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Glutathione-associated enzymes in anticancer drug resistance

Cancer research (Chicago, Ill.), 1994-08, Vol.54 (16), p.4313-4320

TEW, K. D

1994

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Combined antimicrotubule activity of estramustine and taxol in human prostatic carcinoma cell lines

Cancer research (Chicago, Ill.), 1992-08, Vol.52 (16), p.4433-4440

1992

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Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines

Cancer chemotherapy and pharmacology, 1996, Vol.37 (4), p.363-370

1996

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P-glycoprotein Binding and Modulation of the Multidrug-Resistant Phenotype by Estramustine

JNCI : Journal of the National Cancer Institute, 1994-05, Vol.86 (9), p.688-694

1994

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Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid

Biochemical pharmacology, 1991-09, Vol.42 (7), p.1504-1507

1991

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Glutathione and Drug Resistance

Cancer investigation, 1996, Vol.14 (2), p.158-168

1996

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Overproduction of a 37.5-kDa cytosolic protein structurally related to prostaglandin F synthase in ethacrynic acid-resistant human colon cells

Molecular pharmacology, 1993-06, Vol.43 (6), p.845-853

1993

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The effects of estramustine on metaphase and anaphase in DU 145 prostatic carcinoma cells

European journal of cell biology, 1991-04, Vol.54 (2), p.268-276

1991

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Estramustine—A nitrogen mustard/steroid with antimicrotubule activity

Pharmacology & therapeutics (Oxford), 1989, Vol.43 (3), p.299-319

1989

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Modulation of P‐glycoprotein activity by estramustine is limited by binding to plasma proteins

Cancer, 1995-05, Vol.75 (10), p.2597-2604

1995

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Resistance to the antimitotic drug estramustine is distinct from the multidrug resistant phenotype

British journal of cancer, 1991-08, Vol.64 (2), p.267-273

1991

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Molecular conformation of estramustine and two analogues

Molecular pharmacology, 1992-03, Vol.41 (3), p.569-576

1992

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Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards

Biochemical pharmacology, 1989-06, Vol.38 (12), p.1915-1921

1989

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Carbamoylation of glutathione reductase and changes in cellular and chromosome morphology in a rat cell line resistant to nitrogen mustards but collaterally sensitive to nitrosoureas

Cancer research (Chicago, Ill.), 1985-05, Vol.45 (5), p.2326-2333

1985

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Selection of nitrogen mustard resistance in a rat tumor cell line results in loss of guanine-O6-alkyl transferase activity

Molecular pharmacology, 1986-07, Vol.30 (1), p.77-80

1986

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PABA/NO as an Anticancer Lead: Analogue Synthesis, Structure Revision, Solution Chemistry, Reactivity toward Glutathione, and in Vitro Activity

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.1157-1164

2006

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Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards

Cancer treatment reports, 1985-06, Vol.69 (6), p.677

1985

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A comparative analysis of drug-induced DNA effects in a nitrogen mustard resistant cell line expressing sensitivity to nitrosoureas

Biochemical pharmacology, 1986-04, Vol.35 (7), p.1171-1176

1986

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DNA repeat length in chromatin from murine bone marrow and L1210 leukaemia cells

British journal of cancer, 1985-09, Vol.52 (3), p.377-382

1985

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Poly(adenosine diphosphate-ribosylation) of nuclear matrix proteins in alkylating agent resistant and sensitive cell lines

Chemico-biological interactions, 1985-01, Vol.54 (2), p.209-222

1985

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Alkylating agent interactions with the nuclear matrix

Biochemical pharmacology, 1983-12, Vol.32 (23), p.3509-3516

1983

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Increase of βIII- and βIVa-tubulin isotypes in human prostate carcinoma cells as a result of estramustine resistance

Cancer research (Chicago, Ill.), 1996-06, Vol.56 (11), p.2584-2589

1996

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Influence of glutathione S‐transferase pi and p53 expression on tumor frequency and spectrum in mice

International journal of cancer, 2005-01, Vol.113 (1), p.29-35

2005

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Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid: Pathways of aqueous decomposition and pharmacological characteristics of new anticancer disulfide-linked nitrosoureas

Biochemical pharmacology, 1985-01, Vol.34 (7), p.1015-1024

1985

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Relationship of glutathione depletion and inhibition of glutathione-S-transferase activity to the antimitotic properties of estramustine

Cancer treatment reports, 1986-06, Vol.70 (6), p.715

1986

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Glutathione-associated enzymes in anticancer drug resistance

Combined antimicrotubule activity of estramustine and taxol in human prostatic carcinoma cell lines

Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines

P-glycoprotein Binding and Modulation of the Multidrug-Resistant Phenotype by Estramustine

Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid

Glutathione and Drug Resistance

Overproduction of a 37.5-kDa cytosolic protein structurally related to prostaglandin F synthase in ethacrynic acid-resistant human colon cells

The effects of estramustine on metaphase and anaphase in DU 145 prostatic carcinoma cells

Estramustine—A nitrogen mustard/steroid with antimicrotubule activity

Modulation of P‐glycoprotein activity by estramustine is limited by binding to plasma proteins

Resistance to the antimitotic drug estramustine is distinct from the multidrug resistant phenotype

Molecular conformation of estramustine and two analogues

Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards

Carbamoylation of glutathione reductase and changes in cellular and chromosome morphology in a rat cell line resistant to nitrogen mustards but collaterally sensitive to nitrosoureas

Selection of nitrogen mustard resistance in a rat tumor cell line results in loss of guanine-O6-alkyl transferase activity

PABA/NO as an Anticancer Lead: Analogue Synthesis, Structure Revision, Solution Chemistry, Reactivity toward Glutathione, and in Vitro Activity

Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards

A comparative analysis of drug-induced DNA effects in a nitrogen mustard resistant cell line expressing sensitivity to nitrosoureas

DNA repeat length in chromatin from murine bone marrow and L1210 leukaemia cells

Poly(adenosine diphosphate-ribosylation) of nuclear matrix proteins in alkylating agent resistant and sensitive cell lines

Alkylating agent interactions with the nuclear matrix

Increase of βIII- and βIVa-tubulin isotypes in human prostate carcinoma cells as a result of estramustine resistance

Influence of glutathione S‐transferase pi and p53 expression on tumor frequency and spectrum in mice

Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid: Pathways of aqueous decomposition and pharmacological characteristics of new anticancer disulfide-linked nitrosoureas

Relationship of glutathione depletion and inhibition of glutathione-S-transferase activity to the antimitotic properties of estramustine

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