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Structural identification of a hotspot on CFTR for potentiation

Science (American Association for the Advancement of Science), 2019-06, Vol.364 (6446), p.1184-1188

2019

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Real-Time Tracking and In Vivo Visualization of β‑Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

Journal of the American Chemical Society, 2016-04, Vol.138 (16), p.5334-5340

2016

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Salinomycin kills cancer stem cells by sequestering iron in lysosomes

Nature chemistry, 2017-10, Vol.9 (10), p.1025-1033

2017

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Potential Uses of Olive Oil Secoiridoids for the Prevention and Treatment of Cancer: A Narrative Review of Preclinical Studies

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1234

2021

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Total Syntheses of Thailanstatins A–C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents

Journal of the American Chemical Society, 2018-07, Vol.140 (26), p.8303-8320

2018

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Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13), p.3509-3514

2016

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CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel

Colloids and surfaces, B, Biointerfaces, 2016-07, Vol.143, p.532-546

2016

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Salinomycin: a novel anti-cancer agent with known anti-coccidial activities

Current medicinal chemistry, 2013-11, Vol.20 (33), p.4095-4101

2013

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Genomics-Guided Discovery of Thailanstatins A, B, and C As Pre-mRNA Splicing Inhibitors and Antiproliferative Agents from Burkholderia thailandensis MSMB43

Journal of natural products (Washington, D.C.), 2013-04, Vol.76 (4), p.685-693

2013

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Salinomycin as a drug for targeting human cancer stem cells

BioMed research international, 2012-01, Vol.2012, p.950658-17

2012

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A thiopyran derivative with low murine toxicity with therapeutic potential on lung cancer acting through a NF-κB mediated apoptosis-to-pyroptosis switch

Apoptosis (London), 2019-02, Vol.24 (1-2), p.74-82

2019

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Discovery of Chromane-6-Sulfonamide Derivative as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.16106-16131

2021

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Ecofriendly synthesis of pyrano[2,3‐d]pyrimidine derivatives and related heterocycles with anti‐inflammatory activities

Archiv der Pharmazie (Weinheim), 2020-09, Vol.353 (9), p.e2000084-n/a

2020

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Synthesis, DFT calculation, pharmacological evaluation, and catalytic application in the synthesis of diverse pyrano[2,3-c]pyrazole derivatives

Bioorganic chemistry, 2021-09, Vol.114, p.105136-105136, Article 105136

2021

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De novo strategy with engineering anti-Kasha/Kasha fluorophores enables reliable ratiometric quantification of biomolecules

Nature communications, 2020-02, Vol.11 (1), p.793-793, Article 793

2020

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Enantioselective Synthesis of a Cyclopropane Derivative of Spliceostatin A and Evaluation of Bioactivity

Organic letters, 2018-11, Vol.20 (22), p.7293-7297

2018

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Synthesis and anti-tumor activity evaluation of salinomycin C20- O -alkyl/benzyl oxime derivatives

Organic & biomolecular chemistry, 2022-01, Vol.20 (4), p.870-876

2022

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Synthesis, Antimicrobial Evaluation, DFT, and Molecular Docking Studies of Pyrano [4,3‐b] Pyranone and Pyrano[2,3‐b]Pyridinone Systems

Chemistry & biodiversity, 2024-05, Vol.21 (5), p.e202400243-n/a

2024

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Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.13140-13158

2020

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A peptide-salinomycin conjugate with a bystander effect reduces the stemness characteristics of ovarian cancer cells and enhances drug sensitivity

European journal of medicinal chemistry, 2024-10, Vol.276, p.116701, Article 116701

2024

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Xyloketal B: A marine compound with medicinal potential

Pharmacology & therapeutics (Oxford), 2022-02, Vol.230, p.107963-107963, Article 107963

2022

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Design and Development of Highly Potent HIV‑1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants

Journal of medicinal chemistry, 2017-05, Vol.60 (10), p.4267-4278

2017

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Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues

Journal of natural products (Washington, D.C.), 2014-08, Vol.77 (8), p.1864-1870

2014

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Design, synthesis and biological evaluation of 2-substituted 3-hydroxy-6-methyl-4H-pyran-4-one derivatives as Pseudomonas aeruginosa biofilm inhibitors

European journal of medicinal chemistry, 2018-10, Vol.158, p.753-766

2018

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Nucleolin Is a Functional Binding Protein for Salinomycin in Neuroblastoma Stem Cells

Journal of the American Chemical Society, 2019-02, Vol.141 (8), p.3613-3622

2019

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Structural identification of a hotspot on CFTR for potentiation

Real-Time Tracking and In Vivo Visualization of β‑Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe

Salinomycin kills cancer stem cells by sequestering iron in lysosomes

Potential Uses of Olive Oil Secoiridoids for the Prevention and Treatment of Cancer: A Narrative Review of Preclinical Studies

Total Syntheses of Thailanstatins A–C, Spliceostatin D, and Analogues Thereof. Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological Evaluation, and Discovery of Potent Antitumor Agents

Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel

Salinomycin: a novel anti-cancer agent with known anti-coccidial activities

Genomics-Guided Discovery of Thailanstatins A, B, and C As Pre-mRNA Splicing Inhibitors and Antiproliferative Agents from Burkholderia thailandensis MSMB43

Salinomycin as a drug for targeting human cancer stem cells

A thiopyran derivative with low murine toxicity with therapeutic potential on lung cancer acting through a NF-κB mediated apoptosis-to-pyroptosis switch

Discovery of Chromane-6-Sulfonamide Derivative as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist

Ecofriendly synthesis of pyrano[2,3‐d]pyrimidine derivatives and related heterocycles with anti‐inflammatory activities

Synthesis, DFT calculation, pharmacological evaluation, and catalytic application in the synthesis of diverse pyrano[2,3-c]pyrazole derivatives

De novo strategy with engineering anti-Kasha/Kasha fluorophores enables reliable ratiometric quantification of biomolecules

Enantioselective Synthesis of a Cyclopropane Derivative of Spliceostatin A and Evaluation of Bioactivity

Synthesis and anti-tumor activity evaluation of salinomycin C20- O -alkyl/benzyl oxime derivatives

Synthesis, Antimicrobial Evaluation, DFT, and Molecular Docking Studies of Pyrano [4,3‐b] Pyranone and Pyrano[2,3‐b]Pyridinone Systems

Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans

A peptide-salinomycin conjugate with a bystander effect reduces the stemness characteristics of ovarian cancer cells and enhances drug sensitivity

Xyloketal B: A marine compound with medicinal potential

Design and Development of Highly Potent HIV‑1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants

Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues

Design, synthesis and biological evaluation of 2-substituted 3-hydroxy-6-methyl-4H-pyran-4-one derivatives as Pseudomonas aeruginosa biofilm inhibitors

Nucleolin Is a Functional Binding Protein for Salinomycin in Neuroblastoma Stem Cells

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