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Recent Advances of SHP2 Inhibitors in Cancer Therapy: Current Development and Clinical Application

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.11368-11396

2020

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Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.941-964

2019

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Exosomal microRNA‐16‐5p from human urine‐derived stem cells ameliorates diabetic nephropathy through protection of podocyte

Journal of cellular and molecular medicine, 2021-12, Vol.25 (23), p.10798-10813

2021

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Discovery of SHP2-D26 as a First, Potent, and Effective PROTAC Degrader of SHP2 Protein

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7510-7528

2020

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Review of hair follicle dermal cells

Journal of dermatological science, 2010-01, Vol.57 (1), p.2-11

2010

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Roles of NLRP3 inflammasome in intervertebral disc degeneration

Osteoarthritis and cartilage, 2021-06, Vol.29 (6), p.793-801

2021

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CRISPR-Cas12-based detection of SARS-CoV-2

Nature biotechnology, 2020-07, Vol.38 (7), p.870-874

2020

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Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.448-466

2019

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A Dual‐Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis

Advanced materials (Weinheim), 2023-03, Vol.35 (11), p.e2209379-n/a

2023

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The assembly of succinate dehydrogenase: a key enzyme in bioenergetics

Cellular and molecular life sciences : CMLS, 2019-10, Vol.76 (20), p.4023-4042

2019

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Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapy: Progress and Challenges

Cold Spring Harbor perspectives in medicine, 2017-05, Vol.7 (5), p.a026245

2017

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Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6685-6704

2018

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Life Satisfaction and the Pursuit of Happiness on Twitter

PloS one, 2016-03, Vol.11 (3), p.e0150881-e0150881

2016

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Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands

Journal of medicinal chemistry, 2019-12, Vol.62 (24), p.11218-11231

2019

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Non-coding RNAs as regulators in epigenetics

Oncology reports, 2017-01, Vol.37 (1), p.3-9

2017

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Improving dengue fever predictions in Taiwan based on feature selection and random forests

BMC infectious diseases, 2024-03, Vol.24 (Suppl 2), p.334-334, Article 334

2024

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Comparative Analyses of the Conformational Dynamics Between the Soluble and Membrane-Bound Cytokine Receptors

Scientific reports, 2020-05, Vol.10 (1), p.7399-7399, Article 7399

Yang, Chao-Yie

2020

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Inhibition of microRNA‐327 ameliorates ischemia/reperfusion injury‐induced cardiomyocytes apoptosis through targeting apoptosis repressor with caspase recruitment domain

Journal of cellular physiology, 2020-04, Vol.235 (4), p.3753-3767

2020

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Role of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective

World journal of gastroenterology : WJG, 2016-09, Vol.22 (33), p.7463-7477

2016

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Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California

Science (American Association for the Advancement of Science), 2020-07, Vol.369 (6503), p.582-587

2020

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Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

Cell research, 2014-01, Vol.24 (1), p.105-121

2014

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Autophagy as a potential therapeutic target in intervertebral disc degeneration

Life sciences (1973), 2021-05, Vol.273, p.119266-119266, Article 119266

2021

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Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity

Nature communications, 2021-05, Vol.12 (1), p.2621-2621, Article 2621

2021

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Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.462-481

2018

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Antimicrobial, Antioxidant, and Anti-Inflammatory Activities of Essential Oils from Five Selected Herbs

Bioscience, biotechnology, and biochemistry, 2011, Vol.75 (10), p.1977-1983

2011

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Recent Advances of SHP2 Inhibitors in Cancer Therapy: Current Development and Clinical Application

Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer

Exosomal microRNA‐16‐5p from human urine‐derived stem cells ameliorates diabetic nephropathy through protection of podocyte

Discovery of SHP2-D26 as a First, Potent, and Effective PROTAC Degrader of SHP2 Protein

Review of hair follicle dermal cells

Roles of NLRP3 inflammasome in intervertebral disc degeneration

CRISPR-Cas12-based detection of SARS-CoV-2

Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression

A Dual‐Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis

The assembly of succinate dehydrogenase: a key enzyme in bioenergetics

Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapy: Progress and Challenges

Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

Life Satisfaction and the Pursuit of Happiness on Twitter

Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands

Non-coding RNAs as regulators in epigenetics

Improving dengue fever predictions in Taiwan based on feature selection and random forests

Comparative Analyses of the Conformational Dynamics Between the Soluble and Membrane-Bound Cytokine Receptors

Inhibition of microRNA‐327 ameliorates ischemia/reperfusion injury‐induced cardiomyocytes apoptosis through targeting apoptosis repressor with caspase recruitment domain

Role of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective

Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California

Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death

Autophagy as a potential therapeutic target in intervertebral disc degeneration

Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Antimicrobial, Antioxidant, and Anti-Inflammatory Activities of Essential Oils from Five Selected Herbs

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