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Polycomb silencers control cell fate, development and cancer

Nature reviews. Cancer, 2006-11, Vol.6 (11), p.846-856

2006

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Stem cell regulation by polycomb repressors: postponing commitment

Current opinion in cell biology, 2008-04, Vol.20 (2), p.201-207

2008

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Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

Molecular cell, 2010-05, Vol.38 (4), p.603-613

2010

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In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

Cancer cell, 2013-05, Vol.23 (5), p.660-676

2013

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Epigenetics and cancer

Genes & development, 2004-10, Vol.18 (19), p.2315-2335

2004

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BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair

Molecular and Cellular Biology, 2011-05, Vol.31 (10), p.1972-1982

2011

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Structure and E3-ligase activity of the Ring-Ring complex of Polycomb proteins Bmi1 and Ring1b

The EMBO journal, 2006-06, Vol.25 (11), p.2465-2474

2006

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Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice

The Journal of experimental medicine, 2020-06, Vol.217 (6)

2020

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Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer

The Journal of clinical investigation, 2012-05, Vol.122 (5), p.1920-1932

2012

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Association of BMI1 with Polycomb Bodies Is Dynamic and Requires PRC2/EZH2 and the Maintenance DNA Methyltransferase DNMT1

Molecular and Cellular Biology, 2005-12, Vol.25 (24), p.11047-11058

2005

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Stable X Chromosome Inactivation Involves the PRC1 Polycomb Complex and Requires Histone MACROH2A1 and the CULLIN3/SPOP Ubiquitin E3 Ligase

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (21), p.7635-7640

2005

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BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A

Breast cancer research : BCR, 2009-01, Vol.11 (4), p.R63-R63, Article R63

2009

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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Nature (London), 1999-01, Vol.397 (6715), p.164-168

1999

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Control of the Replicative Life Span of Human Fibroblasts by p16 and the Polycomb Protein Bmi-1

Molecular and Cellular Biology, 2003-01, Vol.23 (1), p.389-401

2003

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Rnf2 (Ring1b) Deficiency Causes Gastrulation Arrest and Cell Cycle Inhibition

Proceedings of the National Academy of Sciences - PNAS, 2003-03, Vol.100 (5), p.2468-2473

2003

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Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic

Molecular and Cellular Biology, 1997-04, Vol.17 (4), p.2326-2335

1997

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Polycomb repression: from cellular memory to cellular proliferation and cancer

BBA - Reviews on Cancer, 2002-06, Vol.1602 (2), p.151-161

2002

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Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model

PloS one, 2007-01, Vol.2 (1), p.e156-e156

2007

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EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer

Breast cancer research : BCR, 2008-01, Vol.10 (6), p.R109-R109, Article R109

2008

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Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice

Nature genetics, 2002-09, Vol.32 (1), p.160-165

2002

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Controlling Stem Cell Proliferation: CKIs at Work

Cell cycle (Georgetown, Tex.), 2006-06, Vol.5 (12), p.1281-1285

2006

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Senescence bypass screen identifies TBX2 , which represses Cdkn2a ( p19 ARF ) and is amplified in a subset of human breast cancers

Nature genetics, 2000-11, Vol.26 (3), p.291-299

2000

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Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors

PloS one, 2013-05, Vol.8 (5), p.e62113

2013

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Cancer genes hypermethylated in human embryonic stem cells

PloS one, 2008-09, Vol.3 (9), p.e3294-e3294

2008

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GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors

PloS one, 2012-05, Vol.7 (5), p.e35943-e35943

2012

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Polycomb silencers control cell fate, development and cancer

Stem cell regulation by polycomb repressors: postponing commitment

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

Epigenetics and cancer

BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair

Structure and E3-ligase activity of the Ring-Ring complex of Polycomb proteins Bmi1 and Ring1b

Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer

Association of BMI1 with Polycomb Bodies Is Dynamic and Requires PRC2/EZH2 and the Maintenance DNA Methyltransferase DNMT1

Stable X Chromosome Inactivation Involves the PRC1 Polycomb Complex and Requires Histone MACROH2A1 and the CULLIN3/SPOP Ubiquitin E3 Ligase

BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Control of the Replicative Life Span of Human Fibroblasts by p16 and the Polycomb Protein Bmi-1

Rnf2 (Ring1b) Deficiency Causes Gastrulation Arrest and Cell Cycle Inhibition

Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic

Polycomb repression: from cellular memory to cellular proliferation and cancer

Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice

Controlling Stem Cell Proliferation: CKIs at Work

Senescence bypass screen identifies TBX2 , which represses Cdkn2a ( p19 ARF ) and is amplified in a subset of human breast cancers

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors

Cancer genes hypermethylated in human embryonic stem cells

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors

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