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Discovery and development of VX-950, a novel, covalent, and reversible inhibitor of hepatitis C virus NS3.4A serine protease

Infectious disorders drug targets, 2006-03, Vol.6 (1), p.3-16

2006

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Inhibition of Human Hepatitis B Virus Replication by AT-61, a Phenylpropenamide Derivative, Alone and in Combination with (−)β-l-2′,3′-Dideoxy-3′-Thiacytidine

Antimicrobial Agents and Chemotherapy, 1998-12, Vol.42 (12), p.3179-3186

1998

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Synthesis and Antitumor Activity of 4-Aminomethylthioxanthenone and 5-Aminomethylbenzothiopyranoindazole Derivatives

Journal of medicinal chemistry, 1998-09, Vol.41 (19), p.3645-3654

1998

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Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease

Antimicrobial Agents and Chemotherapy, 2006-03, Vol.50 (3), p.899-909

2006

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In Vitro Studies of Cross-resistance Mutations against Two Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

The Journal of biological chemistry, 2005-11, Vol.280 (44), p.36784-36791

2005

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Antiviral properties of 3-quinolinecarboxamides: a series of novel non-nucleoside antiherpetic agents

Drug design and discovery, 1997-05, Vol.15 (1), p.25

1997

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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Nature, 2007-11, Vol.450 (7170), p.712-716

2007

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Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes

The Journal of biological chemistry, 2009-09, Vol.284 (36), p.24394-24405

2009

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Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6124), p.1216-1219

2013

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Discovery of oxazolo[4,5- b]pyridines and related heterocyclic analogs as novel SIRT1 activators

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (8), p.2350-2353

2009

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Mycoplasma hominis and Ureaplasma urealyticum in midtrimester amniotic fluid: Association with amniotic fluid cytokine levels and pregnancy outcome

American journal of obstetrics and gynecology, 2004-10, Vol.191 (4), p.1382-1386

2004

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Intraobserver and interobserver reproducibility of fetal biometry

Ultrasound in obstetrics & gynecology, 2004-11, Vol.24 (6), p.654-658

2004

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Response of treatment-naive brain metastases to stereotactic radiosurgery

Nature communications, 2024-05, Vol.15 (1), p.3728-3728, Article 3728

2024

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Interleukin-4 and -10 gene polymorphisms and spontaneous preterm birth in multifetal gestations

American journal of obstetrics and gynecology, 2004-03, Vol.190 (3), p.702-706

2004

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First trimester prediction of growth discordance in twin gestations

American journal of obstetrics and gynecology, 2003-09, Vol.189 (3), p.706-709

2003

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Clinical significance of first trimester crown-rump length disparity in dichorionic twin gestations

American journal of obstetrics and gynecology, 2004-10, Vol.191 (4), p.1437-1440

2004

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Discovery of benzothiazole derivatives as efficacious and enterocyte-specific MTP inhibitors

Bioorganic & medicinal chemistry letters, 2009-03, Vol.19 (5), p.1416-1420

2009

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Clinical use of first-trimester aneuploidy screening in a United States population can replicate data from clinical trials

American journal of obstetrics and gynecology, 2006, Vol.194 (1), p.127-130

2006

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A single nucleotide A>G polymorphism at position −670 in the Fas gene promoter: Relationship to preterm premature rupture of fetal membranes in multifetal pregnancies

American journal of obstetrics and gynecology, 2005, Vol.192 (1), p.208-212

2005

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Interleukin-1 receptor antagonist gene polymorphism and multifetal pregnancy outcome

American journal of obstetrics and gynecology, 2003-10, Vol.189 (4), p.911-914

2003

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Polymorphisms in the tumor necrosis factor-α gene at position −308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes

American journal of obstetrics and gynecology, 2004-10, Vol.191 (4), p.1368-1374

2004

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Differential expression of immune system–related components in midtrimester amniotic fluid from singleton and twin pregnancies

American journal of obstetrics and gynecology, 2005-09, Vol.193 (3), p.942-946

2005

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Association of Amniotic Fluid Index With Estimated Fetal Weight

Journal of ultrasound in medicine, 2004-11, Vol.23 (11), p.1449-1452

2004

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Atypical sonographic presentation of fetal unilateral inguinoscrotal hernia in a multiple gestation

Journal of perinatal medicine, 2004-01, Vol.32 (4), p.378-380

2004

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Discovery and development of VX-950, a novel, covalent, and reversible inhibitor of hepatitis C virus NS3.4A serine protease

Inhibition of Human Hepatitis B Virus Replication by AT-61, a Phenylpropenamide Derivative, Alone and in Combination with (−)β-l-2′,3′-Dideoxy-3′-Thiacytidine

Synthesis and Antitumor Activity of 4-Aminomethylthioxanthenone and 5-Aminomethylbenzothiopyranoindazole Derivatives

Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease

In Vitro Studies of Cross-resistance Mutations against Two Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

Antiviral properties of 3-quinolinecarboxamides: a series of novel non-nucleoside antiherpetic agents

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes

Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

Investigation of radiomic signatures for local recurrence using primary tumor texture analysis in oropharyngeal head and neck cancer patients

Discovery of oxazolo[4,5- b]pyridines and related heterocyclic analogs as novel SIRT1 activators

Mycoplasma hominis and Ureaplasma urealyticum in midtrimester amniotic fluid: Association with amniotic fluid cytokine levels and pregnancy outcome

Intraobserver and interobserver reproducibility of fetal biometry

Response of treatment-naive brain metastases to stereotactic radiosurgery

Interleukin-4 and -10 gene polymorphisms and spontaneous preterm birth in multifetal gestations

First trimester prediction of growth discordance in twin gestations

Clinical significance of first trimester crown-rump length disparity in dichorionic twin gestations

Discovery of benzothiazole derivatives as efficacious and enterocyte-specific MTP inhibitors

Clinical use of first-trimester aneuploidy screening in a United States population can replicate data from clinical trials

A single nucleotide A>G polymorphism at position −670 in the Fas gene promoter: Relationship to preterm premature rupture of fetal membranes in multifetal pregnancies

Interleukin-1 receptor antagonist gene polymorphism and multifetal pregnancy outcome

Polymorphisms in the tumor necrosis factor-α gene at position −308 and the inducible 70 kd heat shock protein gene at position +1267 in multifetal pregnancies and preterm premature rupture of fetal membranes

Differential expression of immune system–related components in midtrimester amniotic fluid from singleton and twin pregnancies

Association of Amniotic Fluid Index With Estimated Fetal Weight

Atypical sonographic presentation of fetal unilateral inguinoscrotal hernia in a multiple gestation

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