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Phase I and pharmacological trial of lapatinib in combination with gemcitabine in patients with advanced breast cancer

Investigational new drugs, 2015-12, Vol.33 (6), p.1197-1205

2015

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Exposure–response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients

Cancer chemotherapy and pharmacology, 2023-06, Vol.91 (6), p.447-456

2023

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Pharmacokinetically guided sunitinib dosing: a feasibility study in patients with advanced solid tumours

British journal of cancer, 2014-05, Vol.110 (10), p.2441-2449

2014

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The use of microtracers in food‐effect trials: An alternative study design for toxic drugs with long half‐lives exemplified by the case for alectinib

Clinical and translational science, 2023-12, Vol.16 (12), p.2557-2564

2023

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Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs

Clinical pharmacokinetics, 2023-08, Vol.62 (8), p.1157-1167

2023

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Methotrexate area under the curve is an important outcome predictor in patients with primary CNS lymphoma: A pharmacokinetic-pharmacodynamic analysis from the IELSG no. 20 trial

British journal of cancer, 2010-02, Vol.102 (4), p.673-677

2010

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A dose-escalation study of indisulam in combination with capecitabine (Xeloda) in patients with solid tumours

British journal of cancer, 2008-04, Vol.98 (8), p.1320-1326

2008

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Pilot Study to Predict Pharmacokinetics of a Therapeutic Gemcitabine Dose From a Microdose

Clinical pharmacology in drug development, 2020-11, Vol.9 (8), p.929-937

2020

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Integrated Simulation Framework for Toxicity, Dose Intensity, Disease Progression, and Cost Effectiveness for Castration‐Resistant Prostate Cancer Treatment With Eribulin

CPT: pharmacometrics and systems pharmacology, 2015-07, Vol.4 (7), p.374-385

2015

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Dosing of carboplatin in a patient with amputated legs: A case report

Journal of oncology pharmacy practice, 2014-12, Vol.20 (6), p.473-475

2014

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Therapeutic drug monitoring of oral targeted antineoplastic drugs

European journal of clinical pharmacology, 2021-04, Vol.77 (4), p.441-464

2021

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Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting

Pharmaceutical research, 2022-10, Vol.39 (10), p.2507-2514

2022

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Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine

European journal of clinical pharmacology, 2019-09, Vol.75 (9), p.1309-1318

2019

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Clinical Pharmacokinetics and Pharmacodynamics of Pazopanib: Towards Optimized Dosing

Clinical pharmacokinetics, 2017-09, Vol.56 (9), p.987-997

2017

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Pharmacokinetics and Pharmacodynamics of PARP Inhibitors in Oncology

Clinical pharmacokinetics, 2022-12, Vol.61 (12), p.1649-1675

2022

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Leishmania blood parasite dynamics during and after treatment of visceral leishmaniasis in Eastern Africa: A pharmacokinetic-pharmacodynamic model

PLoS neglected tropical diseases, 2024-04, Vol.18 (4), p.e0012078-e0012078

2024

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Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance

European journal of cancer (1990), 2022-03, Vol.164, p.137-154

2022

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Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Clinical pharmacokinetics, 2019-05, Vol.58 (5), p.627-637

2019

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Pharmacokinetics of PEGasparaginase in Infants with Acute Lymphoblastic Leukemia

Pharmaceutical research, 2024-04, Vol.41 (4), p.711-720

2024

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Harnessing soft tissue sarcoma with low-dose pazopanib - a matter of blood levels

BMC cancer, 2018-12, Vol.18 (1), p.1200-1200, Article 1200

2018

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Are novel oral oncolytics underdosed in obese patients?

Cancer chemotherapy and pharmacology, 2024-02, Vol.93 (2), p.129-136

2024

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Clinical Pharmacokinetics and Pharmacodynamics of the Cyclin-Dependent Kinase 4 and 6 Inhibitors Palbociclib, Ribociclib, and Abemaciclib

Clinical pharmacokinetics, 2020-12, Vol.59 (12), p.1501-1520

2020

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Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation

Clinical pharmacokinetics, 2020-06, Vol.59 (6), p.771-780

2020

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Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology

Clinical pharmacokinetics, 2023-10, Vol.62 (10), p.1333-1364

2023

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Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting

Supportive care in cancer, 2022-12, Vol.30 (12), p.9991-9999

2022

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Phase I and pharmacological trial of lapatinib in combination with gemcitabine in patients with advanced breast cancer

Exposure–response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients

Pharmacokinetically guided sunitinib dosing: a feasibility study in patients with advanced solid tumours

The use of microtracers in food‐effect trials: An alternative study design for toxic drugs with long half‐lives exemplified by the case for alectinib

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs

Methotrexate area under the curve is an important outcome predictor in patients with primary CNS lymphoma: A pharmacokinetic-pharmacodynamic analysis from the IELSG no. 20 trial

A dose-escalation study of indisulam in combination with capecitabine (Xeloda) in patients with solid tumours

Pilot Study to Predict Pharmacokinetics of a Therapeutic Gemcitabine Dose From a Microdose

Integrated Simulation Framework for Toxicity, Dose Intensity, Disease Progression, and Cost Effectiveness for Castration‐Resistant Prostate Cancer Treatment With Eribulin

Dosing of carboplatin in a patient with amputated legs: A case report

Therapeutic drug monitoring of oral targeted antineoplastic drugs

Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting

Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine

Clinical Pharmacokinetics and Pharmacodynamics of Pazopanib: Towards Optimized Dosing

Pharmacokinetics and Pharmacodynamics of PARP Inhibitors in Oncology

Leishmania blood parasite dynamics during and after treatment of visceral leishmaniasis in Eastern Africa: A pharmacokinetic-pharmacodynamic model

Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance

Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Pharmacokinetics of PEGasparaginase in Infants with Acute Lymphoblastic Leukemia

Harnessing soft tissue sarcoma with low-dose pazopanib - a matter of blood levels

Are novel oral oncolytics underdosed in obese patients?

Clinical Pharmacokinetics and Pharmacodynamics of the Cyclin-Dependent Kinase 4 and 6 Inhibitors Palbociclib, Ribociclib, and Abemaciclib

Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation

Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting

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