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Targeting DNA damage and repair: embracing the pharmacological era for successful cancer therapy

Pharmacology & therapeutics (Oxford), 2012-03, Vol.133 (3), p.334-350

2012

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Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity

Scientific reports, 2017-02, Vol.7 (1), p.42700-42700, Article 42700

2017

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Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams

Scientific reports, 2016-08, Vol.6 (1), p.32441-32441, Article 32441

2016

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Mechanisms of DNA double strand break repair and chromosome aberration formation

Cytogenetic and Genome Research, 2004-01, Vol.104 (1-4), p.14-20

2004

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Cell cycle regulation in irradiated and nonirradiated cells

Seminars in oncology, 1997-12, Vol.24 (6), p.602-615

Iliakis, G

1997

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Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants

Oncogene, 2000-11, Vol.19 (50), p.5788-5800

2000

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Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells

Science (American Association for the Advancement of Science), 2014-01, Vol.343 (6166), p.88-91

2014

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DNA damage checkpoint control in cells exposed to ionizing radiation

Oncogene, 2003-09, Vol.22 (37), p.5834-5847

2003

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DNA ligase III as a candidate component of backup pathways of nonhomologous end joining

Cancer research (Chicago, Ill.), 2005-05, Vol.65 (10), p.4020-4030

2005

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Computational Methods for Analysis of Foci: Validation for Radiation-Induced γ-H2AX Foci in Human Cells

Radiation research, 2006-01, Vol.165 (1), p.113-124

2006

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The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells

BioEssays, 1991-12, Vol.13 (12), p.641-648

Iliakis, G

1991

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Homology-Directed Repair is Required for the Development of Radioresistance during S Phase: Interplay between Double-Strand Break Repair and Checkpoint Response

Radiation research, 2007-01, Vol.167 (1), p.1-11

2007

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Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines

Radiation research, 1995-10, Vol.144 (1), p.26

1995

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Biochemical evidence for Ku-independent backup pathways of NHEJ

Nucleic acids research, 2003-09, Vol.31 (18), p.5377-5388

2003

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ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining

Cancer research (Chicago, Ill.), 2004-10, Vol.64 (19), p.7139-7143

2004

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hTERT associates with human telomeres and enhances genomic stability and DNA repair

Oncogene, 2003-01, Vol.22 (1), p.131-146

2003

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Detection of DNA Double-strand Breaks in Synchronous Cultures of CHO Cells by Means of Asymmetric Field Inversion Gel Electrophoresis

International journal of radiation biology, 1991, Vol.59 (2), p.321-341

1991

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RPA facilitates rejoining of DNA double-strand breaks in an in vitro assay utilizing genomic DNA as substrate

International journal of radiation biology, 2001, Vol.77 (5), p.593-607

Perrault, Nge Cheong, Huichen Wang, Hongyan Wang, G. Iliakis, R.

2001

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In vitro rejoining of DNA double strand breaks: a comparison of genomic-DNA with plasmid-DNA-based assays

International journal of radiation biology, 1998-05, Vol.73 (5), p.481-493

1998

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Rejoining of DNA double-strand breaks in Ku80-deficient mouse fibroblasts

Radiation research, 1999-04, Vol.151 (4), p.398

1999

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In vitro rejoining of double strand breaks induced in cellular DNA by bleomycin and restriction endonucleases

International journal of radiation biology, 1997-04, Vol.71 (4), p.365-375

ILIAKIS, N. CHEONG and G.

1997

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DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus

Cancer research (Chicago, Ill.), 2000-03, Vol.60 (5), p.1245-1253

2000

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In vitro rejoining of double-strand breaks in genomic DNA

Methods in molecular biology (Clifton, N.J.), 1999, Vol.113, p.473

1999

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Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group

Oncogene, 2001-04, Vol.20 (18), p.2212-2224

2001

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Radiosensitivity Throughout the Cell Cycle and Repair of Potentially Lethal Damage and DNA Double-strand Breaks in an X-ray-sensitive CHO Mutant

International journal of radiation biology, 1990, Vol.57 (6), p.1195-1211

1990

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Targeting DNA damage and repair: embracing the pharmacological era for successful cancer therapy

Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity

Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams

Mechanisms of DNA double strand break repair and chromosome aberration formation

Cell cycle regulation in irradiated and nonirradiated cells

Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants

Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells

DNA damage checkpoint control in cells exposed to ionizing radiation

DNA ligase III as a candidate component of backup pathways of nonhomologous end joining

Computational Methods for Analysis of Foci: Validation for Radiation-Induced γ-H2AX Foci in Human Cells

The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells

Homology-Directed Repair is Required for the Development of Radioresistance during S Phase: Interplay between Double-Strand Break Repair and Checkpoint Response

Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines

Biochemical evidence for Ku-independent backup pathways of NHEJ

ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining

hTERT associates with human telomeres and enhances genomic stability and DNA repair

Detection of DNA Double-strand Breaks in Synchronous Cultures of CHO Cells by Means of Asymmetric Field Inversion Gel Electrophoresis

RPA facilitates rejoining of DNA double-strand breaks in an in vitro assay utilizing genomic DNA as substrate

In vitro rejoining of DNA double strand breaks: a comparison of genomic-DNA with plasmid-DNA-based assays

Rejoining of DNA double-strand breaks in Ku80-deficient mouse fibroblasts

In vitro rejoining of double strand breaks induced in cellular DNA by bleomycin and restriction endonucleases

DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus

In vitro rejoining of double-strand breaks in genomic DNA

Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group

Radiosensitivity Throughout the Cell Cycle and Repair of Potentially Lethal Damage and DNA Double-strand Breaks in an X-ray-sensitive CHO Mutant

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