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Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development

Signal transduction and targeted therapy, 2021-03, Vol.6 (1), p.134-134, Article 134

2021

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Gender Differences in Patients With COVID-19: Focus on Severity and Mortality

Frontiers in public health, 2020-04, Vol.8, p.152-152

2020

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Berberine is an insulin secretagogue targeting the KCNH6 potassium channel

Nature communications, 2021-09, Vol.12 (1), p.5616-5616, Article 5616

2021

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Angiotensin‐(1‐7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism

The FASEB journal, 2020-12, Vol.34 (12), p.16291-16306

2020

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Response to Comment on Liu et al. Incidence of Type 1 Diabetes May Be Underestimated in the Chinese Population: Evidence From 21.7 Million People Between 2007 and 2017. Diabetes Care 2021;44:2503-2509

Diabetes care, 2022-01, Vol.45 (1), p.e13-e14

2022

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Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes

Acta diabetologica, 2010-09, Vol.47 (3), p.193-199

2010

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Spirulina maxima extract prevents activation of the NLRP3 inflammasome by inhibiting ERK signaling

Scientific reports, 2020-02, Vol.10 (1), p.2075-2075, Article 2075

2020

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Waist-to-height ratio is better than body mass index and waist circumference as a screening criterion for metabolic syndrome in Han Chinese adults

Medicine (Baltimore), 2017-09, Vol.96 (39), p.e8192-e8192

2017

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Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice

Molecules (Basel, Switzerland), 2017-08, Vol.22 (8), p.1363

2017

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Induction of Apoptosis in Human Glioma Cells by Fucoxanthin via Triggering of ROS-Mediated Oxidative Damage and Regulation of MAPKs and PI3K–AKT Pathways

Journal of agricultural and food chemistry, 2019-02, Vol.67 (8), p.2212-2219

2019

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miR-21 overexpression enhances TGF-β1-induced epithelial-to-mesenchymal transition by target smad7 and aggravates renal damage in diabetic nephropathy

Molecular and cellular endocrinology, 2014-07, Vol.392 (1-2), p.163-172

2014

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Angiotensin‐converting enzyme 2 inhibits endoplasmic reticulum stress–associated pathway to preserve nonalcoholic fatty liver disease

Diabetes/metabolism research and reviews, 2019-05, Vol.35 (4), p.e3123-n/a

2019

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ACE2 and energy metabolism: the connection between COVID-19 and chronic metabolic disorders

Clinical science (1979), 2021-02, Vol.135 (3), p.535-554

2021

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Amphiregulin can predict treatment resistance to palliative first-line cetuximab plus FOLFIRI chemotherapy in patients with RAS wild-type metastatic colorectal cancer

Scientific reports, 2021-12, Vol.11 (1), p.23803-23803, Article 23803

2021

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Uncovering the characteristics of the gut microbiota in patients with ischemic stroke and hemorrhagic stroke

Scientific reports, 2024-05, Vol.14 (1), p.11776-11776, Article 11776

2024

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Prevalence and associated factors of diabetic retinopathy in Beijing, China: a cross-sectional study

BMJ open, 2017-08, Vol.7 (8), p.e015473-e015473

2017

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Development of a sensitive and reliable ELISA kit of urinary haptoglobin to predict progress of diabetic kidney disease

Diabetes/metabolism research and reviews, 2021-05, Vol.37 (4), p.e3432-n/a

2021

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Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors

eLife, 2022-12, Vol.11

2022

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Vitamin D deficiency is associated with risk of developing peripheral arterial disease in type 2 diabetic patients

BMC cardiovascular disorders, 2019-06, Vol.19 (1), p.145-145, Article 145

2019

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PI3K-targeting strategy using alpelisib to enhance the antitumor effect of paclitaxel in human gastric cancer

Scientific reports, 2020-07, Vol.10 (1), p.12308-12308, Article 12308

2020

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Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality

eLife, 2024-08, Vol.13

2024

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The ACE2/Ang-(1–7)/Mas axis can inhibit hepatic insulin resistance

Molecular and cellular endocrinology, 2014-08, Vol.393 (1-2), p.30-38

2014

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Incidence of Type 1 Diabetes May Be Underestimated in the Chinese Population: Evidence From 21.7 Million People Between 2007 and 2017

Diabetes care, 2021-11, Vol.44 (11), p.2503-2509

2021

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An approach combining deep learning and molecule docking for drug discovery of cathepsin L

Expert opinion on drug discovery, 2023-03, Vol.18 (3), p.347-356

2023

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High Prevalence of Diabetic Retinopathy in Diabetic Patients Concomitant with Metabolic Syndrome

PloS one, 2016-01, Vol.11 (1), p.e0145293-e0145293

2016

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Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development

Gender Differences in Patients With COVID-19: Focus on Severity and Mortality

Berberine is an insulin secretagogue targeting the KCNH6 potassium channel

Angiotensin‐(1‐7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism

Response to Comment on Liu et al. Incidence of Type 1 Diabetes May Be Underestimated in the Chinese Population: Evidence From 21.7 Million People Between 2007 and 2017. Diabetes Care 2021;44:2503-2509

Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes

Spirulina maxima extract prevents activation of the NLRP3 inflammasome by inhibiting ERK signaling

Waist-to-height ratio is better than body mass index and waist circumference as a screening criterion for metabolic syndrome in Han Chinese adults

Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice

Induction of Apoptosis in Human Glioma Cells by Fucoxanthin via Triggering of ROS-Mediated Oxidative Damage and Regulation of MAPKs and PI3K–AKT Pathways

miR-21 overexpression enhances TGF-β1-induced epithelial-to-mesenchymal transition by target smad7 and aggravates renal damage in diabetic nephropathy

Angiotensin‐converting enzyme 2 inhibits endoplasmic reticulum stress–associated pathway to preserve nonalcoholic fatty liver disease

ACE2 and energy metabolism: the connection between COVID-19 and chronic metabolic disorders

Amphiregulin can predict treatment resistance to palliative first-line cetuximab plus FOLFIRI chemotherapy in patients with RAS wild-type metastatic colorectal cancer

Uncovering the characteristics of the gut microbiota in patients with ischemic stroke and hemorrhagic stroke

Prevalence and associated factors of diabetic retinopathy in Beijing, China: a cross-sectional study

Development of a sensitive and reliable ELISA kit of urinary haptoglobin to predict progress of diabetic kidney disease

Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors

Vitamin D deficiency is associated with risk of developing peripheral arterial disease in type 2 diabetic patients

PI3K-targeting strategy using alpelisib to enhance the antitumor effect of paclitaxel in human gastric cancer

Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality

The ACE2/Ang-(1–7)/Mas axis can inhibit hepatic insulin resistance

Incidence of Type 1 Diabetes May Be Underestimated in the Chinese Population: Evidence From 21.7 Million People Between 2007 and 2017

An approach combining deep learning and molecule docking for drug discovery of cathepsin L

High Prevalence of Diabetic Retinopathy in Diabetic Patients Concomitant with Metabolic Syndrome

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