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Nutritional Signaling via Free Fatty Acid Receptors

International Journal of Molecular Sciences, 2016-03, Vol.17 (4), p.450-450

2016

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Free fatty acid receptors as therapeutic targets for the treatment of diabetes

Frontiers in pharmacology, 2014-11, Vol.5, p.236-236

2014

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Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

Frontiers in pharmacology, 2023-07, Vol.14, p.1197743-1197743

2023

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Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

Peptides (New York, N.Y. : 1980), 2020-12, Vol.134, p.170419-170419, Article 170419

2020

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Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

Journal of neuroinflammation, 2017-04, Vol.14 (1), p.91-91, Article 91

2017

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Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells

Biochemical pharmacology, 2022-12, Vol.206, p.115328, Article 115328

2022

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Novel advances in understanding fatty acid–binding G protein–coupled receptors and their roles in controlling energy balance

Nutrition reviews, 2022-01, Vol.80 (2), p.187-199

2022

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Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development

Expert opinion on investigational drugs, 2016-08, Vol.25 (8), p.871-890

2016

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Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells

Diabetologia, 2013-06, Vol.56 (6), p.1413-1416

2013

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Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics

Current medicinal chemistry, 2013-10, Vol.20 (31), p.3855-3871

2013

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Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action

ACS medicinal chemistry letters, 2022-12, Vol.13 (12), p.1839-1847

2022

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Dietary Fatty Acids and Their Potential for Controlling Metabolic Diseases Through Activation of FFA4 GPR120

Annual review of nutrition, 2015-07, Vol.35 (1), p.239-263

2015

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The regulation of adipogenesis through GPR120

Biochemical and biophysical research communications, 2007-03, Vol.354 (2), p.591-597

2007

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A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice

Biomedicine & pharmacotherapy, 2021-07, Vol.139, p.111613-111613, Article 111613

2021

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Different effects of G-protein-coupled receptor 120 (GPR120) and GPR40 on cell motile activity of highly migratory osteosarcoma cells

Biochemical and biophysical research communications, 2017-03, Vol.484 (3), p.675-680

2017

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Involvement of G-Protein-Coupled Receptor 40 in the Inhibitory Effects of Docosahexaenoic Acid on SREBP1-Mediated Lipogenic Enzyme Expression in Primary Hepatocytes

International journal of molecular sciences, 2019-05, Vol.20 (11), p.2625

2019

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Isoprenoid Derivatives of Lysophosphatidylcholines Enhance Insulin and GLP-1 Secretion through Lipid-Binding GPCRs

International journal of molecular sciences, 2021-05, Vol.22 (11), p.5748

2021

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Different roles of GPR120 and GPR40 in the acquisition of malignant properties in pancreatic cancer cells

Biochemical and biophysical research communications, 2015-09, Vol.465 (3), p.512-515

2015

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Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

British journal of pharmacology, 2006-07, Vol.148 (5), p.619-628

2006

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Targeting FFA1 and FFA4 receptors in cancer-induced cachexia

American journal of physiology: endocrinology and metabolism, 2020-11, Vol.319 (5), p.E877-E892

2020

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Free fatty acids induce cholecystokinin secretion through GPR120

Naunyn-Schmiedeberg's archives of pharmacology, 2008-06, Vol.377 (4-6), p.523-527

2008

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Different effects of GPR120 and GPR40 on cellular functions stimulated by 12-O-tetradecanoylphorbol-13-acetate in melanoma cells

Biochemical and biophysical research communications, 2016-06, Vol.475 (1), p.25-30

2016

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Diverse effects of G-protein-coupled free fatty acid receptors on the regulation of cellular functions in lung cancer cells

Experimental cell research, 2016-03, Vol.342 (2), p.193-199

2016

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Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes

Bioorganic & medicinal chemistry letters, 2018-03, Vol.28 (5), p.841-846

2018

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Characterization of duodenal expression and localization of fatty acid-sensing receptors in humans: relationships with body mass index

American journal of physiology: Gastrointestinal and liver physiology, 2014-11, Vol.307 (10), p.G958-G967

2014

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Nutritional Signaling via Free Fatty Acid Receptors

Free fatty acid receptors as therapeutic targets for the treatment of diabetes

Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells

Novel advances in understanding fatty acid–binding G protein–coupled receptors and their roles in controlling energy balance

Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development

Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells

Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics

Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action

Dietary Fatty Acids and Their Potential for Controlling Metabolic Diseases Through Activation of FFA4 GPR120

The regulation of adipogenesis through GPR120

A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice

Different effects of G-protein-coupled receptor 120 (GPR120) and GPR40 on cell motile activity of highly migratory osteosarcoma cells

Involvement of G-Protein-Coupled Receptor 40 in the Inhibitory Effects of Docosahexaenoic Acid on SREBP1-Mediated Lipogenic Enzyme Expression in Primary Hepatocytes

Isoprenoid Derivatives of Lysophosphatidylcholines Enhance Insulin and GLP-1 Secretion through Lipid-Binding GPCRs

Different roles of GPR120 and GPR40 in the acquisition of malignant properties in pancreatic cancer cells

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

Targeting FFA1 and FFA4 receptors in cancer-induced cachexia

Free fatty acids induce cholecystokinin secretion through GPR120

Different effects of GPR120 and GPR40 on cellular functions stimulated by 12-O-tetradecanoylphorbol-13-acetate in melanoma cells

Diverse effects of G-protein-coupled free fatty acid receptors on the regulation of cellular functions in lung cancer cells

Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes

Characterization of duodenal expression and localization of fatty acid-sensing receptors in humans: relationships with body mass index

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