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Fifty years of pancreatic islet pathology in human type 1 diabetes: insights gained and progress made

Diabetologia, 2018-12, Vol.61 (12), p.2499-2506

2018

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Differential Insulitic Profiles Determine the Extent of [Beta]-Cell Destruction and the Age at Onset of Type 1 Diabetes

Diabetes (New York, N.Y.), 2016-05, Vol.65 (5), p.1362

2016

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Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes

Diabetologia, 2016-11, Vol.59 (11), p.2448-2458

2016

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Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis

Diabetologia, 2020-06, Vol.63 (6), p.1258-1267

2020

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Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expression and a Lower β-Cell Mass

Nutrients, 2019-03, Vol.11 (3), p.605

2019

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Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells

Diabetologia, 2018-11, Vol.61 (11), p.2344-2355

2018

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Developmentally dynamic changes in DNA methylation in the human pancreas

BMC genomics, 2024-06, Vol.25 (1), p.553-553

2024

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Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes

Diabetologia, 2021-07, Vol.64 (7), p.1626-1641

2021

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HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes

Diabetes (New York, N.Y.), 2019-05, Vol.68 (5), p.988-1001

2019

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Islet inflammation in human type 1 diabetes mellitus

IUBMB life, 2014-11, Vol.66 (11), p.723-734

2014

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Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection

Scientific reports, 2021-08, Vol.11 (1), p.15624-13, Article 15624

2021

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Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage

Diabetologia, 2022-10, Vol.65 (10), p.1701-1709

2022

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Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism

Nature genetics, 2022-11, Vol.54 (11), p.1615-1620

2022

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In Situ Analysis Reveals That CFTR Is Expressed in Only a Small Minority of β-Cells in Normal Adult Human Pancreas

The journal of clinical endocrinology and metabolism, 2020-05, Vol.105 (5), p.1366-1374

2020

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Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes

Diabetes (New York, N.Y.), 2018-04, Vol.67 (4), p.687-696

2018

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Circulating C-Peptide Levels in Living Children and Young People and Pancreatic Beta Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

Diabetes (New York, N.Y.), 2022-07, Vol.71 (7), p.1591-1596

2022

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Immunopathology of the human pancreas in type-I diabetes

Seminars in immunopathology, 2011-01, Vol.33 (1), p.9-21

2011

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The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94 deficient β cells and is overexpressed in type 2 diabetes pancreatic islets

American journal of physiology: endocrinology and metabolism, 2020-06, Vol.318 (6), p.E892-E900

2020

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Reduced Expression of the Co-regulator TLE1 in Type 2 Diabetes Is Associated with Increased Islet α-Cell Number

Endocrinology (Philadelphia), 2020-04, Vol.161 (4)

2020

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The subcellular distribution of cyclin-D1 and cyclin-D3 within human islet cells varies according to the status of the pancreas donor

Diabetologia, 2015-09, Vol.58 (9), p.2056-2063

2015

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Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary?

Diabetologia, 2017-04, Vol.60 (4), p.753-755

2017

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In Situ Analysis Reveals That CFTR Is Expressed in Only a Small Minority of [beta]-Cells in Normal Adult Human Pancreas

The journal of clinical endocrinology and metabolism, 2020-05, Vol.105 (5), p.1366

2020

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Genome-wide interaction of genotype by erythrocyte n-3 fatty acids contributes to phenotypic variance of diabetes-related traits

BMC genomics, 2014-09, Vol.15 (1), p.781-781, Article 781

2014

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Fifty years of pancreatic islet pathology in human type 1 diabetes: insights gained and progress made

Differential Insulitic Profiles Determine the Extent of [Beta]-Cell Destruction and the Age at Onset of Type 1 Diabetes

Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes

Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis

Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expression and a Lower β-Cell Mass

Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells

Developmentally dynamic changes in DNA methylation in the human pancreas

Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes

HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes

Islet inflammation in human type 1 diabetes mellitus

Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection

Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage

Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism

In Situ Analysis Reveals That CFTR Is Expressed in Only a Small Minority of β-Cells in Normal Adult Human Pancreas

Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes

Circulating C-Peptide Levels in Living Children and Young People and Pancreatic Beta Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

Immunopathology of the human pancreas in type-I diabetes

The inducible β5i proteasome subunit contributes to proinsulin degradation in GRP94 deficient β cells and is overexpressed in type 2 diabetes pancreatic islets

Reduced Expression of the Co-regulator TLE1 in Type 2 Diabetes Is Associated with Increased Islet α-Cell Number

The subcellular distribution of cyclin-D1 and cyclin-D3 within human islet cells varies according to the status of the pancreas donor

Re-addressing the 2013 consensus guidelines for the diagnosis of insulitis in human type 1 diabetes: is change necessary?

In Situ Analysis Reveals That CFTR Is Expressed in Only a Small Minority of [beta]-Cells in Normal Adult Human Pancreas

Genome-wide interaction of genotype by erythrocyte n-3 fatty acids contributes to phenotypic variance of diabetes-related traits

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