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Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector

Nature medicine, 1999-01, Vol.5 (1), p.56-63

1999

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Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

Nature medicine, 1999-01, Vol.5 (1), p.64-70

1999

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Extravascular administration of factor IX: potential for replacement therapy of canine and human hemophilia B

Thrombosis and haemostasis, 1997, Vol.77 (5), p.944-948

1997

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In Vivo Gene Therapy of Hemophilia B: Sustained Partial Correction in Factor IX-Deficient Dogs

Science (American Association for the Advancement of Science), 1993-10, Vol.262 (5130), p.117-119

1993

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In vivo Hepatic Gene Therapy: Complete Albeit Transient Correction of Factor IX Deficiency in Hemophilia B Dogs

Proceedings of the National Academy of Sciences - PNAS, 1994-03, Vol.91 (6), p.2353-2357

1994

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Pharmacokinetics of recombinant factor IX after intravenous and subcutaneous administration in dogs and cynomolgus monkeys

Thrombosis and haemostasis, 2002-05, Vol.87 (5), p.824-830

2002

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Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs

Gene therapy, 1996-03, Vol.3 (3), p.217

1996

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Preservation of Hemostatic and Structural Properties of Rehydrated Lyophilized Platelets: Potential for Long-Term Storage of Dried Platelets for Transfusion

Proceedings of the National Academy of Sciences - PNAS, 1995-01, Vol.92 (2), p.397-401

1995

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Canine Hemophilia B Resulting from a Point Mutation with Unusual Consequences

Proceedings of the National Academy of Sciences - PNAS, 1989-12, Vol.86 (24), p.10095-10099

1989

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Gene therapy for hemophilia B: host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression

Human gene therapy, 1995-08, Vol.6 (8), p.1039-1044

1995

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Replacing the first epidermal growth factor-like domain of factor IX with that of factor VII enhances activity in vitro and in canine hemophilia B

The Journal of clinical investigation, 1997-08, Vol.100 (4), p.886-892

1997

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Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogs

Proceedings of the National Academy of Sciences - PNAS, 1990-07, Vol.87 (13), p.5173-5177

1990

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Thrombotic thrombocytopenia induced in dogs and pigs. The role of plasma and platelet vWF in animal models of thrombotic thrombocytopenic purpura

Arteriosclerosis, thrombosis, and vascular biology, 1995-06, Vol.15 (6), p.793-800

1995

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The Roles of von Willebrand Factor and Factor VIII in Arterial Thrombosis: Studies in Canine von Willebrand Disease and Hemophilia A

Blood, 1993-05, Vol.81 (10), p.2644-2651

1993

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Gene transfer in the hemophilias: Retrospect and prospect

Thrombosis research, 1992-08, Vol.67 (3), p.329-338

Brinkhous, Kenneth M.

1992

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Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes

Human gene therapy, 1994-03, Vol.5 (3), p.313-322

1994

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Von Willebrand Syndrome Induced by a Bothrops Venom Factor: Bioassay for Venom Coagglutinin

Proceedings of the National Academy of Sciences - PNAS, 1981-05, Vol.78 (5), p.3230-3234

1981

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Expression and Linkage of Genes for X-linked Hemophilias A and B in the Dog

Blood, 1973-04, Vol.41 (4), p.577-585

1973

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PLASMA THROMBOCYTE-AGGLUTINATING ACTIVITY AND FIBRINOGEN. SYNERGISM WITH ADENOSINE DIPHOSPHATE

Laboratory investigation, 1965-04, Vol.14, p.335

1965

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Hemophilia in the Female Dog

Science (American Association for the Advancement of Science), 1950-06, Vol.111 (2896), p.723-724

1950

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Scanning electron microscopy of synovial membranes

Archives of pathology (1960), 1972-02, Vol.93 (2), p.172

1972

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Studies on thrombin-induced platelet agglutination

The Journal of experimental medicine, 1961-12, Vol.114 (6), p.905-920

1961

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Platelet agglutination and deagglutination with a sulfhydryl inhibitor, methyl mercuric nitrate: Relationships to platelet ATPase

Experimental and molecular pathology, 1965-10, Vol.4 (5), p.457-464

1965

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CANINE HEMOPHILIA AND MALE PSEUDOHERMAPHRODITISM; CYTOGENETIC STUDIES

Laboratory investigation, 1963-10, Vol.12, p.961

1963

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Species differences in platelet agglutination in man and in the dog, swine and rabbit

The American journal of physiology, 1960-07, Vol.199 (1), p.183-186

1960

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Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

Extravascular administration of factor IX: potential for replacement therapy of canine and human hemophilia B

In Vivo Gene Therapy of Hemophilia B: Sustained Partial Correction in Factor IX-Deficient Dogs

In vivo Hepatic Gene Therapy: Complete Albeit Transient Correction of Factor IX Deficiency in Hemophilia B Dogs

Pharmacokinetics of recombinant factor IX after intravenous and subcutaneous administration in dogs and cynomolgus monkeys

Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs

Preservation of Hemostatic and Structural Properties of Rehydrated Lyophilized Platelets: Potential for Long-Term Storage of Dried Platelets for Transfusion

Canine Hemophilia B Resulting from a Point Mutation with Unusual Consequences

Gene therapy for hemophilia B: host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression

Replacing the first epidermal growth factor-like domain of factor IX with that of factor VII enhances activity in vitro and in canine hemophilia B

Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogs

Thrombotic thrombocytopenia induced in dogs and pigs. The role of plasma and platelet vWF in animal models of thrombotic thrombocytopenic purpura

The Roles of von Willebrand Factor and Factor VIII in Arterial Thrombosis: Studies in Canine von Willebrand Disease and Hemophilia A

Gene transfer in the hemophilias: Retrospect and prospect

Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes

Von Willebrand Syndrome Induced by a Bothrops Venom Factor: Bioassay for Venom Coagglutinin

Expression and Linkage of Genes for X-linked Hemophilias A and B in the Dog

PLASMA THROMBOCYTE-AGGLUTINATING ACTIVITY AND FIBRINOGEN. SYNERGISM WITH ADENOSINE DIPHOSPHATE

Hemophilia in the Female Dog

Scanning electron microscopy of synovial membranes

Studies on thrombin-induced platelet agglutination

Platelet agglutination and deagglutination with a sulfhydryl inhibitor, methyl mercuric nitrate: Relationships to platelet ATPase

CANINE HEMOPHILIA AND MALE PSEUDOHERMAPHRODITISM; CYTOGENETIC STUDIES

Species differences in platelet agglutination in man and in the dog, swine and rabbit

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