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Nonspecific binding of drugs to human liver microsomes

British journal of clinical pharmacology, 2000-05, Vol.49 (5), p.453-461

2000

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The xenobiotic inhibitor profile of cytochrome P4502C8

British journal of clinical pharmacology, 2000-12, Vol.50 (6), p.573-580

2000

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Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

British journal of clinical pharmacology, 1993-12, Vol.36 (6), p.521-530

1993

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Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen

Biochemical pharmacology, 1996-04, Vol.51 (8), p.1003-1008

1996

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Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

Biochemical pharmacology, 1993-12, Vol.46 (11), p.1975-1981

1993

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Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

Biochemical journal, 1993-01, Vol.289 (2), p.533-538

1993

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Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinine

British journal of clinical pharmacology, 1997-03, Vol.43 (3), p.245-252

1997

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Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism

The Journal of pharmacology and experimental therapeutics, 1995-03, Vol.272 (3), p.1076

1995

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Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9

Xenobiotica, 2004, Vol.34 (1), p.49-60

2004

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Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

Biochemical and biophysical research communications, 1991-03, Vol.175 (3), p.1112-1118

1991

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Human cytochrome P450 isoform specificity in the regioselective metabolism of toluene and o-, m- and p-xylene

The Journal of pharmacology and experimental therapeutics, 1996-01, Vol.276 (1), p.101

1996

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Tolbutamide hydroxylation by human liver microsomes: Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

Biochemical pharmacology, 1988-03, Vol.37 (6), p.1137-1144

1988

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Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

British journal of clinical pharmacology, 1991-02, Vol.31 (2), p.125-130

1991

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Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man

British journal of clinical pharmacology, 1986-08, Vol.22 (2), p.177-182

1986

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Quantitative assessment of caffeine partial clearances in man

British journal of clinical pharmacology, 1986-08, Vol.22 (2), p.183-186

1986

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Influence of gender and oral contraceptive steroids on the metabolism of salicylic acid and acetylsalicylic acid

British journal of clinical pharmacology, 1986-08, Vol.22 (2), p.135-142

1986

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[14] Assays of omeprazole metabolism as a substrate probe for human CYP isoforms

Methods in Enzymology, 1996, Vol.272, p.132-139

1996

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Characterisation of theophylline metabolism by human liver microsomes: Inhibition and immunochemical studies

Biochemical pharmacology, 1988-05, Vol.37 (9), p.1651-1659

1988

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Kinetic and inhibitor studies of 4-methylumbelliferone and 1-naphthol glucuronidation in human liver microsomes

Biochemical pharmacology, 1988-02, Vol.37 (4), p.665-671

1988

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Determinants of acetaminophen metabolism: Effect of inducers and inhibitors of drug metabolism on acetaminophen's metabolic pathways

Clinical pharmacology and therapeutics, 1984-04, Vol.35 (4), p.480-486

1984

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Characterization of paracetamol UDP-glucuronosyltransferase activity in human liver microsomes

Biochemical pharmacology, 1990-08, Vol.40 (3), p.595-600

1990

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Differential effects of cimetidine on theophylline metabolic pathways

European journal of clinical pharmacology, 1984-01, Vol.26 (3), p.335-340

1984

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Tolbutamide hydroxylation by human, rabbit and rat liver microsomes and by purified forms of cytochrome P-450

Drug metabolism and disposition, 1990-05, Vol.18 (3), p.356

1990

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Gender and oral contraceptive steroids as determinants of drug glucuronidation: effects on clofibric acid elimination

British journal of clinical pharmacology, 1984-08, Vol.18 (2), p.240-243

1984

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Mechanism of formation of 6-amino-5-(N-methylformylamino)-1-methyluracil and 3,7-dimethyluric acid from theobromine in the rat in vitro: involvement of cytochrome P-450 and a cellular thiol

Xenobiotica, 1990, Vol.20 (8), p.823-833

1990

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Nonspecific binding of drugs to human liver microsomes

The xenobiotic inhibitor profile of cytochrome P4502C8

Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen

Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques

Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinine

Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism

Optimizing bacterial expression of catalytically active human cytochromes P450: comparison of CYP2C8 and CYP2C9

Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

Human cytochrome P450 isoform specificity in the regioselective metabolism of toluene and o-, m- and p-xylene

Tolbutamide hydroxylation by human liver microsomes: Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man

Quantitative assessment of caffeine partial clearances in man

Influence of gender and oral contraceptive steroids on the metabolism of salicylic acid and acetylsalicylic acid

[14] Assays of omeprazole metabolism as a substrate probe for human CYP isoforms

Characterisation of theophylline metabolism by human liver microsomes: Inhibition and immunochemical studies

Kinetic and inhibitor studies of 4-methylumbelliferone and 1-naphthol glucuronidation in human liver microsomes

Determinants of acetaminophen metabolism: Effect of inducers and inhibitors of drug metabolism on acetaminophen's metabolic pathways

Characterization of paracetamol UDP-glucuronosyltransferase activity in human liver microsomes

Differential effects of cimetidine on theophylline metabolic pathways

Tolbutamide hydroxylation by human, rabbit and rat liver microsomes and by purified forms of cytochrome P-450

Gender and oral contraceptive steroids as determinants of drug glucuronidation: effects on clofibric acid elimination

Mechanism of formation of 6-amino-5-(N-methylformylamino)-1-methyluracil and 3,7-dimethyluric acid from theobromine in the rat in vitro: involvement of cytochrome P-450 and a cellular thiol

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