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The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation

Nature reviews. Genetics, 2010-11, Vol.11 (11), p.761-772

2010

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H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation

Cell, 2013-02, Vol.152 (5), p.1021-1036

2013

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SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53

Cell, 2013-07, Vol.154 (2), p.297-310

2013

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RNA polymerase II–associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II

Science (American Association for the Advancement of Science), 2015-12, Vol.350 (6266), p.1383-1386

2015

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RNF20 Inhibits TFIIS-Facilitated Transcriptional Elongation to Suppress Pro-oncogenic Gene Expression

Molecular cell, 2011-05, Vol.42 (4), p.477-488

2011

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Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors

Molecular cell, 2012-02, Vol.45 (3), p.330-343

2012

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Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

Cell, 2011-02, Vol.144 (4), p.513-525

2011

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Direct Interactions of OCA-B and TFII-I Regulate Immunoglobulin Heavy-Chain Gene Transcription by Facilitating Enhancer-Promoter Communication

Molecular cell, 2011-05, Vol.42 (3), p.342-355

2011

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

Nature structural & molecular biology, 2006-08, Vol.13 (8), p.713-719

2006

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Inhibition of Adhesion Molecule Gene Expression and Cell Adhesion by the Metabolic Regulator PGC-1α

PloS one, 2016-12, Vol.11 (12), p.e0165598-e0165598

2016

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Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.3901-3906

2013

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The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

Science (American Association for the Advancement of Science), 2011-08, Vol.333 (6043), p.765-769

2011

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Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (38), p.15751-15756

2011

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tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (21), p.8513-8518

2009

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Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer

PloS one, 2020-03, Vol.15 (3), p.e0230670-e0230670

2020

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muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (22), p.10196-10201

2010

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Enhancer–promoter communication and transcriptional regulation of Igh

Trends in immunology, 2011-11, Vol.32 (11), p.532-539

2011

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Menin and MLL Cooperatively Regulate Expression of Cyclin-Dependent Kinase Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2005-01, Vol.102 (3), p.749-754

2005

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Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (15), p.6765-6770

2010

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MLL Associates Specifically with a Subset of Transcriptionally Active Target Genes

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (41), p.14765-14770

2005

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Polyglutamine-Expanded Ataxin-7 Inhibits STAGA Histone Acetyltransferase Activity to Produce Retinal Degeneration

Proceedings of the National Academy of Sciences - PNAS, 2005-06, Vol.102 (24), p.8472-8477

2005

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Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (52), p.21319-21324

2012

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Coactivator as a Target Gene Specificity Determinant for Histone H3 Lysine 4 Methyltransferases

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (42), p.15392-15397

2006

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Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4176-4181

2010

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Coactivator condensation at super-enhancers links phase separation and gene control

Science (American Association for the Advancement of Science), 2018-07, Vol.361 (6400)

2018

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The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation

H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation

SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53

RNA polymerase II–associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II

RNF20 Inhibits TFIIS-Facilitated Transcriptional Elongation to Suppress Pro-oncogenic Gene Expression

Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

Direct Interactions of OCA-B and TFII-I Regulate Immunoglobulin Heavy-Chain Gene Transcription by Facilitating Enhancer-Promoter Communication

Regulation of MLL1 H3K4 methyltransferase activity by its core components

Inhibition of Adhesion Molecule Gene Expression and Cell Adhesion by the Metabolic Regulator PGC-1α

Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia

The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes

tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4

Efficacy of a small molecule inhibitor of the transcriptional cofactor PC4 in prevention and treatment of non-small cell lung cancer

muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism

Enhancer–promoter communication and transcriptional regulation of Igh

Menin and MLL Cooperatively Regulate Expression of Cyclin-Dependent Kinase Inhibitors

Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation

MLL Associates Specifically with a Subset of Transcriptionally Active Target Genes

Polyglutamine-Expanded Ataxin-7 Inhibits STAGA Histone Acetyltransferase Activity to Produce Retinal Degeneration

Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes

Coactivator as a Target Gene Specificity Determinant for Histone H3 Lysine 4 Methyltransferases

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation

Coactivator condensation at super-enhancers links phase separation and gene control

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