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Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies

Annual review of medicine, 2015-01, Vol.66 (1), p.145-159

2015

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On the Alert for Cytokine Storm: Immunopathology in COVID‐19

Arthritis & rheumatology (Hoboken, N.J.), 2020-07, Vol.72 (7), p.1059-1063

2020

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Systemic juvenile idiopathic arthritis and macrophage activation syndrome: update on pathogenesis and treatment

Current opinion in rheumatology, 2018-09, Vol.30 (5), p.514-520

2018

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Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease: Characterization and Risk Factors

Arthritis & rheumatology (Hoboken, N.J.), 2019-11, Vol.71 (11), p.1943-1954

2019

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Macrophage activation syndrome and cytokine-directed therapies

Best practice & research. Clinical rheumatology, 2014-04, Vol.28 (2), p.277-292

2014

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IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Rheumatology (Oxford, England), 2020-02, Vol.59 (2), p.361-366

2020

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Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

The Journal of infectious diseases, 2016-04, Vol.213 (7), p.1180-1188

2016

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Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation

Nature immunology, 2021-06, Vol.22 (6), p.711-722

2021

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Identification of Distinct Inflammatory Programs and Biomarkers in Systemic Juvenile Idiopathic Arthritis and Related Lung Disease by Serum Proteome Analysis

Arthritis & rheumatology (Hoboken, N.J.), 2022-07, Vol.74 (7), p.1271-1283

2022

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Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis

Annals of the rheumatic diseases, 2020-02, Vol.79 (2), p.225-231

2020

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Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis

The Journal of clinical investigation, 2023-11, Vol.133 (22), p.1-18

2023

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Complications of complications: diagnosis and treatment of recurrent macrophage activation syndrome in a patient with well-controlled systemic juvenile idiopathic arthritis

Rheumatic & musculoskeletal diseases open, 2023-01, Vol.9 (1), p.e002611

2023

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Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease

Frontiers in immunology, 2018-12, Vol.9, p.2995-2995

2018

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S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis

Arthritis research & therapy, 2024-06, Vol.26 (1), p.125-12, Article 125

2024

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Spectrum of severity of multisystem inflammatory syndrome in children: an EHR-based cohort study from the RECOVER program

Scientific reports, 2023-11, Vol.13 (1), p.21005-21005, Article 21005

2023

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Differential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor

Journal of leukocyte biology, 2006-09, Vol.80 (3), p.563-571

2006

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COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

Translational research : the journal of laboratory and clinical medicine, 2021-06, Vol.232, p.1-12

2021

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Molecular Pathways in the Pathogenesis of Systemic Juvenile Idiopathic Arthritis

Rheumatic diseases clinics of North America, 2023-11, Vol.49 (4), p.895-911

2023

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Genetics of Acquired Cytokine Storm Syndromes : Secondary HLH Genetics

Advances in experimental medicine and biology, 2024, Vol.1448, p.103

2024

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Interfering with interferons: targeting the JAK-STAT pathway in complications of systemic juvenile idiopathic arthritis (SJIA)

Rheumatology (Oxford, England), 2022-03, Vol.61 (3), p.926-935

2022

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New developments related to lung complications in pediatric rheumatic disease

Current opinion in rheumatology, 2023-09, Vol.35 (5), p.273-277

2023

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American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV‐2 and Hyperinflammation in Pediatric COVID‐19: Version 2

Arthritis & rheumatology (Hoboken, N.J.), 2021-04, Vol.73 (4), p.e13-e29

2021

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American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV‐2 and Hyperinflammation in Pediatric COVID‐19: Version 1

Arthritis & rheumatology (Hoboken, N.J.), 2020-11, Vol.72 (11), p.1791-1805

2020

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American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV‐2 and Hyperinflammation in Pediatric COVID‐19: Version 3

Arthritis & rheumatology (Hoboken, N.J.), 2022-04, Vol.74 (4), p.e1-e20

2022

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Francisella tularensis Genes Required for Inhibition of the Neutrophil Respiratory Burst and Intramacrophage Growth Identified by Random Transposon Mutagenesis of Strain LVS

Infection and Immunity, 2009-04, Vol.77 (4), p.1324-1336

2009

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Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies

On the Alert for Cytokine Storm: Immunopathology in COVID‐19

Systemic juvenile idiopathic arthritis and macrophage activation syndrome: update on pathogenesis and treatment

Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease: Characterization and Risk Factors

Macrophage activation syndrome and cytokine-directed therapies

IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation

Identification of Distinct Inflammatory Programs and Biomarkers in Systemic Juvenile Idiopathic Arthritis and Related Lung Disease by Serum Proteome Analysis

Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis

Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis

Complications of complications: diagnosis and treatment of recurrent macrophage activation syndrome in a patient with well-controlled systemic juvenile idiopathic arthritis

Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease

S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis

Spectrum of severity of multisystem inflammatory syndrome in children: an EHR-based cohort study from the RECOVER program

Differential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor

COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

Molecular Pathways in the Pathogenesis of Systemic Juvenile Idiopathic Arthritis

Genetics of Acquired Cytokine Storm Syndromes : Secondary HLH Genetics

Interfering with interferons: targeting the JAK-STAT pathway in complications of systemic juvenile idiopathic arthritis (SJIA)

New developments related to lung complications in pediatric rheumatic disease

American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV‐2 and Hyperinflammation in Pediatric COVID‐19: Version 2

American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV‐2 and Hyperinflammation in Pediatric COVID‐19: Version 1

American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV‐2 and Hyperinflammation in Pediatric COVID‐19: Version 3

Francisella tularensis Genes Required for Inhibition of the Neutrophil Respiratory Burst and Intramacrophage Growth Identified by Random Transposon Mutagenesis of Strain LVS

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