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Global Identification of Modular Cullin-RING Ligase Substrates

Cell, 2011-10, Vol.147 (2), p.459-474

2011

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FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

Cell reports (Cambridge), 2019-03, Vol.26 (11), p.3076-3086.e6

2019

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Dissenting degradation: Deubiquitinases in cell cycle and cancer

Seminars in cancer biology, 2020-12, Vol.67 (Pt 2), p.145-158

2020

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VprBP/DCAF1 Regulates the Degradation and Nonproteolytic Activation of the Cell Cycle Transcription Factor FoxM1

Molecular and cellular biology, 2017-07, Vol.37 (13)

2017

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A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells

eLife, 2014-03, Vol.3, p.e01630-e01630

2014

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Inhibition of CDK1 by RO-3306 Exhibits Anti-Tumorigenic Effects in Ovarian Cancer Cells and a Transgenic Mouse Model of Ovarian Cancer

International journal of molecular sciences, 2023-08, Vol.24 (15), p.12375

2023

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The E3 Ubiquitin Ligase SCF(Cyclin F) Transmits AKT Signaling to the Cell-Cycle Machinery

Cell reports (Cambridge), 2017-09, Vol.20 (13), p.3212-3222

2017

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Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton

Cell reports (Cambridge), 2024-08, Vol.43 (8), p.114510-114510, Article 114510

2024

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Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (24), p.9845-9850

2011

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Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

eLife, 2021-12, Vol.10

2021

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In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

PLoS biology, 2020-12, Vol.18 (12), p.e3000975-e3000975

2020

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Chlamydia trachomatis-Induced Alterations in the Host Cell Proteome Are Required for Intracellular Growth

Cell host & microbe, 2014-01, Vol.15 (1), p.113-124

2014

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Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (52), p.E3659-E3667

2012

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Impressionist portraits of mitotic exit: APC/C, K11-linked ubiquitin chains and Cezanne

Cell cycle (Georgetown, Tex.), 2019-04, Vol.18 (6-7), p.652-660

2019

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A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

Cell, 2009-05, Vol.137 (5), p.835-848

2009

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Cezanne/OTUD7B is a cell cycle‐regulated deubiquitinase that antagonizes the degradation of APC/C substrates

The EMBO journal, 2018-08, Vol.37 (16), p.n/a

2018

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The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome

The Journal of biological chemistry, 2017-07, Vol.292 (30), p.12503-12515

2017

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Nucleolar and spindle-associated protein 1 (NUSAP1) interacts with a SUMO E3 ligase complex during chromosome segregation

The Journal of biological chemistry, 2017-10, Vol.292 (42), p.17178-17189

2017

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Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming

Nature structural & molecular biology, 2020-06, Vol.27 (6), p.550-560

2020

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Functional conservation and divergence of the helix‐turn‐helix motif of E2 ubiquitin‐conjugating enzymes

The EMBO journal, 2022-02, Vol.41 (3), p.e108823-n/a

2022

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Mass spectrometry–based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells

The Journal of biological chemistry, 2020-02, Vol.295 (8), p.2359-2374

2020

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Elucidating Human Mitosis Using an Anaphase-Like Cell-Free System

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2329, p.143

2021

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APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry

Cell reports (Cambridge), 2016-09, Vol.16 (12), p.3359-3372

2016

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Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C)

Nature structural & molecular biology, 2023-11, Vol.30 (11), p.1663-1674

2023

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4-1BB-encoding CAR causes cell death via sequestration of the ubiquitin-modifying enzyme A20

Cellular & molecular immunology, 2024-08, Vol.21 (8), p.905-917

2024

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Global Identification of Modular Cullin-RING Ligase Substrates

FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

Dissenting degradation: Deubiquitinases in cell cycle and cancer

VprBP/DCAF1 Regulates the Degradation and Nonproteolytic Activation of the Cell Cycle Transcription Factor FoxM1

A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells

Inhibition of CDK1 by RO-3306 Exhibits Anti-Tumorigenic Effects in Ovarian Cancer Cells and a Transgenic Mouse Model of Ovarian Cancer

The E3 Ubiquitin Ligase SCF(Cyclin F) Transmits AKT Signaling to the Cell-Cycle Machinery

Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton

Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

Chlamydia trachomatis-Induced Alterations in the Host Cell Proteome Are Required for Intracellular Growth

Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells

Impressionist portraits of mitotic exit: APC/C, K11-linked ubiquitin chains and Cezanne

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

Cezanne/OTUD7B is a cell cycle‐regulated deubiquitinase that antagonizes the degradation of APC/C substrates

The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome

Nucleolar and spindle-associated protein 1 (NUSAP1) interacts with a SUMO E3 ligase complex during chromosome segregation

Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming

Functional conservation and divergence of the helix‐turn‐helix motif of E2 ubiquitin‐conjugating enzymes

Mass spectrometry–based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells

Elucidating Human Mitosis Using an Anaphase-Like Cell-Free System

APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry

Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C)

4-1BB-encoding CAR causes cell death via sequestration of the ubiquitin-modifying enzyme A20

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