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Analytical strategy for the detection of ecdysterone and its metabolites in vivo in uPA(+/+)‐SCID mice with humanized liver, human urine samples, and estimation of prevalence of its use in anti‐doping samples

Drug testing and analysis, 2021-07, Vol.13 (7), p.1341-1353

2021

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Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells

Matrix biology, 2015-04, Vol.43, p.42-60

2015

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Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (20), p.3372-3375

2018

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Role of poFUT1 and O-fucosylation in placental angiogenesis

Biology of reproduction, 2023-04, Vol.108 (4), p.553-563

2023

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Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients

European journal of cancer (1990), 2013-05, Vol.49 (8), p.1825-1835

2013

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Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer

Biochimica et biophysica acta, 2013-12, Vol.1833 (12), p.2961-2969

2013

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uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R

BMC cancer, 2016-08, Vol.16 (1), p.615, Article 615

2016

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The urokinase plasminogen activator system in breast cancer invasion and metastasis

Biomedicine & pharmacotherapy, 2013-03, Vol.67 (2), p.179-182

2013

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A prospective, randomized, pharmacodynamic study of quick-starting a desogestrel progestin-only pill following ulipristal acetate for emergency contraception

Human reproduction (Oxford), 2015-12, Vol.30 (12), p.2785-2793

2015

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uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells

International journal of cancer, 2017-09, Vol.141 (6), p.1190-1200

2017

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Systematic evaluation of structure–property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride

Bioorganic & medicinal chemistry, 2021-05, Vol.37, p.116116, Article 116116

2021

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Molecular and protein markers for clinical decision making in breast cancer: Today and tomorrow

Cancer treatment reviews, 2014-04, Vol.40 (3), p.434-444

2014

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CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer

Oncogene, 2013-05, Vol.32 (18), p.2282-2291

2013

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Ulipristal acetate and liver-injuries: while Esmya is revoked, EllaOne is allowed in repeated self-administrations possibly exceeding UPA toxic-dosing with Esmya

Journal of hepatology, 2021-03, Vol.74 (3), p.750-751

Mozzanega, Bruno

2021

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The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion

Oncogene, 2012-09, Vol.31 (39), p.4279-4289

2012

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Phase II randomised proof-of-concept study of the urokinase inhibitor upamostat (WX-671) in combination with gemcitabine compared with gemcitabine alone in patients with non-resectable, locally advanced pancreatic cancer

British journal of cancer, 2013-03, Vol.108 (4), p.766-770

2013

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Prognostic impact of urokinase-type plasminogen activator system components in clear cell renal cell carcinoma patients without distant metastasis

BMC cancer, 2014-12, Vol.14 (1), p.974-974, Article 974

2014

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Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2999

2021

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Elevated levels of serum urokinase plasminogen activator predict poor prognosis in hepatocellular carcinoma after resection

BMC cancer, 2019-12, Vol.19 (1), p.1169-1169, Article 1169

2019

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Morphological and microarray analyses of human hepatocytes from xenogeneic host livers

Laboratory investigation, 2013-01, Vol.93 (1), p.54-71

2013

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Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: new insights from protein microarray analysis

The Journal of pathology, 2011, Vol.223 (1), p.54-63

2011

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Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer

Oncogene, 2009-11, Vol.28 (44), p.3937-3948

2009

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Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53 microRNA-23b urokinase-type plasminogen activator pathway

Oncogene, 2011-05, Vol.30 (21), p.2401-2410

2011

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Small-size circulating microparticles in acute coronary syndromes: Relevance to fibrinolytic status, reparative markers and outcomes

Atherosclerosis, 2013-04, Vol.227 (2), p.313-322

2013

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uPA affects the CRSsNP nasal mucosa epithelium apoptosis by regulating WIF1

Experimental cell research, 2019-04, Vol.377 (1-2), p.75-85

2019

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Analytical strategy for the detection of ecdysterone and its metabolites in vivo in uPA(+/+)‐SCID mice with humanized liver, human urine samples, and estimation of prevalence of its use in anti‐doping samples

Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells

Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis

Role of poFUT1 and O-fucosylation in placental angiogenesis

Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients

Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer

uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R

The urokinase plasminogen activator system in breast cancer invasion and metastasis

A prospective, randomized, pharmacodynamic study of quick-starting a desogestrel progestin-only pill following ulipristal acetate for emergency contraception

uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells

Systematic evaluation of structure–property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride

Molecular and protein markers for clinical decision making in breast cancer: Today and tomorrow

CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer

Ulipristal acetate and liver-injuries: while Esmya is revoked, EllaOne is allowed in repeated self-administrations possibly exceeding UPA toxic-dosing with Esmya

The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion

Phase II randomised proof-of-concept study of the urokinase inhibitor upamostat (WX-671) in combination with gemcitabine compared with gemcitabine alone in patients with non-resectable, locally advanced pancreatic cancer

Prognostic impact of urokinase-type plasminogen activator system components in clear cell renal cell carcinoma patients without distant metastasis

Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors

Elevated levels of serum urokinase plasminogen activator predict poor prognosis in hepatocellular carcinoma after resection

Morphological and microarray analyses of human hepatocytes from xenogeneic host livers

Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: new insights from protein microarray analysis

Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer

Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53 microRNA-23b urokinase-type plasminogen activator pathway

Small-size circulating microparticles in acute coronary syndromes: Relevance to fibrinolytic status, reparative markers and outcomes

uPA affects the CRSsNP nasal mucosa epithelium apoptosis by regulating WIF1

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