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Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence

Journal of applied toxicology, 2014-06, Vol.34 (6), p.595-606

2014

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New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis

Journal of applied toxicology, 2014-01, Vol.34 (1), p.1-18

2014

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How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology

Toxicological sciences, 2017-02, Vol.155 (2), p.326-336

2017

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IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans

Critical reviews in toxicology, 2006-11, Vol.36 (10), p.781-792

2006

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Procedural application of mode-of-action and human relevance analysis: styrene-induced lung tumors in mice

Critical reviews in toxicology, 2024-02, Vol.54 (2), p.134-151

2024

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Adverse Outcome Pathways-Organizing Toxicological Information to Improve Decision Making

The Journal of pharmacology and experimental therapeutics, 2016-01, Vol.356 (1), p.170

2016

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Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

Neurotoxicology (Park Forest South), 2017-03, Vol.59, p.240-255

2017

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A user-friendly tool to assess combined exposures to indoor air pollutants in public spaces of children

Food and chemical toxicology, 2022-07, Vol.165, p.113141, Article 113141

2022

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An international, multicenter study of intravenous bevacizumab for bleeding in hereditary hemorrhagic telangiectasia: the InHIBIT-Bleed study

Haematologica (Roma), 2021-08, Vol.106 (8), p.2161

2021

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Evolution of chemical-specific adjustment factors (CSAF) based on recent international experience; increasing utility and facilitating regulatory acceptance

Critical reviews in toxicology, 2017-10, Vol.47 (9), p.733-753

2017

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A Framework for Human Relevance Analysis of Information on Carcinogenic Modes of Action

Critical reviews in toxicology, 2003-01, Vol.33 (6), p.591-653

2003

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Development of the adverse outcome pathway "alkylation of DNA in male premeiotic germ cells leading to heritable mutations" using the OECD's users' handbook supplement

Environmental and molecular mutagenesis, 2015-12, Vol.56 (9), p.724-750

2015

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Lightly Embalmed Cadavers as a Training Tool for Ultrasound-Guided Procedures Commonly Used in Interventional Radiology

Academic radiology, 2018-11, Vol.25 (11), p.1503-1509

2018

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4-Aminobiphenyl and DNA Reactivity: Case Study Within the Context of the 2006 IPCS Human Relevance Framework for Analysis of a Cancer Mode of Action for Humans

Critical reviews in toxicology, 2006-11, Vol.36 (10), p.803-819

2006

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Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity

Pharmacology & therapeutics (Oxford), 2017-11, Vol.179, p.84-95

2017

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Gaining acceptance for the use of in vitro toxicity assays and QIVIVE in regulatory risk assessment

Toxicology (Amsterdam), 2015-06, Vol.332, p.112-123

2015

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Using mode of action information to improve regulatory decision-making: An ECETOC/ILSI RF/HESI workshop overview

Critical reviews in toxicology, 2011-03, Vol.41 (3), p.175-186

2011

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Framework for human health risk assessment of non-cancer effects resulting from short-duration and intermittent exposures to chemicals

Journal of applied toxicology, 2016-09, Vol.36 (9), p.1077-1089

2016

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Phosphorylation and 14‐3‐3 binding of Arabidopsis trehalose‐phosphate synthase 5 in response to 2‐deoxyglucose

The Plant journal : for cell and molecular biology, 2006-07, Vol.47 (2), p.211-223

2006

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Application of benchmark dose modeling to protein expression data in the development and analysis of mode of action/adverse outcome pathways for testicular toxicity

Journal of applied toxicology, 2014-11, Vol.34 (11), p.1115-1121

2014

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Overview: Using Mode of Action and Life Stage Information to Evaluate the Human Relevance of Animal Toxicity Data

Critical reviews in toxicology, 2005-10, Vol.35 (8-9), p.663-672

2005

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Comprehensive Proteomic Analysis of Interphase and Mitotic 14-3-3-binding Proteins

The Journal of biological chemistry, 2004-07, Vol.279 (31), p.32046-32054

2004

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Case study illustrating the WHO IPCS guidance on characterization and application of physiologically based pharmacokinetic models in risk assessment

Regulatory toxicology and pharmacology, 2013-06, Vol.66 (1), p.116-129

2013

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Emotion regulation in the context of frustration in children with high functioning autism and their typical peers

Journal of child psychology and psychiatry, 2012-12, Vol.53 (12), p.1250-1258

2012

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The Human Relevance of Information on Carcinogenic Modes of Action: Overview

Critical reviews in toxicology, 2003-01, Vol.33 (6), p.581-589

2003

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Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence

New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis

How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology

IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans

Procedural application of mode-of-action and human relevance analysis: styrene-induced lung tumors in mice

Adverse Outcome Pathways-Organizing Toxicological Information to Improve Decision Making

Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

A user-friendly tool to assess combined exposures to indoor air pollutants in public spaces of children

An international, multicenter study of intravenous bevacizumab for bleeding in hereditary hemorrhagic telangiectasia: the InHIBIT-Bleed study

Evolution of chemical-specific adjustment factors (CSAF) based on recent international experience; increasing utility and facilitating regulatory acceptance

A Framework for Human Relevance Analysis of Information on Carcinogenic Modes of Action

Development of the adverse outcome pathway "alkylation of DNA in male premeiotic germ cells leading to heritable mutations" using the OECD's users' handbook supplement

Lightly Embalmed Cadavers as a Training Tool for Ultrasound-Guided Procedures Commonly Used in Interventional Radiology

4-Aminobiphenyl and DNA Reactivity: Case Study Within the Context of the 2006 IPCS Human Relevance Framework for Analysis of a Cancer Mode of Action for Humans

Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity

Gaining acceptance for the use of in vitro toxicity assays and QIVIVE in regulatory risk assessment

Using mode of action information to improve regulatory decision-making: An ECETOC/ILSI RF/HESI workshop overview

Framework for human health risk assessment of non-cancer effects resulting from short-duration and intermittent exposures to chemicals

Phosphorylation and 14‐3‐3 binding of Arabidopsis trehalose‐phosphate synthase 5 in response to 2‐deoxyglucose

Application of benchmark dose modeling to protein expression data in the development and analysis of mode of action/adverse outcome pathways for testicular toxicity

Overview: Using Mode of Action and Life Stage Information to Evaluate the Human Relevance of Animal Toxicity Data

Comprehensive Proteomic Analysis of Interphase and Mitotic 14-3-3-binding Proteins

Case study illustrating the WHO IPCS guidance on characterization and application of physiologically based pharmacokinetic models in risk assessment

Emotion regulation in the context of frustration in children with high functioning autism and their typical peers

The Human Relevance of Information on Carcinogenic Modes of Action: Overview

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