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Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Nature reviews. Molecular cell biology, 2017-03, Vol.18 (3), p.159-174

2017

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Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes

Genome biology, 2014-07, Vol.15 (7), p.418-418, Article 418

2014

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DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

Science (American Association for the Advancement of Science), 2009-04, Vol.324 (5925), p.407-410

2009

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Metabolic gatekeeper function of B-lymphoid transcription factors

Nature (London), 2017-02, Vol.542 (7642), p.479-483

2017

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Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases

Endocrine reviews, 2009-12, Vol.30 (7), p.830-882

2009

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Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C)

The Journal of biological chemistry, 2016-03, Vol.291 (12), p.6060-6070

2016

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Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (40), p.15858-15863

2007

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Cell- and gene-specific regulation of primary target genes by the androgen receptor

Genes & development, 2007-08, Vol.21 (16), p.2005-2017

2007

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Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor

PLoS genetics, 2007-06, Vol.3 (6), p.e94-e94

2007

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Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones

Science (American Association for the Advancement of Science), 2002-06, Vol.296 (5576), p.2232-2235

2002

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The Glucocorticoid Receptor and the Coregulator Brm Selectively Modulate Each Other's Occupancy and Activity in a Gene-Specific Manner

Molecular and Cellular Biology, 2011-08, Vol.31 (16), p.3267-3276

2011

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Chromatin Immunoprecipitation (ChIP) Scanning Identifies Primary Glucocorticoid Receptor Target Genes

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (44), p.15603-15608

2004

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Non-competitive androgen receptor inhibition in vitro and in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7233-7238

2009

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Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (5), p.1964-1969

2013

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Leveraging crowdsourcing to facilitate the discovery of new medicines

Science translational medicine, 2011-06, Vol.3 (88), p.88mr1

2011

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Regulatory Actions of Glucocorticoid Hormones: From Organisms to Mechanisms

Advances in experimental medicine and biology, 2015, Vol.872, p.3

2015

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Alternate Surfaces of Transcriptional Coregulator GRIP1 Function in Different Glucocorticoid Receptor Activation and Repression Contexts

Proceedings of the National Academy of Sciences - PNAS, 2002-12, Vol.99 (26), p.16701-16706

2002

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Conservation analysis predicts in vivo occupancy of glucocorticoid receptor-binding sequences at glucocorticoid-induced genes

Proceedings of the National Academy of Sciences - PNAS, 2008-04, Vol.105 (15), p.5745-5749

2008

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Target-Specific Utilization of Transcriptional Regulatory Surfaces by the Glucocorticoid Receptor

Proceedings of the National Academy of Sciences - PNAS, 2003-11, Vol.100 (24), p.13845-13850

2003

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Occupancy of chromatin organizers in the Epstein–Barr virus genome

Virology (New York, N.Y.), 2011-06, Vol.415 (1), p.1-5

2011

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Precision medicine: Beyond the inflection point

Science translational medicine, 2015-08, Vol.7 (300), p.300ps17

2015

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Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity

Genes & development, 2006-03, Vol.20 (6), p.689-699

2006

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A New Tool for Inducible Gene Expression in Caenorhabditis elegans

Genetics (Austin), 2019-02, Vol.211 (2), p.419-430

2019

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Reciprocal intronic and exonic histone modification regions in humans

Nature structural & molecular biology, 2010-12, Vol.17 (12), p.1495-1499

2010

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Science as a Way of Knowing: From Protein Machines to Evidence-Based Decisions

Cell, 2016-09, Vol.167 (1), p.16-19

2016

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Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

Metabolic gatekeeper function of B-lymphoid transcription factors

Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases

Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C)

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Cell- and gene-specific regulation of primary target genes by the androgen receptor

Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor

Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones

The Glucocorticoid Receptor and the Coregulator Brm Selectively Modulate Each Other's Occupancy and Activity in a Gene-Specific Manner

Chromatin Immunoprecipitation (ChIP) Scanning Identifies Primary Glucocorticoid Receptor Target Genes

Non-competitive androgen receptor inhibition in vitro and in vivo

Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action

Leveraging crowdsourcing to facilitate the discovery of new medicines

Regulatory Actions of Glucocorticoid Hormones: From Organisms to Mechanisms

Alternate Surfaces of Transcriptional Coregulator GRIP1 Function in Different Glucocorticoid Receptor Activation and Repression Contexts

Conservation analysis predicts in vivo occupancy of glucocorticoid receptor-binding sequences at glucocorticoid-induced genes

Target-Specific Utilization of Transcriptional Regulatory Surfaces by the Glucocorticoid Receptor

Occupancy of chromatin organizers in the Epstein–Barr virus genome

Precision medicine: Beyond the inflection point

Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity

A New Tool for Inducible Gene Expression in Caenorhabditis elegans

Reciprocal intronic and exonic histone modification regions in humans

Science as a Way of Knowing: From Protein Machines to Evidence-Based Decisions

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