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Targeting a neoantigen derived from a common TP53 mutation

Science (American Association for the Advancement of Science), 2021-03, Vol.371 (6533)

2021

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Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode

Nature (London), 2016-10, Vol.538 (7623), p.118-122

2016

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Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity

Cell death and differentiation, 2017-02, Vol.24 (2), p.357-370

2017

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In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

Journal of the American Chemical Society, 2013-08, Vol.135 (31), p.11623-11633

2013

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p53 pathway dysfunction is highly prevalent in acute myeloid leukemia independent of TP53 mutational status

Leukemia, 2017-06, Vol.31 (6), p.1296-1305

2017

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Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells

The Journal of biological chemistry, 2019-06, Vol.294 (24), p.9430-9439

2019

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Higher Order Protein Catenation Leads to an Artificial Antibody with Enhanced Affinity and In Vivo Stability

Journal of the American Chemical Society, 2021-11, Vol.143 (43), p.18029-18040

2021

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MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8), p.2587-2597

2013

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TP53 Mutation and Its Prognostic Significance in Waldenstrom's Macroglobulinemia

Clinical cancer research, 2017-10, Vol.23 (20), p.6325-6335

2017

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Sulfated glycosaminoglycans mediate prion-like behavior of p53 aggregates

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (52), p.33225-33234

2020

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Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins

Science signaling, 2017-09, Vol.10 (495)

2017

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Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors

The international journal of biochemistry & cell biology, 2011, Vol.43 (1), p.60-64

2011

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Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification

Nature methods, 2014, Vol.11 (1), p.73-78

2014

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Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs

Cell cycle (Georgetown, Tex.), 2011-05, Vol.10 (10), p.1679-1689

2011

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Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53

Cancer research (Chicago, Ill.), 2017-09, Vol.77 (18), p.4961-4972

2017

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Bioinformatics and experimental findings reveal the therapeutic actions and targets of pachymic acid against cystitis glandularis

BioFactors (Oxford), 2021-07, Vol.47 (4), p.665-673

2021

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A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease

Human molecular genetics, 2015-04, Vol.24 (7), p.1929-1944

2015

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Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells

BMC cancer, 2020-06, Vol.20 (1), p.583-583, Article 583

2020

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The tumor suppressor PTEN interacts with p53 in hereditary cancer

International journal of oncology, 2014-06, Vol.44 (6), p.1813-1819

2014

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Plk1 phosphorylation of Numb leads to impaired DNA damage response

Oncogene, 2018-02, Vol.37 (6), p.810-820

2018

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Evaluation of the Role of p53 Tumour Suppressor Posttranslational Modifications and TTC5 Cofactor in Lung Cancer

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13198

2021

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Development of a T-cell Receptor Mimic Antibody against Wild-Type p53 for Cancer Immunotherapy

Cancer research (Chicago, Ill.), 2017-05, Vol.77 (10), p.2699-2711

2017

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Alternative splicings on p53, BRCA1 and PTEN genes involved in breast cancer

Biochemical and biophysical research communications, 2011-09, Vol.413 (3), p.395-399

2011

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Signals from the Metastatic Niche Regulate Early and Advanced Ovarian Cancer Metastasis through miR-4454 Downregulation

Molecular cancer research, 2020-08, Vol.18 (8), p.1202-1217

2020

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Targeting a neoantigen derived from a common TP53 mutation

Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode

Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity

Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

p53 pathway dysfunction is highly prevalent in acute myeloid leukemia independent of TP53 mutational status

Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells

Higher Order Protein Catenation Leads to an Artificial Antibody with Enhanced Affinity and In Vivo Stability

MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models

TP53 Mutation and Its Prognostic Significance in Waldenstrom's Macroglobulinemia

Sulfated glycosaminoglycans mediate prion-like behavior of p53 aggregates

Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins

Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors

Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification

Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs

Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53

Bioinformatics and experimental findings reveal the therapeutic actions and targets of pachymic acid against cystitis glandularis

A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease

Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells

The tumor suppressor PTEN interacts with p53 in hereditary cancer

Plk1 phosphorylation of Numb leads to impaired DNA damage response

Evaluation of the Role of p53 Tumour Suppressor Posttranslational Modifications and TTC5 Cofactor in Lung Cancer

Development of a T-cell Receptor Mimic Antibody against Wild-Type p53 for Cancer Immunotherapy

Alternative splicings on p53, BRCA1 and PTEN genes involved in breast cancer

Signals from the Metastatic Niche Regulate Early and Advanced Ovarian Cancer Metastasis through miR-4454 Downregulation

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