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Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC−MS/MS

Analytical chemistry (Washington), 2003-07, Vol.75 (13), p.3019-3030

2003

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Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

Analytical chemistry (Washington), 1998-03, Vol.70 (5), p.882-889

1998

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Quantitative liquid chromatographic and tandem mass spectrometric determination of vitamin D₃ in human serum with derivatization: A comparison of in-tube LLE, 96-well plate LLE and in-tip SPME

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-05, Vol.879 (17-18), p.1457-1466

2011

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Determination of dextromethorphan and its metabolite dextrorphan in human urine using high performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry: a study of selectivity of a tandem mass spectrometric assay

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-02, Vol.816 (1), p.297-308

2005

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Simultaneous determination of Aprepitant and two metabolites in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

Journal of pharmaceutical and biomedical analysis, 2004-09, Vol.35 (5), p.1213-1229

2004

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Determination of a novel substance P inhibitor in human plasma by high-performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometric detection using single and triple quadrupole detectors

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-08, Vol.807 (2), p.243-250

2004

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Determination of efavirenz, a selective non-nucleoside reverse transcriptase inhibitor, in human plasma using HPLC with post-column photochemical derivatization and fluorescence detection

Journal of pharmaceutical and biomedical analysis, 2002-06, Vol.28 (5), p.925-934

2002

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Determination of a cyclooxygenase II inhibitor in human plasma by capillary gas chromatography with mass spectrometric detection

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-06, Vol.805 (1), p.21-25

2004

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Determination of a thermally labile metabolite of a novel growth hormone secretagogue in human and dog plasma by liquid chromatography with ion spray tandem mass spectrometric detection

Journal of chromatography. B, Biomedical sciences and applications, 2001-08, Vol.760 (1), p.45-53

2001

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Low level determination of dorzolamide and its de-ethylated metabolite in human plasma by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 1997-04, Vol.15 (7), p.1001-1008

1997

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Pharmacokinetics of Aprepitant After Single and Multiple Oral Doses in Healthy Volunteers

Journal of clinical pharmacology, 2006-03, Vol.46 (3), p.291-300

2006

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Cyclobenzaprine Pharmacokinetics, Including the Effects of Age, Gender, and Hepatic Insufficiency

Journal of clinical pharmacology, 2002-01, Vol.42 (1), p.61-69

2002

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Determination of a substance P antagonist in human plasma and urine using high-performance liquid chromatography with ultraviolet absorbance and tandem mass spectrometric detection

Journal of pharmaceutical and biomedical analysis, 1997-06, Vol.15 (9), p.1427-1433

1997

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Effects of aprepitant on cytochrome P450 3A4 activity using midazolam as a probe

Clinical pharmacology and therapeutics, 2003-08, Vol.74 (2), p.150-156

2003

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Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant

Biological psychiatry (1969), 2004-05, Vol.55 (10), p.1007-1012

2004

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Determination of pirenzepine in human plasma using liquid chromatography with tandem mass spectrometric detection

Journal of pharmaceutical and biomedical analysis, 1995-08, Vol.13 (9), p.1179-1184

1995

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Effect of MK-386, a novel inhibitor of type 1 5α- reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men

The journal of clinical endocrinology and metabolism, 1996-08, Vol.81 (8), p.2942-2947

1996

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Bioavailability of alendronate and vitamin D(3) in an alendronate/vitamin D(3) combination tablet

Journal of clinical pharmacology, 2011-10, Vol.51 (10), p.1439-1448

2011

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Effect of impaired renal function and haemodialysis on the pharmacokinetics of aprepitant

Clinical pharmacokinetics, 2005-01, Vol.44 (6), p.637-647

2005

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Indirect chiral separation and analyses in human biological fluids of the stereoisomers of a thienothiopyran-2-sulfonamide (TRUSOPT), a novel carbonic anhydrase inhibitor with two chiral centers in the molecule

Chirality (New York, N.Y.), 1992, Vol.4 (8), p.515-519

1992

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Determination of a glycine/NMDA receptor antagonist in human plasma and urine using column-switching high-performance liquid chromatography with ultraviolet, fluorescence and tandem mass spectrometric detection

Journal of Pharmaceutical and Biomedical Analysis [J. PHARM. BIOMED. ANAL.]. Vol. 13, no. 10. 1995, 1995-09, Vol.13 (10), p.1215-1223

1995

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Determination of Rofecoxib (MK-0966), a cyclooxygenase-2 inhibitor, in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

Journal of chromatography. B, Biomedical sciences and applications, 2000-10, Vol.748 (1), p.31-39

2000

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Analytical chiral separation of the stereoisomers of a novel carbonic anhydrase inhibitor and its deethylated metabolite, and the assignment of absolute configuration of the human metabolite and chiral degradation products

Pharmaceutical research, 1994-03, Vol.11 (3), p.449-454

1994

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Simultaneous determination of L-693,612, a topical carbonic anhydrase inhibitor, and two potential metabolites in human whole blood by ion-pair high-performance liquid chromatography

Journal of Chromatography A, 1994-02, Vol.660 (1), p.307-312

1994

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Development of high-performance liquid chromatography–tandem mass spectrometric methods for the determination of a new oxytocin receptor antagonist (L-368,899) extracted from human plasma and urine: a case of lack of specificity due to the presence of metabolites

Journal of chromatography. B, Biomedical sciences and applications, 1998-09, Vol.716 (1), p.195-208

1998

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Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC−MS/MS

Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

Quantitative liquid chromatographic and tandem mass spectrometric determination of vitamin D₃ in human serum with derivatization: A comparison of in-tube LLE, 96-well plate LLE and in-tip SPME

Determination of dextromethorphan and its metabolite dextrorphan in human urine using high performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry: a study of selectivity of a tandem mass spectrometric assay

Simultaneous determination of Aprepitant and two metabolites in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

Determination of a novel substance P inhibitor in human plasma by high-performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometric detection using single and triple quadrupole detectors

Determination of efavirenz, a selective non-nucleoside reverse transcriptase inhibitor, in human plasma using HPLC with post-column photochemical derivatization and fluorescence detection

Determination of a cyclooxygenase II inhibitor in human plasma by capillary gas chromatography with mass spectrometric detection

Determination of a thermally labile metabolite of a novel growth hormone secretagogue in human and dog plasma by liquid chromatography with ion spray tandem mass spectrometric detection

Low level determination of dorzolamide and its de-ethylated metabolite in human plasma by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry

Pharmacokinetics of Aprepitant After Single and Multiple Oral Doses in Healthy Volunteers

Cyclobenzaprine Pharmacokinetics, Including the Effects of Age, Gender, and Hepatic Insufficiency

Determination of a substance P antagonist in human plasma and urine using high-performance liquid chromatography with ultraviolet absorbance and tandem mass spectrometric detection

Effects of aprepitant on cytochrome P450 3A4 activity using midazolam as a probe

Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant

Determination of pirenzepine in human plasma using liquid chromatography with tandem mass spectrometric detection

Effect of MK-386, a novel inhibitor of type 1 5α- reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men

Bioavailability of alendronate and vitamin D(3) in an alendronate/vitamin D(3) combination tablet

Effect of impaired renal function and haemodialysis on the pharmacokinetics of aprepitant

Indirect chiral separation and analyses in human biological fluids of the stereoisomers of a thienothiopyran-2-sulfonamide (TRUSOPT), a novel carbonic anhydrase inhibitor with two chiral centers in the molecule

Determination of a glycine/NMDA receptor antagonist in human plasma and urine using column-switching high-performance liquid chromatography with ultraviolet, fluorescence and tandem mass spectrometric detection

Determination of Rofecoxib (MK-0966), a cyclooxygenase-2 inhibitor, in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

Analytical chiral separation of the stereoisomers of a novel carbonic anhydrase inhibitor and its deethylated metabolite, and the assignment of absolute configuration of the human metabolite and chiral degradation products

Simultaneous determination of L-693,612, a topical carbonic anhydrase inhibitor, and two potential metabolites in human whole blood by ion-pair high-performance liquid chromatography

Development of high-performance liquid chromatography–tandem mass spectrometric methods for the determination of a new oxytocin receptor antagonist (L-368,899) extracted from human plasma and urine: a case of lack of specificity due to the presence of metabolites

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