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Clonal hematopoiesis: mechanisms driving dominance of stem cell clones

Blood, 2020-10, Vol.136 (14), p.1590-1598

2020

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DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

Nature genetics, 2016-09, Vol.48 (9), p.1014-1023

2016

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Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing

Blood, 2012-03, Vol.119 (11), p.2500-2509

2012

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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

PLoS biology, 2007-08, Vol.5 (8), p.e201-e201

2007

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Environmental influences on clonal hematopoiesis

Experimental hematology, 2020-03, Vol.83, p.66-73

2020

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Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation

Blood, 2015-01, Vol.125 (4), p.629-638

2015

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A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells

Blood, 2013-12, Vol.122 (25), p.4086-4089

2013

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New insights into the biology of acute myeloid leukemia with mutated NPM1

International journal of hematology, 2019-08, Vol.110 (2), p.150-160

2019

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DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia

Blood, 2016-08, Vol.128 (7), p.971-981

2016

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New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells

Experimental hematology, 2014-08, Vol.42 (8), p.609-617

2014

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Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis

Blood, 2020-03, Vol.135 (11), p.845-856

2020

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Single-cell technology meets hematology: introduction to a review series

Blood, 2019-03, Vol.133 (13), p.1387-1388

2019

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Mixed Phenotype Acute Leukemia (MPAL) Exhibits Frequent Mutations in DNMT3A and Activated Signaling Genes

Experimental hematology, 2016-08, Vol.44 (8), p.740-744

2016

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Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells

Experimental hematology, 2010-05, Vol.38 (5), p.403-416

2010

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Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies

Cancer letters, 2019-12, Vol.467, p.1-8

2019

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Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome

Haematologica (Roma), 2022-04, Vol.107 (4), p.887-898

2022

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The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging

Blood, 2007-02, Vol.109 (4), p.1736-1742

2007

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Dose-dependent effects of Dnmt3a in an inducible murine model of KrasG12D-driven leukemia

Experimental hematology, 2024-07, Vol.135, p.104248, Article 104248

2024

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Epigenetics in hematology: introducing a collection of reviews

Blood, 2013-04, Vol.121 (16), p.3059-3060

2013

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Mutant NPM1 marginally impacts ribosome footprint in acute myeloid leukemia cells

EJHaem, 2024-10, Vol.5 (5), p.1028-1032

2024

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CD150− side population cells represent a functionally distinct population of long-term hematopoietic stem cells

Blood, 2008-02, Vol.111 (4), p.2444-2451

2008

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Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice

Leukemia, 2021-07, Vol.35 (7), p.1949-1963

2021

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Incipient clonal hematopoiesis is accelerated following CD30.CAR-T therapy

Cytotherapy (Oxford, England), 2024-03, Vol.26 (3), p.261-265

2024

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Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells

PloS one, 2008-06, Vol.3 (6), p.e2357-e2357

2008

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Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling

Blood, 2011-08, Vol.118 (6), p.1525-1533

2011

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Clonal hematopoiesis: mechanisms driving dominance of stem cell clones

DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

Environmental influences on clonal hematopoiesis

Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation

A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells

New insights into the biology of acute myeloid leukemia with mutated NPM1

DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia

New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells

Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis

Single-cell technology meets hematology: introduction to a review series

Mixed Phenotype Acute Leukemia (MPAL) Exhibits Frequent Mutations in DNMT3A and Activated Signaling Genes

Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells

Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies

Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome

The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging

Dose-dependent effects of Dnmt3a in an inducible murine model of KrasG12D-driven leukemia

Epigenetics in hematology: introducing a collection of reviews

Mutant NPM1 marginally impacts ribosome footprint in acute myeloid leukemia cells

CD150− side population cells represent a functionally distinct population of long-term hematopoietic stem cells

Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice

Incipient clonal hematopoiesis is accelerated following CD30.CAR-T therapy

Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells

Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling

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