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Role of modelling and simulation in Phase I drug development

European journal of pharmaceutical sciences, 2001-05, Vol.13 (2), p.115-122

2001

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Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey

British journal of clinical pharmacology, 2007-11, Vol.64 (5), p.603-612

2007

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Modeling the Kinetics of Release of Octreotide from Long‐Acting Formulations Injected Intramuscularly in Rabbits

Journal of pharmaceutical sciences, 2000-09, Vol.89 (9), p.1123-1133

2000

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Robust optimal design for the estimation of hyperparameters in population pharmacokinetics

Journal of pharmacokinetics and biopharmaceutics, 1998-12, Vol.26 (6), p.689-716

1998

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Optimization of individual and population designs using Splus

Journal of pharmacokinetics and pharmacodynamics, 2003-12, Vol.30 (6), p.417-443

2003

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Modeling INR data to predict maintenance fluindione dosage

Therapeutic drug monitoring, 1998-12, Vol.20 (6), p.631-639

1998

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Population kinetics and conditional assessment of the optimal dosage regimen using the P-PHARM software package

Anticancer research, 1994-11, Vol.14 (6A), p.2321

1994

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Sparse-Sampling Optimal Designs in Pharmacokinetics and Toxicokinetics

Therapeutic innovation & regulatory science, 1995, Vol.29 (3), p.997-1019

1995

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Rapid and simple micromethod for the quantification of fluindione in human plasma using high-performance liquid chromatography

Journal of chromatography. B, Biomedical sciences and applications, 1998-04, Vol.707 (1), p.169-173

1998

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The use of population pharmacokinetics in drug development

Clinical pharmacokinetics, 1996-02, Vol.30 (2), p.81-93

1996

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Bayesian design criteria : computation, comparison, and application to a pharmacokinetic and a pharmacodynamic model

Journal of pharmacokinetics and biopharmaceutics, 1995-02, Vol.23 (1), p.101-125

1995

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New strategies in drug development and clinical evaluation : the population approach : commentary on an action for co-operative research

European journal of clinical pharmacology, 1993-09, Vol.45 (2), p.93-94

1993

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Nonparametric maximum likelihood estimation for population pharmacokinetics, with application to cyclosporine

Journal of pharmacokinetics and biopharmaceutics, 1988-06, Vol.16 (3), p.311-327

1988

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Role of modelling and simulation in Phase I drug development

Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey

Modeling the Kinetics of Release of Octreotide from Long‐Acting Formulations Injected Intramuscularly in Rabbits

Robust optimal design for the estimation of hyperparameters in population pharmacokinetics

Optimization of individual and population designs using Splus

Modeling INR data to predict maintenance fluindione dosage

Population kinetics and conditional assessment of the optimal dosage regimen using the P-PHARM software package

Sparse-Sampling Optimal Designs in Pharmacokinetics and Toxicokinetics

Rapid and simple micromethod for the quantification of fluindione in human plasma using high-performance liquid chromatography

The use of population pharmacokinetics in drug development

Bayesian design criteria : computation, comparison, and application to a pharmacokinetic and a pharmacodynamic model

New strategies in drug development and clinical evaluation : the population approach : commentary on an action for co-operative research

Nonparametric maximum likelihood estimation for population pharmacokinetics, with application to cyclosporine

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