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Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor

Cancer science, 2017-10, Vol.108 (10), p.2069-2078

2017

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Discovery of novel thieno[2,3- d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure–activity relationships

Bioorganic & medicinal chemistry letters, 2009-01, Vol.19 (2), p.305-308

2009

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Cutting Edge: Role of Toll-Like Receptor 1 in Mediating Immune Response to Microbial Lipoproteins

The Journal of immunology (1950), 2002-07, Vol.169 (1), p.10-14

2002

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Discovery of Novel Thieno[2,3-d]pyrimidin-4-yl Hydrazone-Based Cyclin-Dependent Kinase 4 Inhibitors: Synthesis, Biological Evaluation and Structure–Activity Relationships

Chemical and Pharmaceutical Bulletin, 2011/08/01, Vol.59(8), pp.991-1002

2011

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Severe Duodenal Hemorrhage Induced by Lugol's Solution Administered for Thyroid Crisis Treatment

Internal Medicine, 2010, Vol.49(8), pp.759-761

2010

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Discovery of novel thieno[2,3- d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation and structure–activity relationships. Part 2

Bioorganic & medicinal chemistry, 2009-12, Vol.17 (23), p.7850-7860

2009

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Disappearance of multiple hyperplastic polyps after eradication of Helicobacter pylori

Gastrointestinal endoscopy, 1997-12, Vol.46 (6), p.566-568

1997

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New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 4

Bioorganic & medicinal chemistry, 2003-10, Vol.11 (20), p.4431-4447

2003

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An abdominal follicular dendritic cell tumor in Castleman's disease

Rinshō ketsueki, 2004-09, Vol.45 (9), p.1033

2004

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Changes in serum pepsinogen, gastrin, and immunoglobulin G antibody titers in helicobacter pylori-positive gastric ulcer after eradication of infection

Journal of clinical gastroenterology, 1997-07, Vol.25 (1), p.317-322

1997

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Wilms’ tumor 1-associating protein complex regulates alternative splicing and polyadenylation at potential G-quadruplex-forming splice site sequences

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101248-101248, Article 101248

2021

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Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle

The Journal of biological chemistry, 2013-11, Vol.288 (46), p.33292-33302

2013

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Introduction of sugar-modified nucleotides into CpG-containing antisense oligonucleotides inhibits TLR9 activation

Scientific reports, 2024-05, Vol.14 (1), p.11540-11540, Article 11540

2024

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A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese

PLoS genetics, 2012-01, Vol.8 (1), p.e1002455-e1002455

2012

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Long‐term outcomes of esophageal squamous cell carcinoma with invasion depth of pathological T1a‐muscularis mucosae and T1b‐submucosa by endoscopic resection followed by appropriate additional treatment

Digestive endoscopy, 2022-05, Vol.34 (4), p.793-804

2022

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Synthesis of natural product-like polyprenylated phenols and quinones: Evaluation of their neuroprotective activities

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115156, Article 115156

2020

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Diagnostic and prognostic biomarkers for progressive fibrosing interstitial lung disease

PloS one, 2023-03, Vol.18 (3), p.e0283288-e0283288

2023

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A successful antimicrobial therapeutic strategy for the discitis caused by Aggregatibacter actinomycetemcomitans under unknown drug susceptibility: A case report

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2018-10, Vol.24 (10), p.849-851

2018

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Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4

Biochemical and biophysical research communications, 2016-01, Vol.469 (4), p.797-802

2016

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Long-term outcomes of combined endoscopic resection and chemoradiotherapy for esophageal squamous cell carcinoma with submucosal invasion

Digestive and liver disease, 2018-08, Vol.50 (8), p.833-838

2018

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Vascular Endothelial Growth Factor- and Thrombin-induced Termination Factor, Down Syndrome Critical Region-1, Attenuates Endothelial Cell Proliferation and Angiogenesis

The Journal of biological chemistry, 2004-11, Vol.279 (48), p.50537-50554

2004

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Triptan-induced Reversible Cerebral Vasoconstriction Syndrome: Two Case Reports with a Literature Review

Internal Medicine, 2016/12/01, Vol.55(23), pp.3525-3528

2016

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Therapeutic response of patients with adult Still’s disease to biologic agents: multicenter results in Japan

Modern rheumatology, 2012-09, Vol.22 (5), p.712-719

2012

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The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix

EMBO reports, 2011-05, Vol.12 (5), p.451-457

2011

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Cigarette smoking, alcohol consumption, and risk of systemic lupus erythematosus: a case-control study in a Japanese population

Journal of rheumatology, 2012-07, Vol.39 (7), p.1363-1370

2012

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Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor

Discovery of novel thieno[2,3- d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure–activity relationships

Cutting Edge: Role of Toll-Like Receptor 1 in Mediating Immune Response to Microbial Lipoproteins

Discovery of Novel Thieno[2,3-d]pyrimidin-4-yl Hydrazone-Based Cyclin-Dependent Kinase 4 Inhibitors: Synthesis, Biological Evaluation and Structure–Activity Relationships

Severe Duodenal Hemorrhage Induced by Lugol's Solution Administered for Thyroid Crisis Treatment

Discovery of novel thieno[2,3- d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation and structure–activity relationships. Part 2

Disappearance of multiple hyperplastic polyps after eradication of Helicobacter pylori

New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 4

An abdominal follicular dendritic cell tumor in Castleman's disease

Changes in serum pepsinogen, gastrin, and immunoglobulin G antibody titers in helicobacter pylori-positive gastric ulcer after eradication of infection

Wilms’ tumor 1-associating protein complex regulates alternative splicing and polyadenylation at potential G-quadruplex-forming splice site sequences

Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle

Introduction of sugar-modified nucleotides into CpG-containing antisense oligonucleotides inhibits TLR9 activation

A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese

Long‐term outcomes of esophageal squamous cell carcinoma with invasion depth of pathological T1a‐muscularis mucosae and T1b‐submucosa by endoscopic resection followed by appropriate additional treatment

Synthesis of natural product-like polyprenylated phenols and quinones: Evaluation of their neuroprotective activities

Diagnostic and prognostic biomarkers for progressive fibrosing interstitial lung disease

A successful antimicrobial therapeutic strategy for the discitis caused by Aggregatibacter actinomycetemcomitans under unknown drug susceptibility: A case report

Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4

Long-term outcomes of combined endoscopic resection and chemoradiotherapy for esophageal squamous cell carcinoma with submucosal invasion

Vascular Endothelial Growth Factor- and Thrombin-induced Termination Factor, Down Syndrome Critical Region-1, Attenuates Endothelial Cell Proliferation and Angiogenesis

Triptan-induced Reversible Cerebral Vasoconstriction Syndrome: Two Case Reports with a Literature Review

Therapeutic response of patients with adult Still’s disease to biologic agents: multicenter results in Japan

The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix

Cigarette smoking, alcohol consumption, and risk of systemic lupus erythematosus: a case-control study in a Japanese population

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