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AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models

Molecular cancer therapeutics, 2007-08, Vol.6 (8), p.2209-2219

2007

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Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2264-2273

2010

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CD86 expression as a surrogate cellular biomarker for pharmacological inhibition of the histone demethylase lysine-specific demethylase 1

Analytical biochemistry, 2013-11, Vol.442 (1), p.104-106

2013

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Pelvic congestion syndrome: Early clinical results after transcatheter ovarian vein embolization

Journal of vascular surgery, 1998-11, Vol.28 (5), p.862-868

1998

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Genomics and the search for novel biomarkers in toxicology

Biomarkers, 2003-03, Vol.8 (2), p.79-92

2003

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Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells

Journal of medicinal chemistry, 2016-12, Vol.59 (24), p.11120-11137

2016

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Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors To Explore a MEK Resistance Hypothesis

Journal of medicinal chemistry, 2015-03, Vol.58 (6), p.2834-2844

2015

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Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome

Cellular and molecular life sciences : CMLS, 2016-02, Vol.73 (4), p.883-900

2016

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Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells

The Journal of immunology (1950), 2017-10, Vol.199 (8), p.2652-2667

2017

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Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Blood, 2022-10, Vol.140 (17), p.1875-1890

2022

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Detection of high-risk human papillomavirus infection in tonsillar specimens using 2 commercially available assays

Diagnostic microbiology and infectious disease, 2016-12, Vol.86 (4), p.365-368

2016

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RSV604, a Novel Inhibitor of Respiratory Syncytial Virus Replication

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3346-3353

2007

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Detection of Smallpox Virus DNA by LightCycler PCR

Journal of Clinical Microbiology, 2002-06, Vol.40 (6), p.1985-1988

2002

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Frequency of isolation of Staphylococcus lugdunensis among staphylococcal isolates causing endocarditis : a 20-year experience

Journal of clinical microbiology, 2000-11, Vol.38 (11), p.4262-4263

2000

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Quantitative Real-Time Polymerase Chain Reaction for Evaluating DNAemia due to Cytomegalovirus, Epstein-Barr Virus, and BK Virus in Solid-Organ Transplant Recipients

Clinical infectious diseases, 2007-10, Vol.45 (8), p.1056-1061

2007

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Detection of Herpes Simplex Virus DNA in Genital and Dermal Specimens by LightCycler PCR after Extraction using the IsoQuick, MagNA Pure, and BioRobot 9604 Methods

Journal of Clinical Microbiology, 2001-06, Vol.39 (6), p.2233-2236

2001

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Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort

The Lancet (British edition), 2024-03, Vol.403 (10433), p.1279-1289

2024

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Engagement of the EP₂ prostanoid receptor closes the K⁺ channel KCa3.1 in human lung mast cells and attenuates their migration

European journal of immunology, 2008-09, Vol.38 (9), p.2548-2556

2008

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Determination of 16S rRNA Sequences of Enterococci and Application to Species Identification of Nonmotile Enterococcus gallinarum Isolates

Journal of Clinical Microbiology, 1998-11, Vol.36 (11), p.3399-3407

1998

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A randomized comparative trial of continued abacavir/lamivudine plus efavirenz or replacement with efavirenz/emtricitabine/tenofovir DF in hypercholesterolemic HIV-1 infected individuals

PloS one, 2015-02, Vol.10 (2), p.e0116297

2015

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A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies

Breast cancer research and treatment, 2016-02, Vol.155 (3), p.521-530

2016

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Bronchoscopy in Ventilator-associated Pneumonia: Agreement of Calibrated Loop and Serial Dilution

American journal of respiratory and critical care medicine, 2006-06, Vol.173 (11), p.1229-1232

2006

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Application of Rapid-Cycle Real-Time Polymerase Chain Reaction for the Detection of Microbial Pathogens: The Mayo-Roche Rapid Anthrax Test

Mayo Clinic proceedings, 2002-07, Vol.77 (7), p.673-680

2002

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Characteristics of a prevalent vertebral deformity predict subsequent vertebral fracture: results from the European Prospective Osteoporosis Study (EPOS)

Bone (New York, N.Y.), 2003-10, Vol.33 (4), p.505-513

2003

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Detection of Vaccinia Virus, Herpes Simplex Virus, Varicella-Zoster Virus, and Bacillus anthracis DNA by LightCycler Polymerase Chain Reaction After Autoclaving: Implications for Biosafety of Bioterrorism Agents

Mayo Clinic proceedings, 2002-07, Vol.77 (7), p.624-628

2002

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AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models

Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

CD86 expression as a surrogate cellular biomarker for pharmacological inhibition of the histone demethylase lysine-specific demethylase 1

Pelvic congestion syndrome: Early clinical results after transcatheter ovarian vein embolization

Genomics and the search for novel biomarkers in toxicology

Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells

Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors To Explore a MEK Resistance Hypothesis

Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome

Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

Detection of high-risk human papillomavirus infection in tonsillar specimens using 2 commercially available assays

RSV604, a Novel Inhibitor of Respiratory Syncytial Virus Replication

Detection of Smallpox Virus DNA by LightCycler PCR

Frequency of isolation of Staphylococcus lugdunensis among staphylococcal isolates causing endocarditis : a 20-year experience

Quantitative Real-Time Polymerase Chain Reaction for Evaluating DNAemia due to Cytomegalovirus, Epstein-Barr Virus, and BK Virus in Solid-Organ Transplant Recipients

Detection of Herpes Simplex Virus DNA in Genital and Dermal Specimens by LightCycler PCR after Extraction using the IsoQuick, MagNA Pure, and BioRobot 9604 Methods

Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort

Engagement of the EP₂ prostanoid receptor closes the K⁺ channel KCa3.1 in human lung mast cells and attenuates their migration

Determination of 16S rRNA Sequences of Enterococci and Application to Species Identification of Nonmotile Enterococcus gallinarum Isolates

A randomized comparative trial of continued abacavir/lamivudine plus efavirenz or replacement with efavirenz/emtricitabine/tenofovir DF in hypercholesterolemic HIV-1 infected individuals

A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies

Bronchoscopy in Ventilator-associated Pneumonia: Agreement of Calibrated Loop and Serial Dilution

Application of Rapid-Cycle Real-Time Polymerase Chain Reaction for the Detection of Microbial Pathogens: The Mayo-Roche Rapid Anthrax Test

Characteristics of a prevalent vertebral deformity predict subsequent vertebral fracture: results from the European Prospective Osteoporosis Study (EPOS)

Detection of Vaccinia Virus, Herpes Simplex Virus, Varicella-Zoster Virus, and Bacillus anthracis DNA by LightCycler Polymerase Chain Reaction After Autoclaving: Implications for Biosafety of Bioterrorism Agents

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