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Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

Cell proliferation, 2021-01, Vol.54 (1), p.e12941-n/a

2021

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Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (45), p.16148-16153

2014

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Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

Proceedings of the National Academy of Sciences - PNAS, 2003-11, Vol.100 (24), p.13940-13945

2003

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Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (16), p.6331-6336

2012

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Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

Nature (London), 2016-04, Vol.532 (7597), p.112-116

2016

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Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (32), p.13180-13185

2013

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Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (26), p.12980-12985

2019

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Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels

Nature communications, 2013, Vol.4 (1), p.1884-1884, Article 1884

2013

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A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins

The FASEB journal, 2012-12, Vol.26 (12), p.5141-5151

2012

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Ion Channel Functions in Early Brain Development

Trends in neurosciences (Regular ed.), 2020-02, Vol.43 (2), p.103-114

2020

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Chemical and Genetic Engineering of Selective Ion Channel—Ligand Interactions

Science (American Association for the Advancement of Science), 2011-09, Vol.333 (6047), p.1292-1296

2011

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PIEZO2 in sensory neurons and urothelial cells coordinates urination

Nature (London), 2020-12, Vol.588 (7837), p.290-295

2020

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Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target

Scientific reports, 2016-11, Vol.6 (1), p.37360-37360, Article 37360

2016

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Shear force modulates the activity of acid-sensing ion channels at low pH or in the presence of non-proton ligands

Scientific reports, 2019-05, Vol.9 (1), p.6781-6781, Article 6781

2019

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Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia

Nature communications, 2015-09, Vol.6 (1), p.8329-8329, Article 8329

2015

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A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

Neuron (Cambridge, Mass.), 2018-11, Vol.100 (4), p.799-815.e7

2018

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The Role of PIEZO2 in Human Mechanosensation

The New England journal of medicine, 2016-10, Vol.375 (14), p.1355-1364

2016

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Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride

Brain (London, England : 1878), 2013, Vol.136 (Pt 1), p.106-115

2013

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Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies

Physiological genomics, 2023-09, Vol.55 (9), p.357-367

2023

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Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia

Circulation (New York, N.Y.), 2007-07, Vol.116 (5), p.463-470

2007

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Placental ion channels: potential target of chemical exposure

Biology of reproduction, 2023-01, Vol.108 (1), p.41-51

2023

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Structural mechanisms of selectivity and gating in anion channelrhodopsins

Nature (London), 2018-09, Vol.561 (7723), p.349-354

2018

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Piezo1 channels are mechanosensors in human fetoplacental endothelial cells

Molecular human reproduction, 2018-10, Vol.24 (10), p.510-520

2018

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Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (27), p.9355-9360

2008

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Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis

Nature communications, 2023-04, Vol.14 (1), p.2479-2479, Article 2479

2023

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Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening

Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions

Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels

A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins

Ion Channel Functions in Early Brain Development

Chemical and Genetic Engineering of Selective Ion Channel—Ligand Interactions

PIEZO2 in sensory neurons and urothelial cells coordinates urination

Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target

Shear force modulates the activity of acid-sensing ion channels at low pH or in the presence of non-proton ligands

Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia

A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

The Role of PIEZO2 in Human Mechanosensation

Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride

Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies

Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia

Placental ion channels: potential target of chemical exposure

Structural mechanisms of selectivity and gating in anion channelrhodopsins

Piezo1 channels are mechanosensors in human fetoplacental endothelial cells

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis

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