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Dorothy Hodgkin Lecture 2014 Understanding genes identified by genome-wide association studies for Type 2 diabetes

Diabetic medicine, 2014-12, Vol.31 (12), p.1480-1487

Rutter, G. A.

2014

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Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

Diabetologia, 2010-08, Vol.53 (8), p.1656-1668

2010

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Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

Diabetologia, 2014-01, Vol.57 (1), p.122-128

2014

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Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

Diabetologia, 2012-10, Vol.55 (10), p.2667-2676

2012

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Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity

Diabetologia, 2007-01, Vol.50 (1), p.168-177

2007

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Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells

Diabetologia, 2004-09, Vol.47 (9), p.1592-1601

2004

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Visualising insulin secretion. The Minkowski Lecture 2004

Diabetologia, 2004-11, Vol.47 (11), p.1861-1872

RUTTER, G. A

2004

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AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells

Diabetologia, 2011-01, Vol.54 (1), p.125-134

2011

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Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

Diabetologia, 2011-04, Vol.54 (4), p.819-827

2011

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An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes

Diabetologia, 2011-12, Vol.54 (12), p.3078-3082

2011

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Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo

Journal of endocrinology, 2005-11, Vol.187 (2), p.225-235

2005

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Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion

Diabetes (New York, N.Y.), 2000-07, Vol.49 (7), p.1149-1155

2000

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When less is more: the forbidden fruits of gene repression in the adult β-cell

Diabetes, obesity & metabolism, 2013-06, Vol.15 (6), p.503-512

2013

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Intra-islet glucagon signalling regulates beta-cell connectivity, first-phase insulin secretion and glucose homoeostasis

Molecular metabolism (Germany), 2024-07, Vol.85, p.101947, Article 101947

2024

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Ablation of AMP-activated protein kinase alpha 1 and alpha 2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo

Diabetologia, 2010-05, Vol.53 (5), p.924-936

2010

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Pancreatic β-cell imaging in humans: fiction or option?

Diabetes, obesity & metabolism, 2016-01, Vol.18 (1), p.6-15

2016

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Expression and Distribution of Lactate/Monocarboxylate Transporter Isoforms in Pancreatic Islets and the Exocrine Pancreas

Diabetes (New York, N.Y.), 2001-02, Vol.50 (2), p.361-366

2001

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Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis

Diabetologia, 2006-07, Vol.49 (7), p.1567-1577

2006

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Expanding role of AMPK in endocrinology

Trends in endocrinology and metabolism, 2006-07, Vol.17 (5), p.205-215

2006

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Glucose or Insulin, but not Zinc Ions, Inhibit Glucagon Secretion From Mouse Pancreatic α-Cells

Diabetes (New York, N.Y.), 2005-06, Vol.54 (6), p.1789-1797

2005

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AMP-activated protein kinase: A new β-cell glucose sensor? Regulation by amino acids and calcium ions

Diabetes (New York, N.Y.), 2004-12, Vol.53 (12), p.67-74

2004

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Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion

American journal of physiology: endocrinology and metabolism, 2004-06, Vol.286 (6), p.E1023-E1031

2004

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Glucose-stimulated oscillations in free cytosolic ATP concentration imaged in single islet β-cells: Evidence for a Ca2+-dependent mechanism

Diabetes (New York, N.Y.), 2002-02, Vol.51, p.S162-S170

2002

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Sustained Exposure to High Glucose Concentrations Modifies Glucose Signaling and the Mechanics of Secretory Vesicle Fusion in Primary Rat Pancreatic β-Cells

Diabetes (New York, N.Y.), 2006-04, Vol.55 (4), p.1057-1065

2006

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Role for Plasma Membrane-Related Ca2+-ATPase-1 (ATP2C1) in Pancreatic β-Cell Ca2+ Homeostasis Revealed by RNA Silencing

Diabetes (New York, N.Y.), 2004-02, Vol.53 (2), p.393-400

2004

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Dorothy Hodgkin Lecture 2014 Understanding genes identified by genome-wide association studies for Type 2 diabetes

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells

Visualising insulin secretion. The Minkowski Lecture 2004

AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes

Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo

Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion

When less is more: the forbidden fruits of gene repression in the adult β-cell

Intra-islet glucagon signalling regulates beta-cell connectivity, first-phase insulin secretion and glucose homoeostasis

Ablation of AMP-activated protein kinase alpha 1 and alpha 2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo

Pancreatic β-cell imaging in humans: fiction or option?

Expression and Distribution of Lactate/Monocarboxylate Transporter Isoforms in Pancreatic Islets and the Exocrine Pancreas

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis

Expanding role of AMPK in endocrinology

Glucose or Insulin, but not Zinc Ions, Inhibit Glucagon Secretion From Mouse Pancreatic α-Cells

AMP-activated protein kinase: A new β-cell glucose sensor? Regulation by amino acids and calcium ions

Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion

Glucose-stimulated oscillations in free cytosolic ATP concentration imaged in single islet β-cells: Evidence for a Ca2+-dependent mechanism

Sustained Exposure to High Glucose Concentrations Modifies Glucose Signaling and the Mechanics of Secretory Vesicle Fusion in Primary Rat Pancreatic β-Cells

Role for Plasma Membrane-Related Ca2+-ATPase-1 (ATP2C1) in Pancreatic β-Cell Ca2+ Homeostasis Revealed by RNA Silencing

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