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Bioequivalence Between Generic and Branded Lamotrigine in People With Epilepsy: The EQUIGEN Randomized Clinical Trial

JAMA neurology, 2017-08, Vol.74 (8), p.919

2017

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Pharmacokinetics of lamotrigine and its metabolite N‐2‐glucuronide: Influence of polymorphism of UDP‐glucuronosyltransferases and drug transporters

British journal of clinical pharmacology, 2016-08, Vol.82 (2), p.399-411

2016

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Dose-dependent effect of lamotrigine on quetiapine serum concentration in patients using instant release tablets

European journal of clinical pharmacology, 2024-06, Vol.80 (6), p.839-845

2024

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UGT2B10 is the Major UDP-Glucuronosyltransferase 2B Isoform Involved in the Metabolism of Lamotrigine and is Implicated in the Drug-Drug Interaction with Valproic Acid

The AAPS journal, 2024-09, Vol.26 (6), p.107, Article 107

2024

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Optimization of nanostructured lipid carriers of lamotrigine for brain delivery: in vitro characterization and in vivo efficacy in epilepsy

Expert opinion on drug delivery, 2015-02, Vol.12 (2), p.181-194

2015

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Direct nose-to-brain delivery of lamotrigine following intranasal administration to mice

International journal of pharmaceutics, 2015-07, Vol.490 (1-2), p.39-46

2015

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Population pharmacokinetics of lamotrigine co-administered with valproic acid in Chinese epileptic children using nonlinear mixed effects modeling

European journal of clinical pharmacology, 2018-05, Vol.74 (5), p.583-591

2018

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A pharmacological overview of lamotrigine for the treatment of epilepsy

Expert review of clinical pharmacology, 2016-12, Vol.9 (12), p.1533-1546

2016

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Correlation of the UGT1A4 gene polymorphism with serum concentration and therapeutic efficacy of lamotrigine in Han Chinese of Northern China

European journal of clinical pharmacology, 2014-08, Vol.70 (8), p.941-946

2014

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Extended-release drug formulations for the treatment of epilepsy

Expert opinion on pharmacotherapy, 2018-06, Vol.19 (8), p.843-850

2018

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The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy

Epilepsy research, 2011-06, Vol.95 (1), p.1-8

2011

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A rapid and simple HPLC–MS/MS method for the simultaneous quantification of valproic acid and its five metabolites in human plasma and application to study pharmacokinetic interaction in Chinese epilepsy patients

Journal of pharmaceutical and biomedical analysis, 2018-02, Vol.149, p.448-456

2018

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Influence of valproic acid concentration and polymorphism of UGT1A43, UGT2B7 -161C > T and UGT2B72 on serum concentration of lamotrigine in Chinese epileptic children

European journal of clinical pharmacology, 2015-11, Vol.71 (11), p.1341-1347

2015

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Lamotrigine in breast milk and nursing infants: determination of exposure

Pediatrics (Evanston), 2008-07, Vol.122 (1), p.e223-e231

2008

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Enhanced brain delivery of lamotrigine with Pluronic(®) P123-based nanocarrier

International journal of nanomedicine, 2014, Vol.9 (Issue 1), p.3923-3935

2014

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Paracetamol decreases steady‐state exposure to lamotrigine by induction of glucuronidation in healthy subjects

British journal of clinical pharmacology, 2016-04, Vol.81 (4), p.735-741

2016

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Lamotrigine is a substrate for OCT1 in brain endothelial cells

Biochemical pharmacology, 2012-03, Vol.83 (6), p.805-814

2012

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An easy-to-use liquid chromatography assay for the analysis of lamotrigine in rat plasma and brain samples using microextraction by packed sorbent: Application to a pharmacokinetic study

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-11, Vol.1035, p.67-75

2016

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Population pharmacokinetic models of lamotrigine in different age groups of Chinese children with epilepsy

European journal of clinical pharmacology, 2017-04, Vol.73 (4), p.445-453

2017

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Use of Therapeutic Drug Monitoring, Electronic Health Record Data, and Pharmacokinetic Modeling to Determine the Therapeutic Index of Phenytoin and Lamotrigine

Therapeutic drug monitoring, 2016-12, Vol.38 (6), p.728-737

2016

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Influence of the UGT2B7 -161C>T polymorphism on the population pharmacokinetics of lamotrigine in Thai patients

European journal of clinical pharmacology, 2013-06, Vol.69 (6), p.1285-1291

2013

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Prospectively assessed changes in lamotrigine-concentration in women with epilepsy during pregnancy, lactation and the neonatal period

Epilepsy research, 2009-07, Vol.85 (1), p.60-64

2009

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Factors that influence the pharmacokinetics of lamotrigine in Japanese patients with epilepsy

European journal of clinical pharmacology, 2016-05, Vol.72 (5), p.555-562

2016

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Effects of WIN 55,212-2 mesylate on the anticonvulsant action of lamotrigine, oxcarbazepine, pregabalin and topiramate against maximal electroshock-induced seizures in mice

European journal of pharmacology, 2013-11, Vol.720 (1-3), p.247-254

2013

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Bioequivalence Between Generic and Branded Lamotrigine in People With Epilepsy: The EQUIGEN Randomized Clinical Trial

Pharmacokinetics of lamotrigine and its metabolite N‐2‐glucuronide: Influence of polymorphism of UDP‐glucuronosyltransferases and drug transporters

Dose-dependent effect of lamotrigine on quetiapine serum concentration in patients using instant release tablets

UGT2B10 is the Major UDP-Glucuronosyltransferase 2B Isoform Involved in the Metabolism of Lamotrigine and is Implicated in the Drug-Drug Interaction with Valproic Acid

Optimization of nanostructured lipid carriers of lamotrigine for brain delivery: in vitro characterization and in vivo efficacy in epilepsy

Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society

Direct nose-to-brain delivery of lamotrigine following intranasal administration to mice

Population pharmacokinetics of lamotrigine co-administered with valproic acid in Chinese epileptic children using nonlinear mixed effects modeling

A pharmacological overview of lamotrigine for the treatment of epilepsy

Correlation of the UGT1A4 gene polymorphism with serum concentration and therapeutic efficacy of lamotrigine in Han Chinese of Northern China

Extended-release drug formulations for the treatment of epilepsy

The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy

A rapid and simple HPLC–MS/MS method for the simultaneous quantification of valproic acid and its five metabolites in human plasma and application to study pharmacokinetic interaction in Chinese epilepsy patients

Influence of valproic acid concentration and polymorphism of UGT1A43, UGT2B7 -161C > T and UGT2B72 on serum concentration of lamotrigine in Chinese epileptic children

Lamotrigine in breast milk and nursing infants: determination of exposure

Enhanced brain delivery of lamotrigine with Pluronic(®) P123-based nanocarrier

Paracetamol decreases steady‐state exposure to lamotrigine by induction of glucuronidation in healthy subjects

Lamotrigine is a substrate for OCT1 in brain endothelial cells

An easy-to-use liquid chromatography assay for the analysis of lamotrigine in rat plasma and brain samples using microextraction by packed sorbent: Application to a pharmacokinetic study

Population pharmacokinetic models of lamotrigine in different age groups of Chinese children with epilepsy

Use of Therapeutic Drug Monitoring, Electronic Health Record Data, and Pharmacokinetic Modeling to Determine the Therapeutic Index of Phenytoin and Lamotrigine

Influence of the UGT2B7 -161C>T polymorphism on the population pharmacokinetics of lamotrigine in Thai patients

Prospectively assessed changes in lamotrigine-concentration in women with epilepsy during pregnancy, lactation and the neonatal period

Factors that influence the pharmacokinetics of lamotrigine in Japanese patients with epilepsy

Effects of WIN 55,212-2 mesylate on the anticonvulsant action of lamotrigine, oxcarbazepine, pregabalin and topiramate against maximal electroshock-induced seizures in mice

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