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The structural and biochemical foundations of thiamin biosynthesis

Annual review of biochemistry, 2009-01, Vol.78 (1), p.569-603

2009

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Towards the structural characterization of the human methyltransferome

Current opinion in structural biology, 2018-12, Vol.53, p.12-21

2018

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Structure of human desArg-C5a

Acta crystallographica. Section D, Biological crystallography., 2010-02, Vol.66 (2), p.190-197

2010

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Radical S-Adenosylmethionine (SAM) Enzymes in Cofactor Biosynthesis: A Treasure Trove of Complex Organic Radical Rearrangement Reactions

The Journal of biological chemistry, 2015-02, Vol.290 (7), p.3980-3986

2015

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Structural biology of S-adenosylmethionine decarboxylase

Amino acids, 2010-02, Vol.38 (2), p.451-460

2010

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Biochemical and structural characterization of Klebsiella pneumoniae oxamate amidohydrolase in the uric acid degradation pathway

Acta crystallographica. Section D, Structural biology, 2016-06, Vol.72 (6), p.808-816

2016

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Structural analyses reveal two distinct families of nucleoside phosphorylases

Biochemical journal, 2002-01, Vol.361 (Pt 1), p.1-25

2002

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The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors

Cancer chemotherapy and pharmacology, 2020-03, Vol.85 (3), p.573-583

2020

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Evolutionary Links as Revealed by the Structure of Thermotoga maritima S-Adenosylmethionine Decarboxylase

The Journal of biological chemistry, 2004-08, Vol.279 (32), p.33837-33846

2004

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Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding

Journal of molecular biology, 2000-05, Vol.298 (5), p.875-893

2000

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Structure of Human Phosphopantothenoylcysteine Synthetase at 2.3 Å Resolution

Structure (London), 2003-08, Vol.11 (8), p.927-936

2003

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Identification of a Subversive Substrate of Trichomonas vaginalis Purine Nucleoside Phosphorylase and the Crystal Structure of the Enzyme-Substrate Complex

The Journal of biological chemistry, 2005-06, Vol.280 (23), p.22318-22325

2005

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Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design

Biochemistry (Easton), 2004-05, Vol.43 (18), p.5159-5169

2004

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Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase

Journal of molecular biology, 2011-07, Vol.410 (3), p.447-460

2011

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Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase

Biochemistry (Easton), 2008-12, Vol.47 (50), p.13404-13417

2008

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Structure of Human Adenosine Kinase at 1.5 Å Resolution

Biochemistry (Easton), 1998-11, Vol.37 (45), p.15607-15620

1998

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Glycal Formation in Crystals of Uridine Phosphorylase

Biochemistry (Easton), 2010-04, Vol.49 (16), p.3499-3509

2010

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Binding and inhibition of human spermidine synthase by decarboxylated S‐adenosylhomocysteine

Protein science, 2011-11, Vol.20 (11), p.1836-1844

2011

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Role of the Sulfonium Center in Determining the Ligand Specificity of Human S-Adenosylmethionine Decarboxylase

Biochemistry (Easton), 2009-07, Vol.48 (27), p.6423-6430

2009

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The Crystal Structure of 5′-Deoxy-5′-methylthioadenosine Phosphorylase II from Sulfolobus solfataricus, a Thermophilic Enzyme Stabilized by Intramolecular Disulfide Bonds

Journal of molecular biology, 2006-03, Vol.357 (1), p.252-262

2006

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PNP anticancer gene therapy

Current topics in medicinal chemistry, 2005-10, Vol.5 (13), p.1259-1274

2005

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Purine Nucleoside Phosphorylase. 2. Catalytic Mechanism

Biochemistry (Easton), 1997-09, Vol.36 (39), p.11735-11748

1997

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The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation

Acta crystallographica. Section D, Biological crystallography., 2006-02, Vol.62 (2), p.133-139

2006

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Calf Spleen Purine Nucleoside Phosphorylase Complexed with Substrates and Substrate Analogues

Biochemistry (Easton), 1998-05, Vol.37 (20), p.7135-7146

1998

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Structural and kinetic insights into the mechanism of 5-hydroxyisourate hydrolase from Klebsiella pneumoniae

Acta crystallographica. Section D, Biological crystallography., 2011-08, Vol.67 (8), p.671-677

2011

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The structural and biochemical foundations of thiamin biosynthesis

Towards the structural characterization of the human methyltransferome

Structure of human desArg-C5a

Radical S-Adenosylmethionine (SAM) Enzymes in Cofactor Biosynthesis: A Treasure Trove of Complex Organic Radical Rearrangement Reactions

Structural biology of S-adenosylmethionine decarboxylase

Biochemical and structural characterization of Klebsiella pneumoniae oxamate amidohydrolase in the uric acid degradation pathway

Structural analyses reveal two distinct families of nucleoside phosphorylases

The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors

Evolutionary Links as Revealed by the Structure of Thermotoga maritima S-Adenosylmethionine Decarboxylase

Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding

Structure of Human Phosphopantothenoylcysteine Synthetase at 2.3 Å Resolution

Identification of a Subversive Substrate of Trichomonas vaginalis Purine Nucleoside Phosphorylase and the Crystal Structure of the Enzyme-Substrate Complex

Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design

Characterization of the Structure and Function of Klebsiella pneumoniae Allantoin Racemase

Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase

Structure of Human Adenosine Kinase at 1.5 Å Resolution

Glycal Formation in Crystals of Uridine Phosphorylase

Binding and inhibition of human spermidine synthase by decarboxylated S‐adenosylhomocysteine

Role of the Sulfonium Center in Determining the Ligand Specificity of Human S-Adenosylmethionine Decarboxylase

The Crystal Structure of 5′-Deoxy-5′-methylthioadenosine Phosphorylase II from Sulfolobus solfataricus, a Thermophilic Enzyme Stabilized by Intramolecular Disulfide Bonds

PNP anticancer gene therapy

Purine Nucleoside Phosphorylase. 2. Catalytic Mechanism

The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation

Calf Spleen Purine Nucleoside Phosphorylase Complexed with Substrates and Substrate Analogues

Structural and kinetic insights into the mechanism of 5-hydroxyisourate hydrolase from Klebsiella pneumoniae

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