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A review of recent experiments on step-to-step “hand-off” of the DNA intermediates in mammalian base excision repair pathways

Molecular biology (New York), 2011-08, Vol.45 (4), p.586-550

2011

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DNA polymerases lose their grip

Nature structural & molecular biology, 2001-11, Vol.8 (11), p.915-917

2001

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Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

The Journal of biological chemistry, 1998-08, Vol.273 (33), p.21203-21209

1998

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DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change

The Journal of biological chemistry, 2001-02, Vol.276 (5), p.3408-3416

2001

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Subunits of human replication protein A are crosslinked by photoreactive primers synthesized by DNA polymerases

Nucleic acids research, 1998-01, Vol.26 (2), p.602-607

1998

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DNA polymerase beta and mammalian base excision repair

Cold Spring Harbor Symposia on Quantitative Biology, 2000, Vol.65, p.143

2000

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RNA polymerase II transcription. Rate of promoter clearance is enhanced by a purified activating transcription factor/cAMP response element-binding protein

The Journal of biological chemistry, 1994-04, Vol.269 (17), p.12755-12763

1994

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Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism

The Journal of biological chemistry, 1998-06, Vol.273 (24), p.15263-15270

1998

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The Fidelity of DNA Polymerase β during Distributive and Processive DNA Synthesis

The Journal of biological chemistry, 1999-02, Vol.274 (6), p.3642-3650

1999

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Unusual transient- and steady-state kinetic behavior is predicted by the kinetic scheme operational for recombinant human dihydrofolate reductase

The Journal of biological chemistry, 1990-02, Vol.265 (5), p.2740-2748

1990

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DNA Damage-Induced Transcriptional Activation of a Human DNA Polymerase .beta. Chimeric Promoter: Recruitment of Preinitiation Complex in Vitro by ATF/CREB

Biochemistry (Easton), 1995, Vol.34 (1), p.73-80

1995

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[11] Purification and domain-mapping of mammalian DNA polymerase β

Methods in Enzymology, 1995, Vol.262, p.98-107

1995

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Enzyme-DNA Interactions Required for Efficient Nucleotide Incorporation and Discrimination in Human DNA Polymerase β(∗)

The Journal of biological chemistry, 1996-05, Vol.271 (21), p.12141-12144

1996

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Substrate Binding by Human Apurinic/Apyrimidinic Endonuclease Indicates a Briggs-Haldane Mechanism

The Journal of biological chemistry, 1997-01, Vol.272 (2), p.1302-1307

1997

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Hydride transfer by dihydrofolate reductase. Causes and consequences of the wide range of rates exhibited by bacterial and vertebrate enzymes

The Journal of biological chemistry, 1989-06, Vol.264 (16), p.9391-9399

1989

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Structure and Mechanism of DNA Polymerase β

Chemical reviews, 2006-02, Vol.106 (2), p.361-382

2006

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DNA Lesion Bypass Polymerases Open Up

Structure, 2001-09, Vol.9 (9), p.759-764

2001

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Uniquely Altered DNA Replication Fidelity Conferred by an Amino Acid Change in the Nucleotide Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase

The Journal of biological chemistry, 1999-11, Vol.274 (46), p.32924-32930

1999

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Atypical transient state kinetics of recombinant human dihydrofolate reductase produced by hysteretic behavior. Comparison with dihydrofolate reductases from other sources

The Journal of biological chemistry, 1989-02, Vol.264 (5), p.2625-2633

1989

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Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove

The Journal of biological chemistry, 2000-05, Vol.275 (20), p.15025-15033

2000

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Role of the conserved active site residue tryptophan-24 of human dihydrofolate reductase as revealed by mutagenesis

Biochemistry (Easton), 1991-02, Vol.30 (5), p.1432-1440

1991

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Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions

The Journal of biological chemistry, 1998-11, Vol.273 (46), p.30435-30442

1998

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Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase

Biochemistry (Easton), 1990-07, Vol.29 (27), p.6428-6436

1990

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A minor groove binding track in reverse transcriptase

Nature structural biology, 1997-03, Vol.4 (3), p.194-197

1997

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The schizophrenia-like psychoses of epilepsy, V: Discussion and conclusions. 1963 [classical article]

The journal of neuropsychiatry and clinical neurosciences, 1995, Vol.7 (3), p.372-378

1995

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A review of recent experiments on step-to-step “hand-off” of the DNA intermediates in mammalian base excision repair pathways

DNA polymerases lose their grip

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change

Subunits of human replication protein A are crosslinked by photoreactive primers synthesized by DNA polymerases

DNA polymerase beta and mammalian base excision repair

RNA polymerase II transcription. Rate of promoter clearance is enhanced by a purified activating transcription factor/cAMP response element-binding protein

Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism

The Fidelity of DNA Polymerase β during Distributive and Processive DNA Synthesis

Unusual transient- and steady-state kinetic behavior is predicted by the kinetic scheme operational for recombinant human dihydrofolate reductase

DNA Damage-Induced Transcriptional Activation of a Human DNA Polymerase .beta. Chimeric Promoter: Recruitment of Preinitiation Complex in Vitro by ATF/CREB

[11] Purification and domain-mapping of mammalian DNA polymerase β

Enzyme-DNA Interactions Required for Efficient Nucleotide Incorporation and Discrimination in Human DNA Polymerase β(∗)

Substrate Binding by Human Apurinic/Apyrimidinic Endonuclease Indicates a Briggs-Haldane Mechanism

Hydride transfer by dihydrofolate reductase. Causes and consequences of the wide range of rates exhibited by bacterial and vertebrate enzymes

Structure and Mechanism of DNA Polymerase β

DNA Lesion Bypass Polymerases Open Up

Uniquely Altered DNA Replication Fidelity Conferred by an Amino Acid Change in the Nucleotide Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase

Atypical transient state kinetics of recombinant human dihydrofolate reductase produced by hysteretic behavior. Comparison with dihydrofolate reductases from other sources

Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove

Role of the conserved active site residue tryptophan-24 of human dihydrofolate reductase as revealed by mutagenesis

Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions

Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase

A minor groove binding track in reverse transcriptase

The schizophrenia-like psychoses of epilepsy, V: Discussion and conclusions. 1963 [classical article]

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