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Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

Cell stem cell, 2014-05, Vol.14 (5), p.673-688

2014

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Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

Cell reports (Cambridge), 2016-10, Vol.17 (5), p.1453-1461

2016

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DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

Nature genetics, 2016-09, Vol.48 (9), p.1014-1023

2016

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Environmental influences on clonal hematopoiesis

Experimental hematology, 2020-03, Vol.83, p.66-73

2020

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Less Is More: Unveiling the Functional Core of Hematopoietic Stem Cells through Knockout Mice

Cell stem cell, 2012-09, Vol.11 (3), p.302-317

2012

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Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo

Cell reports (Cambridge), 2018-04, Vol.23 (1), p.1-10

2018

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Acute loss of TET function results in aggressive myeloid cancer in mice

Nature communications, 2015-11, Vol.6 (1), p.10071-10071, Article 10071

2015

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PPM1D in Solid and Hematologic Malignancies: Friend and Foe?

Molecular cancer research, 2022-09, Vol.20 (9), p.1365-1378

2022

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DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia

Blood, 2016-08, Vol.128 (7), p.971-981

2016

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New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells

Experimental hematology, 2014-08, Vol.42 (8), p.609-617

2014

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A gallon of sweat to make a pint of blood

The Journal of experimental medicine, 2014-06, Vol.211 (7), p.1271-1272

Goodell, Margaret A

2014

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Molecular signatures of proliferation and quiescence in hematopoietic stem cells

PLoS biology, 2004-10, Vol.2 (10), p.e301-e301

2004

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Single-cell technology meets hematology: introduction to a review series

Blood, 2019-03, Vol.133 (13), p.1387-1388

2019

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Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells

Experimental hematology, 2010-05, Vol.38 (5), p.403-416

2010

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Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells

PloS one, 2011-10, Vol.6 (10), p.e26410-e26410

2011

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Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

Journal of visualized experiments, 2018-04 (134)

2018

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CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway

PLoS biology, 2011-09, Vol.9 (9), p.e1001148-e1001148

2011

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DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells

Nature cell biology, 2023-04, Vol.25 (4), p.528-539

2023

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Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing

Nature cell biology, 2024-04, Vol.26 (4), p.593-603

2024

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Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells

PloS one, 2008-06, Vol.3 (6), p.e2357-e2357

2008

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Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling

Blood, 2011-08, Vol.118 (6), p.1525-1533

2011

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Comparative long-term effects of interferon α and hydroxyurea on human hematopoietic progenitor cells

Experimental hematology, 2015-10, Vol.43 (10), p.912-918.e2

2015

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Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity

PLoS biology, 2008-04, Vol.6 (4), p.e93-e93

2008

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TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells

Nature aging, 2023-11, Vol.3 (11), p.1387-1400

2023

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Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery

PLoS genetics, 2013-03, Vol.9 (3), p.e1003359-e1003359

2013

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Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

Environmental influences on clonal hematopoiesis

Less Is More: Unveiling the Functional Core of Hematopoietic Stem Cells through Knockout Mice

Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo

Acute loss of TET function results in aggressive myeloid cancer in mice

PPM1D in Solid and Hematologic Malignancies: Friend and Foe?

DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia

New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells

A gallon of sweat to make a pint of blood

Molecular signatures of proliferation and quiescence in hematopoietic stem cells

Single-cell technology meets hematology: introduction to a review series

Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells

Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells

Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway

DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells

Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing

Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells

Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling

Comparative long-term effects of interferon α and hydroxyurea on human hematopoietic progenitor cells

Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity

TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells

Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery

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