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The SREBP pathway - insights from insigs and insects

Nature reviews. Molecular cell biology, 2003-08, Vol.4 (8), p.631-640

Rawson, Robert B

2003

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Health technology assessment and price negotiation alignment for rare disorder drugs in Canada: Who benefits?

Orphanet journal of rare diseases, 2022-06, Vol.17 (1), p.218-218, Article 218

Rawson, Nigel S B

2022

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National Pharmacare in Canada: Equality or Equity, Accessibility or Affordability Comment on "Universal Pharmacare in Canada: A Prescription for Equity in Healthcare"

International journal of health policy and management, 2020-12, Vol.9 (12), p.524-527

Rawson, Nigel S B

2020

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New Anticancer Drugs: Reliably Assessing "Value" While Addressing High Prices

Current oncology (Toronto), 2024-04, Vol.31 (5), p.2453-2480

2024

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ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs

Molecular cell, 2000-12, Vol.6 (6), p.1355-1364

2000

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Access to Oncology Medicines in Canada: Consensus Forum for Recommendations for Improvement

Current oncology (Toronto), 2024-04, Vol.31 (4), p.1803-1816

2024

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Leading Causes of Mortality and Prescription Drug Coverage in Canada and New Zealand

Frontiers in public health, 2020-10, Vol.8, p.544835-544835

Rawson, Nigel S B

2020

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The site-2 protease

Biochimica et biophysica acta, 2013-12, Vol.1828 (12), p.2801-2807

Rawson, Robert B.

2013

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

Cell, 2000-02, Vol.100 (4), p.391-398

2000

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Drug safety: withdrawn medications are only part of the picture

BMC medicine, 2016-02, Vol.14 (28), p.28-28, Article 28

Rawson, Nigel S B

2016

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The impact of willingness-to-pay threshold on price reduction recommendations for oncology drugs: a review of assessments conducted by the Canadian Agency for Drugs and Technologies in Health

Journal of comparative effectiveness research, 2024-05, Vol.13 (5), p.e230178-e230178

2024

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The SREBP Pathway in Drosophila: Regulation by Palmitate, Not Sterols

Developmental cell, 2002-02, Vol.2 (2), p.229-238

2002

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Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients

British journal of cancer, 2011-06, Vol.104 (12), p.1906-1912

2011

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Molecular Identification of the Sterol-Regulated Luminal Protease that Cleaves SREBPs and Controls Lipid Composition of Animal Cells

Molecular cell, 1998-10, Vol.2 (4), p.505-514

1998

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Sterol-Regulated Release of SREBP-2 from Cell Membranes Requires Two Sequential Cleavages, One Within a Transmembrane Segment

Cell, 1996-06, Vol.85 (7), p.1037-1046

1996

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Complementation Cloning of S2P, a Gene Encoding a Putative Metalloprotease Required for Intramembrane Cleavage of SREBPs

Molecular cell, 1997-12, Vol.1 (1), p.47-57

1997

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Epigenetic biomarkers in colorectal cancer diagnostics

Expert review of molecular diagnostics, 2012-06, Vol.12 (5), p.499-509

2012

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Isolation of Mutant Cells Lacking Insig-1 through Selection with SR-12813, an Agent That Stimulates Degradation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.43136-43147

2004

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Health Canada's use of priority review status for drugs for unmet needs

Regulatory toxicology and pharmacology, 2015-10, Vol.73 (1), p.391-395

Rawson, Nigel S.B.

2015

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Manitoba and Saskatchewan administrative health care utilization databases are used differently to answer epidemiologic research questions

Journal of clinical epidemiology, 2008-02, Vol.61 (2), p.192-197.e12

2008

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Membrane Topology of S2P, a Protein Required for Intramembranous Cleavage of Sterol Regulatory Element-binding Proteins

The Journal of biological chemistry, 1999-07, Vol.274 (31), p.21973-21980

1999

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Importation of drugs into the United States from Canada

Canadian Medical Association journal (CMAJ), 2017-06, Vol.189 (24), p.E817-E818

2017

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Healthcare Databases for Drug Safety Research: Data Validity Assessment Remains Crucial

Drug safety, 2018-09, Vol.41 (9), p.829-833

2018

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Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study

Clinical cancer research, 2014-09, Vol.20 (18), p.4962-4970

2014

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Health technology assessment of new drugs for rare disorders in Canada: impact of disease prevalence and cost

Orphanet journal of rare diseases, 2017-03, Vol.12 (1), p.59-59, Article 59

Rawson, Nigel S B

2017

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The SREBP pathway - insights from insigs and insects

Health technology assessment and price negotiation alignment for rare disorder drugs in Canada: Who benefits?

National Pharmacare in Canada: Equality or Equity, Accessibility or Affordability Comment on "Universal Pharmacare in Canada: A Prescription for Equity in Healthcare"

New Anticancer Drugs: Reliably Assessing "Value" While Addressing High Prices

ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs

Access to Oncology Medicines in Canada: Consensus Forum for Recommendations for Improvement

Leading Causes of Mortality and Prescription Drug Coverage in Canada and New Zealand

The site-2 protease

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

Drug safety: withdrawn medications are only part of the picture

The impact of willingness-to-pay threshold on price reduction recommendations for oncology drugs: a review of assessments conducted by the Canadian Agency for Drugs and Technologies in Health

The SREBP Pathway in Drosophila: Regulation by Palmitate, Not Sterols

Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients

Molecular Identification of the Sterol-Regulated Luminal Protease that Cleaves SREBPs and Controls Lipid Composition of Animal Cells

Sterol-Regulated Release of SREBP-2 from Cell Membranes Requires Two Sequential Cleavages, One Within a Transmembrane Segment

Complementation Cloning of S2P, a Gene Encoding a Putative Metalloprotease Required for Intramembrane Cleavage of SREBPs

Epigenetic biomarkers in colorectal cancer diagnostics

Isolation of Mutant Cells Lacking Insig-1 through Selection with SR-12813, an Agent That Stimulates Degradation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase

Health Canada's use of priority review status for drugs for unmet needs

Manitoba and Saskatchewan administrative health care utilization databases are used differently to answer epidemiologic research questions

Membrane Topology of S2P, a Protein Required for Intramembranous Cleavage of Sterol Regulatory Element-binding Proteins

Importation of drugs into the United States from Canada

Healthcare Databases for Drug Safety Research: Data Validity Assessment Remains Crucial

Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study

Health technology assessment of new drugs for rare disorders in Canada: impact of disease prevalence and cost

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