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Omega-3 pleiad: The multipoint anti-inflammatory strategy

Critical reviews in food science and nutrition, 2024, Vol.64 (14), p.4817-4832

2024

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Strain-level screening of human gut microbes identifies Blautia producta as a new anti-hyperlipidemic probiotic

Gut microbes, 2023-12, Vol.15 (1), p.2228045-2228045

2023

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Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells

Biochemical pharmacology, 2023-07, Vol.213, p.115590-115590, Article 115590

2023

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Effects of TUG-891, a potent GPR120 agonist, on the physical and oral lipid- coating properties, and secretion of saliva

Physiology & behavior, 2023-06, Vol.265, p.114160-114160, Article 114160

2023

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Lipid-Sensing Receptor FFAR4 Modulates Pulmonary Epithelial Homeostasis following Immunogenic Exposures Independently of the FFAR4 Ligand Docosahexaenoic Acid (DHA)

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7072

2023

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Novel Fat Taste Receptor Agonists Curtail Progressive Weight Gain in Obese Male Mice

Cellular and molecular gastroenterology and hepatology, 2023-01, Vol.15 (3), p.633-663

2023

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Diphenyl Ether Derivatives as Novel GPR120 Agonists for the Treatment of Type 2 Diabetes Mellitus

Chemistry & biodiversity, 2023-01, Vol.20 (1), p.e202200814-n/a

2023

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Discovery of Novel and Selective G-Protein Coupled Receptor 120 (GPR120) Agonists for the Treatment of Type 2 Diabetes Mellitus

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.9018

2022

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Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells

Biochemical pharmacology, 2022-12, Vol.206, p.115328, Article 115328

2022

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GPR120 agonist ameliorated insulin resistance and improved ovarian function

Zygote (Cambridge), 2022-06, Vol.30 (3), p.380-385

2022

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GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome

Journal of neuroinflammation, 2022-05, Vol.19 (1), p.121-121, Article 121

2022

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Free fatty acid receptor 4 responds to endogenous fatty acids to protect the heart from pressure overload

Cardiovascular research, 2022-03, Vol.118 (4), p.1061-1073

2022

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Novel advances in understanding fatty acid–binding G protein–coupled receptors and their roles in controlling energy balance

Nutrition reviews, 2022-01, Vol.80 (2), p.187-199

2022

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The molecular mechanism of phytosphingosine binding to FFAR4/GPR120 differs from that of other fatty acids

FEBS open bio, 2021-11, Vol.11 (11), p.3081-3089

2021

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Does FFAR4 Agonism have Therapeutic Potential in Cardiometabolic Disease?

Endocrinology (Philadelphia), 2021-10, Vol.162 (10), p.1

Lay, Abigail C

2021

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Docosahexaenoic acid ameliorates autoimmune inflammation by activating GPR120 signaling pathway in dendritic cells

International immunopharmacology, 2021-08, Vol.97, p.107698-107698, Article 107698

2021

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FFAR4: A New Player in Cardiometabolic Disease?

Endocrinology (Philadelphia), 2021-08, Vol.162 (8), p.1

2021

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A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice

Biomedicine & pharmacotherapy, 2021-07, Vol.139, p.111613-111613, Article 111613

2021

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Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy

Acta pharmacologica Sinica, 2021-02, Vol.42 (2), p.252-263

2021

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Effect of docosahexaenoic acid, phorbol myristate acetate, and insulin on the interaction of the FFA4 (short isoform) receptor with Rab proteins

European journal of pharmacology, 2020-12, Vol.889, p.173595-173595, Article 173595

2020

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Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

Molecular metabolism (Germany), 2020-12, Vol.42, p.101103-101103, Article 101103

2020

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Effects of Edible Oils with Different n‑6/n‑3 PUFA Ratios on Articular Cartilage Degeneration via Regulating the NF-κB Signaling Pathway

Journal of agricultural and food chemistry, 2020-11, Vol.68 (45), p.12641-12650

2020

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GPR120 agonists for the treatment of diabetes: a patent review (2014 present)

Expert opinion on therapeutic patents, 2020-10, Vol.30 (10), p.729-742

2020

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Fat taste signal transduction and its possible negative modulator components

Progress in lipid research, 2020-07, Vol.79, p.101035-101035, Article 101035

2020

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Omega-3 pleiad: The multipoint anti-inflammatory strategy

Strain-level screening of human gut microbes identifies Blautia producta as a new anti-hyperlipidemic probiotic

Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells

Effects of TUG-891, a potent GPR120 agonist, on the physical and oral lipid- coating properties, and secretion of saliva

Lipid-Sensing Receptor FFAR4 Modulates Pulmonary Epithelial Homeostasis following Immunogenic Exposures Independently of the FFAR4 Ligand Docosahexaenoic Acid (DHA)

Novel Fat Taste Receptor Agonists Curtail Progressive Weight Gain in Obese Male Mice

Diphenyl Ether Derivatives as Novel GPR120 Agonists for the Treatment of Type 2 Diabetes Mellitus

Discovery of Novel and Selective G-Protein Coupled Receptor 120 (GPR120) Agonists for the Treatment of Type 2 Diabetes Mellitus

Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells

GPR120 agonist ameliorated insulin resistance and improved ovarian function

GPR120 modulates epileptic seizure and neuroinflammation mediated by NLRP3 inflammasome

Free fatty acid receptor 4 responds to endogenous fatty acids to protect the heart from pressure overload

Novel advances in understanding fatty acid–binding G protein–coupled receptors and their roles in controlling energy balance

Omega-3 mechanism of action in inflammation and endoplasmic reticulum stress in mononuclear cells from overweight non-alcoholic fatty liver disease participants: study protocol for the "Brazilian Omega Study" (BROS)-a randomized controlled trial

The molecular mechanism of phytosphingosine binding to FFAR4/GPR120 differs from that of other fatty acids

Does FFAR4 Agonism have Therapeutic Potential in Cardiometabolic Disease?

Docosahexaenoic acid ameliorates autoimmune inflammation by activating GPR120 signaling pathway in dendritic cells

FFAR4: A New Player in Cardiometabolic Disease?

A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice

Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy

Effect of docosahexaenoic acid, phorbol myristate acetate, and insulin on the interaction of the FFA4 (short isoform) receptor with Rab proteins

Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

Effects of Edible Oils with Different n‑6/n‑3 PUFA Ratios on Articular Cartilage Degeneration via Regulating the NF-κB Signaling Pathway

GPR120 agonists for the treatment of diabetes: a patent review (2014 present)

Fat taste signal transduction and its possible negative modulator components

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