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In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

British journal of cancer, 2002-05, Vol.86 (10), p.1652-1657

2002

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A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer

Annals of oncology, 2008-07, Vol.19 (7), p.1340-1346

2008

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Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo

British journal of cancer, 2014-07, Vol.111 (2), p.318-325

2014

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Phase II studies of BBR3464, a novel tri-nuclear platinum complex, in patients with gastric or gastro-oesophageal adenocarcinoma

European journal of cancer (1990), 2004-08, Vol.40 (12), p.1872-1877

2004

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Scheduling nab-paclitaxel combined with gemcitabine as first-line treatment for metastatic pancreatic adenocarcinoma

British journal of cancer, 2020-06, Vol.122 (12), p.1760-1768

2020

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Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma

British journal of cancer, 2001-12, Vol.85 (12), p.1937-1943

2001

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Relationships between carboplatin exposure and tumor response and toxicity in patients with ovarian cancer

Journal of clinical oncology, 1992-04, Vol.10 (4), p.520-528

1992

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Evaluation of rodent-only toxicology for early clinical trials with novel cancer therapeutics

British Journal of Cancer, 1999-11, Vol.81 (5), p.760-768

1999

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5-fluorouracil steady state pharmacokinetics and outcome in patients receiving protracted venous infusion for advanced colorectal cancer

British journal of cancer, 2001-03, Vol.84 (5), p.600-603

2001

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A phase I and pharmacological study of the matrix metalloproteinase inhibitor BB-3644 in patients with solid tumours

British journal of cancer, 2004-02, Vol.90 (4), p.800-804

2004

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Population pharmacokinetics of gentamicin in patients with cancer

British journal of clinical pharmacology, 1998-09, Vol.46 (3), p.229-236

1998

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Platinum distribution in malignant glioma following intraoperative intravenous infusion of carboplatin

British journal of neurosurgery, 1999-04, Vol.13 (2), p.132-137

1999

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Identification of a region of frequent loss of heterozygosity at 11q24 in colorectal cancer

Cancer research (Chicago, Ill.), 1999-06, Vol.59 (12), p.2806-2809

1999

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Dose-limiting neurotoxicity in a phase I study of penclomedine (NSC 388720, CRC 88-04), a synthetic α-picoline derivative, administered intravenously

British journal of cancer, 1998-03, Vol.77 (5), p.808-811

1998

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Impact of cyclophosphamide on relationships between carboplatin exposure and response or toxicity when used in the treatment of advanced ovarian cancer

Journal of clinical oncology, 1993-06, Vol.11 (6), p.1156-1164

1993

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Cyclin D1 overexpression in colorectal carcinoma in vivo is dependent on β-catenin protein dysregulation, but not k-ras mutation

The Journal of pathology, 2002-05, Vol.197 (1), p.128-135

2002

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A comparison of methods for limited-sampling strategy design using data from a phase I trial of the anthrapyrazole DuP-941

Cancer chemotherapy and pharmacology, 1996, Vol.37 (4), p.356-362

1996

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The effect of cimetidine on the pharmacokinetics of epirubicin in patients with advanced breast cancer: Preliminary evidence of a potentially common drug interaction

Clinical oncology (Royal College of Radiologists (Great Britain)), 1998, Vol.10 (1), p.35-38

1998

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A randomised comparative trial of mitozantrone/methotrexate/mitomycin C (MMM) and cyclophosphamide/methotrexate/5 FU (CMF) in the treatment of advanced breast cancer

British journal of cancer, 1991-05, Vol.63 (5), p.794-798

1991

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Modeling toxicity and response in carboplatin-based combination chemotherapy

Seminars in oncology, 1994-10, Vol.21 (5 Suppl 12), p.7

1994

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Carboplatin in the treatment of metastatic carcinoid tumours and paraganglioma : a phase II study

Cancer chemotherapy and pharmacology, 1990-01, Vol.26 (1), p.62-64

1990

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Forearm blood flow and local responses to peptide vasodilators : A novel pharmacodynamic measure in the Phase I trial of antagonist G, a neuropeptide growth factor antagonist

Clinical cancer research, 2001-10, Vol.7 (10), p.3071-3078

2001

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Tuning the Reactivity of Osmium(II) and Ruthenium(II) Arene Complexes under Physiological Conditions

Journal of the American Chemical Society, 2006-02, Vol.128 (5), p.1739-1748

2006

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Bolus/infusional 5-fluorouracil and folinic acid for metastatic colorectal carcinoma: are suboptimal dosages being used in the UK?

British journal of cancer, 1994-10, Vol.70 (4), p.749-752

1994

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Controlling Ligand Substitution Reactions of Organometallic Complexes: Tuning Cancer Cell Cytotoxicity

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (51), p.18269-18274

2005

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In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer

Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo

Phase II studies of BBR3464, a novel tri-nuclear platinum complex, in patients with gastric or gastro-oesophageal adenocarcinoma

Scheduling nab-paclitaxel combined with gemcitabine as first-line treatment for metastatic pancreatic adenocarcinoma

Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma

Relationships between carboplatin exposure and tumor response and toxicity in patients with ovarian cancer

Evaluation of rodent-only toxicology for early clinical trials with novel cancer therapeutics

5-fluorouracil steady state pharmacokinetics and outcome in patients receiving protracted venous infusion for advanced colorectal cancer

A phase I and pharmacological study of the matrix metalloproteinase inhibitor BB-3644 in patients with solid tumours

Population pharmacokinetics of gentamicin in patients with cancer

Platinum distribution in malignant glioma following intraoperative intravenous infusion of carboplatin

Identification of a region of frequent loss of heterozygosity at 11q24 in colorectal cancer

Dose-limiting neurotoxicity in a phase I study of penclomedine (NSC 388720, CRC 88-04), a synthetic α-picoline derivative, administered intravenously

Impact of cyclophosphamide on relationships between carboplatin exposure and response or toxicity when used in the treatment of advanced ovarian cancer

Cyclin D1 overexpression in colorectal carcinoma in vivo is dependent on β-catenin protein dysregulation, but not k-ras mutation

A comparison of methods for limited-sampling strategy design using data from a phase I trial of the anthrapyrazole DuP-941

The effect of cimetidine on the pharmacokinetics of epirubicin in patients with advanced breast cancer: Preliminary evidence of a potentially common drug interaction

A randomised comparative trial of mitozantrone/methotrexate/mitomycin C (MMM) and cyclophosphamide/methotrexate/5 FU (CMF) in the treatment of advanced breast cancer

Modeling toxicity and response in carboplatin-based combination chemotherapy

Carboplatin in the treatment of metastatic carcinoid tumours and paraganglioma : a phase II study

Forearm blood flow and local responses to peptide vasodilators : A novel pharmacodynamic measure in the Phase I trial of antagonist G, a neuropeptide growth factor antagonist

Tuning the Reactivity of Osmium(II) and Ruthenium(II) Arene Complexes under Physiological Conditions

Bolus/infusional 5-fluorouracil and folinic acid for metastatic colorectal carcinoma: are suboptimal dosages being used in the UK?

Controlling Ligand Substitution Reactions of Organometallic Complexes: Tuning Cancer Cell Cytotoxicity

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