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Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy

The Journal of cell biology, 2020-09, Vol.219 (9), p.1

2020

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Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates

Pharmaceutical research, 2022-01, Vol.39 (1), p.89-103

2022

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Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (20), p.4865-4869

2016

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Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

Oncogene, 2020-05, Vol.39 (19), p.3867-3878

2020

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Development of Photoswitchable Estrogen Receptor Ligands

Chemical and Pharmaceutical Bulletin, 2020/04/01, Vol.68(4), pp.398-402

2020

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Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating foldamers for efficient siRNA delivery

Chemical communications (Cambridge, England), 2019-07, Vol.55 (54), p.7792-7795

2019

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Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells

Cancer science, 2013-11, Vol.104 (11), p.1492-1498

2013

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Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15868-15882

2021

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Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication

Journal of pharmacological sciences, 2022-07, Vol.149 (3), p.81-84

2022

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A Helix-Stabilized Cell-Penetrating Peptide as an Intracellular Delivery Tool

Chembiochem : a European journal of chemical biology, 2016-01, Vol.17 (2), p.137-140

2016

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Protocols for Synthesis of SNIPERs and the Methods to Evaluate the Anticancer Effects

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2365, p.331

2021

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Efficient synthesis of a multi-substituted diphenylmethane skeleton as a steroid mimetic

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (11), p.2590-2593

2017

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Temperature-Dependent Formation of N-Nitrosodimethylamine during the Storage of Ranitidine Reagent Powders and Tablets

Chemical and Pharmaceutical Bulletin, 2020/10/01, Vol.68(10), pp.1008-1012

2020

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Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids

Bioorganic & medicinal chemistry, 2016-06, Vol.24 (12), p.2681-2687

2016

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Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules

Molecular pharmacology, 2017-03, Vol.91 (3), p.159-166

2017

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Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1793-1796

2012

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Development of an ON/OFF switchable fluorescent probe targeting His tag fused proteins in living cells

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (15), p.3417-3422

2017

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Simple and efficient knockdown of His-tagged proteins by ternary molecules consisting of a His-tag ligand, a ubiquitin ligase ligand, and a cell-penetrating peptide

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (18), p.4478-4481

2017

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Synthesis and evaluation of raloxifene derivatives as a selective estrogen receptor down-regulator

Bioorganic & medicinal chemistry, 2016-07, Vol.24 (13), p.2914-2919

2016

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Structural development of non-secosteroidal vitamin D receptor (VDR) ligands without any asymmetric carbon

Bioorganic & medicinal chemistry, 2018-12, Vol.26 (23-24), p.6146-6152

2018

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Synthesis and Evaluation of Novel Carbocyclic Oxetanocin A (COA-Cl) Derivatives as Potential Tube Formation Agents

Chemical and Pharmaceutical Bulletin, 2015/09/01, Vol.63(9), pp.701-709

2015

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Identification of Mutaprodenafil in a Dietary Supplement and Its Subsequent Synthesis

Chemical and Pharmaceutical Bulletin, 2011/10/01, Vol.59(10), pp.1314-1316

2011

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Synthesis and evaluation of novel 3-(3,5-dimethylbenzyl)uracil analogs as potential anti-HIV-1 agents

Bioorganic & medicinal chemistry, 2013-09, Vol.21 (18), p.5900-5906

2013

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Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives

Antiviral chemistry & chemotherapy, 2015-04, Vol.24 (2), p.62-71

2015

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Effects of alkyl side chains and terminal hydrophilicity on vitamin D receptor (VDR) agonistic activity based on the diphenylpentane skeleton

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (22), p.5362-5366

2015

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Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy

Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates

Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

Development of Photoswitchable Estrogen Receptor Ligands

Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating foldamers for efficient siRNA delivery

Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells

Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design

Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication

A Helix-Stabilized Cell-Penetrating Peptide as an Intracellular Delivery Tool

Protocols for Synthesis of SNIPERs and the Methods to Evaluate the Anticancer Effects

Efficient synthesis of a multi-substituted diphenylmethane skeleton as a steroid mimetic

Temperature-Dependent Formation of N-Nitrosodimethylamine during the Storage of Ranitidine Reagent Powders and Tablets

Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acids

Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules

Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Development of an ON/OFF switchable fluorescent probe targeting His tag fused proteins in living cells

Simple and efficient knockdown of His-tagged proteins by ternary molecules consisting of a His-tag ligand, a ubiquitin ligase ligand, and a cell-penetrating peptide

Synthesis and evaluation of raloxifene derivatives as a selective estrogen receptor down-regulator

Structural development of non-secosteroidal vitamin D receptor (VDR) ligands without any asymmetric carbon

Synthesis and Evaluation of Novel Carbocyclic Oxetanocin A (COA-Cl) Derivatives as Potential Tube Formation Agents

Identification of Mutaprodenafil in a Dietary Supplement and Its Subsequent Synthesis

Synthesis and evaluation of novel 3-(3,5-dimethylbenzyl)uracil analogs as potential anti-HIV-1 agents

Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives

Effects of alkyl side chains and terminal hydrophilicity on vitamin D receptor (VDR) agonistic activity based on the diphenylpentane skeleton

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