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Stabilization of human telomeric RNA G-quadruplex by the water-compatible optically pure and biologically-active metallohelices

Scientific reports, 2020-09, Vol.10 (1), p.14543-14543, Article 14543

2020

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Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles

Nucleic acids research, 2022-01, Vol.50 (2), p.674-683

2022

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Asymmetric triplex metallohelices stabilise DNA G-quadruplexes in promoter oncogene sequences and efficiently reduce their expression in cancer cells

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2198678-2198678

2023

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Photo-induced DNA cleavage and cytotoxicity of a ruthenium(II) arene anticancer complex

Journal of inorganic biochemistry, 2016-07, Vol.160, p.149-155

2016

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Recognition of DNA/RNA bulges by antimicrobial and antitumor metallohelices

Dalton transactions : an international journal of inorganic chemistry, 2015-09, Vol.44 (33), p.14656-14665

2015

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Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1

Nucleic acids research, 2015-06, Vol.43 (11), p.5297-5306

2015

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A Potent Cytotoxic Photoactivated Platinum Complex

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (52), p.20743-20748

2007

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Antiproliferative, DNA binding, and cleavage properties of dinuclear Co(III) complexes containing the bioactive quinizarin ligand

Journal of biological inorganic chemistry, 2020-03, Vol.25 (2), p.339-350

2020

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Optically pure, water-stable metallo-helical 'flexicate' assemblies with antibiotic activity

Nature chemistry, 2012-01, Vol.4 (1), p.31-36

2012

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DNA Interactions of Monofunctional Organometallic Ruthenium(II) Antitumor Complexes in Cell-free Media

Biochemistry (Easton), 2003-10, Vol.42 (39), p.11544-11554

2003

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Induced-Fit Recognition of DNA by Organometallic Complexes with Dynamic Stereogenic Centers

Proceedings of the National Academy of Sciences - PNAS, 2003-12, Vol.100 (25), p.14623-14628

2003

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Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs

Inorganic chemistry, 2018-11, Vol.57 (22), p.14409-14420

2018

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Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts

Chemistry : a European journal, 2013-07, Vol.19 (29), p.9578-9591

2013

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Dual Triggering of DNA Binding and Fluorescence via Photoactivation of a Dinuclear Ruthenium(II) Arene Complex

Inorganic chemistry, 2007-06, Vol.46 (12), p.5059-5068

2007

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Bifunctional Amine-Tethered Ruthenium(II) Arene Complexes Form Monofunctional Adducts on DNA

Inorganic chemistry, 2007-10, Vol.46 (21), p.8950-8962

2007

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Functionalization of Osmium Arene Anticancer Complexes with (Poly)arginine: Effect on Cellular Uptake, Internalization, and Cytotoxicity

Bioconjugate chemistry, 2011-02, Vol.22 (2), p.218-226

2011

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"Head-to-head" double-hamburger-like structure of di-ruthenated d(GpG) adducts of mono-functional Ru-arene anticancer complexes

Dalton transactions : an international journal of inorganic chemistry, 2016-11, Vol.45 (46), p.18676-18688

2016

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Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds

European journal of pharmaceutical sciences, 2015-08, Vol.76, p.192-202

2015

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3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents

European journal of medicinal chemistry, 2012-11, Vol.57, p.283-295

2012

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Combined Theoretical and Computational Study of Interstrand DNA Guanine–Guanine Cross-Linking by trans-[Pt(pyridine)2] Derived from the Photoactivated Prodrug trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2]

Inorganic chemistry, 2012-06, Vol.51 (12), p.6830-6841

2012

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DNA Interactions of Monofunctional Organometallic Osmium(II) Antitumor Complexes in Cell-Free Media

Journal of medicinal chemistry, 2008-06, Vol.51 (12), p.3635-3643

2008

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Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N 3) 2(OH) 2(NH 3)(L)]

Journal of inorganic biochemistry, 2011-05, Vol.105 (5), p.652-662

2011

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Novel trisubstituted acridines as human telomeric quadruplex binding ligands

Bioorganic chemistry, 2014-12, Vol.57, p.13-29

2014

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Cytotoxicity, Cellular Uptake, and DNA Interactions of New Monodentate Ruthenium(II) Complexes Containing Terphenyl Arenes

Journal of medicinal chemistry, 2008-09, Vol.51 (17), p.5310-5319

2008

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Energetics, conformation, and recognition of DNA duplexes modified by monodentate Ru(II) complexes containing terphenyl arenes

Chemistry : a European journal, 2010-05, Vol.16 (19), p.5744-5754

2010

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Stabilization of human telomeric RNA G-quadruplex by the water-compatible optically pure and biologically-active metallohelices

Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles

Asymmetric triplex metallohelices stabilise DNA G-quadruplexes in promoter oncogene sequences and efficiently reduce their expression in cancer cells

Photo-induced DNA cleavage and cytotoxicity of a ruthenium(II) arene anticancer complex

Recognition of DNA/RNA bulges by antimicrobial and antitumor metallohelices

Shape-selective recognition of DNA abasic sites by metallohelices: inhibition of human AP endonuclease 1

A Potent Cytotoxic Photoactivated Platinum Complex

Antiproliferative, DNA binding, and cleavage properties of dinuclear Co(III) complexes containing the bioactive quinizarin ligand

Optically pure, water-stable metallo-helical 'flexicate' assemblies with antibiotic activity

DNA Interactions of Monofunctional Organometallic Ruthenium(II) Antitumor Complexes in Cell-free Media

Induced-Fit Recognition of DNA by Organometallic Complexes with Dynamic Stereogenic Centers

Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs

Diazido Mixed-Amine Platinum(IV) Anticancer Complexes Activatable by Visible-Light Form Novel DNA Adducts

Dual Triggering of DNA Binding and Fluorescence via Photoactivation of a Dinuclear Ruthenium(II) Arene Complex

Bifunctional Amine-Tethered Ruthenium(II) Arene Complexes Form Monofunctional Adducts on DNA

Functionalization of Osmium Arene Anticancer Complexes with (Poly)arginine: Effect on Cellular Uptake, Internalization, and Cytotoxicity

"Head-to-head" double-hamburger-like structure of di-ruthenated d(GpG) adducts of mono-functional Ru-arene anticancer complexes

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds

3,6-Bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents

Combined Theoretical and Computational Study of Interstrand DNA Guanine–Guanine Cross-Linking by trans-[Pt(pyridine)2] Derived from the Photoactivated Prodrug trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2]

DNA Interactions of Monofunctional Organometallic Osmium(II) Antitumor Complexes in Cell-Free Media

Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N 3) 2(OH) 2(NH 3)(L)]

Novel trisubstituted acridines as human telomeric quadruplex binding ligands

Cytotoxicity, Cellular Uptake, and DNA Interactions of New Monodentate Ruthenium(II) Complexes Containing Terphenyl Arenes

Energetics, conformation, and recognition of DNA duplexes modified by monodentate Ru(II) complexes containing terphenyl arenes

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