vol.9 (5), p.444

2021

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Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors

Bioorganic & medicinal chemistry, 2022-04, Vol.59, p.116686-116686, Article 116686

2022

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Screening antimicrobial peptides and probiotics using multiple deep learning and directed evolution strategies

Hydrogen sulfide upregulated lncRNA CasC7 to reduce neuronal cell apoptosis in spinal cord ischemia-reperfusion injury rat

SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models

Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures

Bone Tissue Engineering in the Treatment of Bone Defects

Susceptibility-diffusion mismatch correlated with leptomeningeal collateralization in large vessel occlusion stroke

Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52

Enhanced bone regeneration of the silk fibroin electrospun scaffolds through the modification of the graphene oxide functionalized by BMP-2 peptide

The regulation of cellular apoptosis by the ROS-triggered PERK/EIF2α/chop pathway plays a vital role in bisphenol A-induced male reproductive toxicity

Protective effects of Lizhong decoction on ulcerative colitis in mice by suppressing inflammation and ameliorating gut barrier

Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway

Effects of Banxia Baizhu Tianma Decoction in alleviating atherosclerosis based on the regulation of perivascular adipose

Polysaccharides From Chrysanthemum morifolium Ramat Ameliorate Colitis Rats via Regulation of the Metabolic Profiling and NF-κ B/TLR4 and IL-6/JAK2/STAT3 Signaling Pathways

Fabrication and Evaluation of a Xenogeneic Decellularized Nerve-Derived Material: Preclinical Studies of a New Strategy for Nerve Repair

Dbl family RhoGEFs in cancer: different roles and targeting strategies

Hesperetin derivative-16 attenuates CCl4-induced inflammation and liver fibrosis by activating AMPK/SIRT3 pathway

Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia

Delivery vehicle of muscle-derived irisin based on silk/calcium silicate/sodium alginate composite scaffold for bone regeneration

Natural products as potential lead compounds to develop new antiviral drugs over the past decade

Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity

Discovery of novel nucleoside derivatives as selective lysine acetyltransferase p300 inhibitors for cancer therapy

Efficacy of Aeschynomene indica L. leaves for wound healing and isolation of active constituent

Investigation of the material basis and mechanism of Lizhong decoction in ameliorating ulcerative colitis based on spectrum-effect relationship and network pharmacology

Sanguinarine Attenuates Collagen-Induced Platelet Activation and Thrombus Formation

Discovery of novel 2,8-diazaspiro[4.5]decan-1-one derivatives as potent RIPK1 kinase inhibitors

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