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Familial dysbetalipoproteinemia: an underdiagnosed lipid disorder

Current opinion in endocrinology, diabetes, and obesity, 2017-04, Vol.24 (2), p.133-139

2017

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Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

The Lancet (British edition), 2010-03, Vol.375 (9719), p.998-1006

2010

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Lomitapide and Mipomersen—Inhibiting Microsomal Triglyceride Transfer Protein (MTP) and apoB100 Synthesis

Current atherosclerosis reports, 2019-11, Vol.21 (12), p.48-48, Article 48

2019

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The C679X mutation in PCSK9 is present and lowers blood cholesterol in a Southern African population

Atherosclerosis, 2007-08, Vol.193 (2), p.445-448

2007

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Effect of adding bezafibrate to standard lipid-lowering therapy on post-fat load lipid levels in patients with familial dysbetalipoproteinemia. A randomized placebo-controlled crossover trial

Journal of lipid research, 2017-11, Vol.58 (11), p.2180-2187

2017

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Dietary lipid modification for mild and severe dyslipidaemias

Proceedings of the Nutrition Society, 2013-08, Vol.72 (3), p.337-341

Marais, A. David

2013

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Tracking the ancestry of known and ‘ghost’ homeologous subgenomes in model grass Brachypodium polyploids

The Plant journal : for cell and molecular biology, 2022-03, Vol.109 (6), p.1535-1558

2022

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Dysbetalipoproteinemia: an extreme disorder of remnant metabolism

Current opinion in lipidology, 2015-08, Vol.26 (4), p.292-297

Marais, David

2015

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Elevated Plasma PCSK9 Level Is Equally Detrimental for Patients With Nonfamilial Hypercholesterolemia and Heterozygous Familial Hypercholesterolemia, Irrespective of Low-Density Lipoprotein Receptor Defects

Journal of the American College of Cardiology, 2014-06, Vol.63 (22), p.2365-2373

2014

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Colesevelam Hydrochloride: Efficacy and Safety in Pediatric Subjects with Heterozygous Familial Hypercholesterolemia

The Journal of pediatrics, 2010-02, Vol.156 (2), p.231-236.e3

2010

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Proprotein convertase subtilisin/kexin type 9 inhibition

Current opinion in lipidology, 2012-12, Vol.23 (6), p.511-517

2012

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Comparative aspects of the care of familial hypercholesterolemia in the “Ten Countries Study”

Journal of clinical lipidology, 2019-03, Vol.13 (2), p.287-300

2019

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Normalization of Low-Density Lipoprotein Receptor Expression in Receptor Defective Homozygous Familial Hypercholesterolemia by Inhibition of PCSK9 With Alirocumab

Journal of the American College of Cardiology, 2014-12, Vol.64 (21), p.2299-2300

2014

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Translational Research for Improving the Care of Familial Hypercholesterolemia: The “Ten Countries Study” and Beyond

Journal of Atherosclerosis and Thrombosis, 2016/08/01, Vol.23(8), pp.891-900

2016

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Autosomal dominant familial dysbetalipoproteinemia: A pathophysiological framework and practical approach to diagnosis and therapy

Journal of clinical lipidology, 2017-01, Vol.11 (1), p.12-23.e1

2017

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Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation

The Journal of infectious diseases, 2014-03, Vol.209 (5), p.754-763

2014

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Cardiovascular risk factors in patients with Addison's disease: a comparative study of South African and Swedish patients

PloS one, 2014-03, Vol.9 (6), p.e90768

2014

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RNA-based therapy in the management of lipid disorders: a review

Lipids in health and disease, 2022-04, Vol.21 (1), p.41-41, Article 41

2022

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Tendon xanthomas: Not always familial hypercholesterolemia

Journal of clinical lipidology, 2016-09, Vol.10 (5), p.1262-1265

2016

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PCSK9 inhibition in LDL cholesterol reduction: genetics and therapeutic implications of very low plasma lipoprotein levels

Pharmacology & therapeutics (Oxford), 2015-01, Vol.145, p.58-66

2015

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Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia

The New England journal of medicine, 2008-04, Vol.358 (14), p.1431-1443

2008

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A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations

Diabetes (New York, N.Y.), 2018-06, Vol.67 (6), p.1086-1092

2018

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Genetic and Mechanistic Insights into the Modulation of Circulating Lipoprotein (a) Concentration by Apolipoprotein E Isoforms

Current atherosclerosis reports, 2022-06, Vol.24 (6), p.399-405

2022

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Adiposity and the development of dyslipidemia in APOE ε2 homozygous subjects: A longitudinal analysis in two population-based cohorts

Atherosclerosis, 2021-05, Vol.325, p.57-62

2021

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Familial dysbetalipoproteinemia: an underdiagnosed lipid disorder

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial

Lomitapide and Mipomersen—Inhibiting Microsomal Triglyceride Transfer Protein (MTP) and apoB100 Synthesis

The C679X mutation in PCSK9 is present and lowers blood cholesterol in a Southern African population

Effect of adding bezafibrate to standard lipid-lowering therapy on post-fat load lipid levels in patients with familial dysbetalipoproteinemia. A randomized placebo-controlled crossover trial

Dietary lipid modification for mild and severe dyslipidaemias

Tracking the ancestry of known and ‘ghost’ homeologous subgenomes in model grass Brachypodium polyploids

Dysbetalipoproteinemia: an extreme disorder of remnant metabolism

Elevated Plasma PCSK9 Level Is Equally Detrimental for Patients With Nonfamilial Hypercholesterolemia and Heterozygous Familial Hypercholesterolemia, Irrespective of Low-Density Lipoprotein Receptor Defects

Colesevelam Hydrochloride: Efficacy and Safety in Pediatric Subjects with Heterozygous Familial Hypercholesterolemia

Proprotein convertase subtilisin/kexin type 9 inhibition

Comparative aspects of the care of familial hypercholesterolemia in the “Ten Countries Study”

Normalization of Low-Density Lipoprotein Receptor Expression in Receptor Defective Homozygous Familial Hypercholesterolemia by Inhibition of PCSK9 With Alirocumab

Translational Research for Improving the Care of Familial Hypercholesterolemia: The “Ten Countries Study” and Beyond

Autosomal dominant familial dysbetalipoproteinemia: A pathophysiological framework and practical approach to diagnosis and therapy

Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation

Cardiovascular risk factors in patients with Addison's disease: a comparative study of South African and Swedish patients

RNA-based therapy in the management of lipid disorders: a review

Tendon xanthomas: Not always familial hypercholesterolemia

PCSK9 inhibition in LDL cholesterol reduction: genetics and therapeutic implications of very low plasma lipoprotein levels

Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia

A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations

Genetic and Mechanistic Insights into the Modulation of Circulating Lipoprotein (a) Concentration by Apolipoprotein E Isoforms

Adiposity and the development of dyslipidemia in APOE ε2 homozygous subjects: A longitudinal analysis in two population-based cohorts

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