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Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1

The Journal of biological chemistry, 2015-10, Vol.290 (43), p.25795-25804

2015

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Characterization of a Site on PAI-1 That Binds to Vitronectin Outside of the Somatomedin B Domain

The Journal of biological chemistry, 2008-10, Vol.283 (42), p.28487-28496

2008

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Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies

Biochemical journal, 2011-08, Vol.438 (1), p.39-51

2011

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A Urokinase-type Plasminogen Activator-inhibiting Cyclic Peptide with an Unusual P2 Residue and an Extended Protease Binding Surface Demonstrates New Modalities for Enzyme Inhibition

The Journal of biological chemistry, 2005-11, Vol.280 (46), p.38424-38437

2005

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A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior

The Journal of biological chemistry, 2016-07, Vol.291 (29), p.15156-15168

2016

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Design of Specific Serine Protease Inhibitors Based on a Versatile Peptide Scaffold: Conversion of a Urokinase Inhibitor to a Plasma Kallikrein Inhibitor

Journal of medicinal chemistry, 2015-11, Vol.58 (22), p.8868-8876

2015

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A Conjugate of Two tPA-Binding RNA Aptamers Efficiently Inhibits Fibrinolysis

Nucleic acid therapeutics, 2017-04, Vol.27 (2), p.95

2017

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Latency transition of plasminogen activator inhibitor type 1 is evolutionarily conserved

Thrombosis and haemostasis, 2017, Vol.117 (9), p.1688

2017

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Allosteric Inactivation of a Trypsin-Like Serine Protease by An Antibody Binding to the 37- and 70-Loops

Biochemistry (Easton), 2013-10, Vol.52 (40), p.7114-7126

2013

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Antibody-induced Enhancement of Factor VIIa Activity through Distinct Allosteric Pathways

The Journal of biological chemistry, 2012-03, Vol.287 (12), p.8994-9001

2012

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Bicyclic Peptide Inhibitor of Urokinase-Type Plasminogen Activator: Mode of Action

Chembiochem : a European journal of chemical biology, 2013-11, Vol.14 (16), p.2179-2188

2013

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RNA Aptamers as Conformational Probes and Regulatory Agents for Plasminogen Activator Inhibitor-1

Biochemistry (Easton), 2010-05, Vol.49 (19), p.4103-4115

2010

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Three monoclonal antibodies against the serpin protease nexin-1 prevent protease translocation

Thrombosis and haemostasis, 2014-01, Vol.111 (1), p.29

2014

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Novel modes of oestrogen receptor agonism and antagonism by hydroxylated and chlorinated biphenyls, revealed by conformation-specific peptide recognition patterns

Molecular and cellular endocrinology, 2008-06, Vol.287 (1), p.30-39

2008

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Evidence for a Pre-latent Form of the Serpin Plasminogen Activator Inhibitor-1 with a Detached β-Strand 1C

The Journal of biological chemistry, 2006-11, Vol.281 (47), p.36071-36081

2006

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Structural Insight into Inactivation of Plasminogen Activator Inhibitor-1 by a Small-Molecule Antagonist

Chemistry & biology, 2013-02, Vol.20 (2), p.253-261

2013

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Interactions of Plasminogen Activator Inhibitor-1 with Vitronectin Involve an Extensive Binding Surface and Induce Mutual Conformational Rearrangements

Biochemistry (Easton), 2009-03, Vol.48 (8), p.1723-1735

2009

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The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation

Biochemical journal, 2003-04, Vol.371 (Pt 2), p.277-287

2003

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Additivity in Effects of Vitronectin and Monoclonal Antibodies against α-Helix F of Plasminogen Activator Inhibitor-1 on Its Reactions with Target Proteinases

The Journal of biological chemistry, 2005-01, Vol.280 (2), p.1482-1489

2005

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Very Low Density Lipoprotein Receptor Binds and Mediates Endocytosis of Urokinase-type Plasminogen Activator-Type-1 Plasminogen Activator Inhibitor Complex (∗)

The Journal of biological chemistry, 1995-09, Vol.270 (35), p.20855-20861

1995

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Mutational analysis of plasminogen activator inhibitor‐1

European journal of biochemistry, 2003-04, Vol.270 (8), p.1680-1688

2003

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Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor‐1 against inactivating agents

European journal of biochemistry, 2003-04, Vol.270 (8), p.1672-1679

2003

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The role of β-strand 5A of plasminogen activator inhibitor-1 in regulation of its latency transition and inhibitory activity by vitronectin

Biochimica et biophysica acta, 2002-06, Vol.1597 (2), p.301-310

2002

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A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization

The Journal of biological chemistry, 2001-04, Vol.276 (16), p.13077-13086

2001

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Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related protein

Biochemical journal, 2001-07, Vol.357 (Pt 1), p.289-296

2001

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Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1

Characterization of a Site on PAI-1 That Binds to Vitronectin Outside of the Somatomedin B Domain

Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies

A Urokinase-type Plasminogen Activator-inhibiting Cyclic Peptide with an Unusual P2 Residue and an Extended Protease Binding Surface Demonstrates New Modalities for Enzyme Inhibition

A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior

Design of Specific Serine Protease Inhibitors Based on a Versatile Peptide Scaffold: Conversion of a Urokinase Inhibitor to a Plasma Kallikrein Inhibitor

A Conjugate of Two tPA-Binding RNA Aptamers Efficiently Inhibits Fibrinolysis

Latency transition of plasminogen activator inhibitor type 1 is evolutionarily conserved

Allosteric Inactivation of a Trypsin-Like Serine Protease by An Antibody Binding to the 37- and 70-Loops

Antibody-induced Enhancement of Factor VIIa Activity through Distinct Allosteric Pathways

Bicyclic Peptide Inhibitor of Urokinase-Type Plasminogen Activator: Mode of Action

RNA Aptamers as Conformational Probes and Regulatory Agents for Plasminogen Activator Inhibitor-1

Three monoclonal antibodies against the serpin protease nexin-1 prevent protease translocation

Novel modes of oestrogen receptor agonism and antagonism by hydroxylated and chlorinated biphenyls, revealed by conformation-specific peptide recognition patterns

Evidence for a Pre-latent Form of the Serpin Plasminogen Activator Inhibitor-1 with a Detached β-Strand 1C

Structural Insight into Inactivation of Plasminogen Activator Inhibitor-1 by a Small-Molecule Antagonist

Interactions of Plasminogen Activator Inhibitor-1 with Vitronectin Involve an Extensive Binding Surface and Induce Mutual Conformational Rearrangements

The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation

Additivity in Effects of Vitronectin and Monoclonal Antibodies against α-Helix F of Plasminogen Activator Inhibitor-1 on Its Reactions with Target Proteinases

Very Low Density Lipoprotein Receptor Binds and Mediates Endocytosis of Urokinase-type Plasminogen Activator-Type-1 Plasminogen Activator Inhibitor Complex (∗)

Mutational analysis of plasminogen activator inhibitor‐1

Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor‐1 against inactivating agents

The role of β-strand 5A of plasminogen activator inhibitor-1 in regulation of its latency transition and inhibitory activity by vitronectin

A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization

Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related protein

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