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TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes

Journal of clinical oncology, 2020-12, Vol.38 (36), p.4274-4282

2020

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Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells

PloS one, 2012-10, Vol.7 (10), p.e46614

2012

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An open-label, pilot study of veliparib and lapatinib in patients with metastatic, triple-negative breast cancer

Breast cancer research : BCR, 2021-03, Vol.23 (1), p.30-12, Article 30

2021

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A phase I/II study of preoperative letrozole, everolimus, and carotuximab in stage 2 and 3 hormone receptor-positive and Her2-negative breast cancer

Breast cancer research and treatment, 2023-04, Vol.198 (2), p.217-229

2023

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The antitumor effects of entinostat in ovarian cancer require adaptive immunity

Cancer, 2018-12, Vol.124 (24), p.4657-4666

2018

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HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair

Cancer research (Chicago, Ill.), 2012-09, Vol.72 (18), p.4796-4806

2012

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Erlotinib attenuates homologous recombinational repair of chromosomal breaks in human breast cancer cells

Cancer research (Chicago, Ill.), 2008-11, Vol.68 (22), p.9141-9146

2008

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Molecular Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma

Molecular cancer research, 2018-05, Vol.16 (5), p.813-824

2018

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DNA Damage-Induced Cytotoxicity Is Dissociated from BRCA1's DNA Repair Function but Is Dependent on Its Cytosolic Accumulation

Cancer research (Chicago, Ill.), 2010-08, Vol.70 (15), p.6258-6267

2010

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Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets

PloS one, 2016-08, Vol.11 (8), p.e0160924-e0160924

2016

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Endoglin (CD105) Contributes to Platinum Resistance and Is A Target for Tumor-Specific Therapy in Epithelial Ovarian Cancer

Clinical cancer research, 2013-01, Vol.19 (1), p.170-182

2013

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Targeting BRCA1 Localization to Augment Breast Tumor Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

Cancer research (Chicago, Ill.), 2012-11, Vol.72 (21), p.5547-5555

2012

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CHK1/2 Inhibitor Prexasertib Suppresses NOTCH Signaling and Enhances Cytotoxicity of Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma

Molecular cancer therapeutics, 2020-06, Vol.19 (6), p.1279-1288

2020

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Randomized trial of weight loss in primary breast cancer: Impact on body composition, circulating biomarkers and tumor characteristics

International journal of cancer, 2020-05, Vol.146 (10), p.2784-2796

2020

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Inhibition of ribonucleotide reductase subunit M2 enhances the radiosensitivity of metastatic pancreatic neuroendocrine tumor

Cancer letters, 2024-08, Vol.596, p.216993, Article 216993

2024

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The BET inhibitor JQ1 attenuates double-strand break repair and sensitizes models of pancreatic ductal adenocarcinoma to PARP inhibitors

EBioMedicine, 2019-06, Vol.44, p.419-430

2019

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BRCA1 16 years later: DNA damage-induced BRCA1 shuttling

The FEBS journal, 2010-08, Vol.277 (15), p.3079-3085

2010

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DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma

Oncotarget, 2015-09, Vol.6 (29), p.26995-27007

2015

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Gene Expression Signature Correlates with Outcomes in Metastatic Renal Cell Carcinoma Patients Treated with Everolimus Alone or with a Vascular Disrupting Agent

Molecular cancer therapeutics, 2021-08, Vol.20 (8), p.1454-1461

2021

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Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors

Molecular cancer research, 2017-03, Vol.15 (3), p.340-347

2017

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Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

Oncotarget, 2016-12, Vol.7 (52), p.86803-86815

2016

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Notch Signaling Activation Is Associated with Patient Mortality and Increased FGF1-Mediated Invasion in Squamous Cell Carcinoma of the Oral Cavity

Molecular cancer research, 2016-09, Vol.14 (9), p.883-891

2016

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The protective effect of p16(INK4a) in oral cavity carcinomas: p16(Ink4A) dampens tumor invasion-integrated analysis of expression and kinomics pathways

Modern pathology, 2015-05, Vol.28 (5), p.631-653

2015

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Poly(N‑vinylpyrrolidone)-block-Poly(dimethylsiloxane)-block-Poly(N‑vinylpyrrolidone) Triblock Copolymer Polymersomes for Delivery of PARP1 siRNA to Breast Cancers

ACS applied bio materials, 2022-04, Vol.5 (4), p.1670-1682

2022

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WNT pathway signaling is associated with microvascular injury and predicts kidney transplant failure

American journal of transplantation, 2019-10, Vol.19 (10), p.2833-2845

2019

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TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes

Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells

An open-label, pilot study of veliparib and lapatinib in patients with metastatic, triple-negative breast cancer

A phase I/II study of preoperative letrozole, everolimus, and carotuximab in stage 2 and 3 hormone receptor-positive and Her2-negative breast cancer

The antitumor effects of entinostat in ovarian cancer require adaptive immunity

HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair

Erlotinib attenuates homologous recombinational repair of chromosomal breaks in human breast cancer cells

Molecular Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma

DNA Damage-Induced Cytotoxicity Is Dissociated from BRCA1's DNA Repair Function but Is Dependent on Its Cytosolic Accumulation

Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets

Endoglin (CD105) Contributes to Platinum Resistance and Is A Target for Tumor-Specific Therapy in Epithelial Ovarian Cancer

Targeting BRCA1 Localization to Augment Breast Tumor Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

CHK1/2 Inhibitor Prexasertib Suppresses NOTCH Signaling and Enhances Cytotoxicity of Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma

Randomized trial of weight loss in primary breast cancer: Impact on body composition, circulating biomarkers and tumor characteristics

Inhibition of ribonucleotide reductase subunit M2 enhances the radiosensitivity of metastatic pancreatic neuroendocrine tumor

The BET inhibitor JQ1 attenuates double-strand break repair and sensitizes models of pancreatic ductal adenocarcinoma to PARP inhibitors

BRCA1 16 years later: DNA damage-induced BRCA1 shuttling

DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma

Gene Expression Signature Correlates with Outcomes in Metastatic Renal Cell Carcinoma Patients Treated with Everolimus Alone or with a Vascular Disrupting Agent

Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors

Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

Notch Signaling Activation Is Associated with Patient Mortality and Increased FGF1-Mediated Invasion in Squamous Cell Carcinoma of the Oral Cavity

The protective effect of p16(INK4a) in oral cavity carcinomas: p16(Ink4A) dampens tumor invasion-integrated analysis of expression and kinomics pathways

Poly(N‑vinylpyrrolidone)-block-Poly(dimethylsiloxane)-block-Poly(N‑vinylpyrrolidone) Triblock Copolymer Polymersomes for Delivery of PARP1 siRNA to Breast Cancers

WNT pathway signaling is associated with microvascular injury and predicts kidney transplant failure

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