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Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase

Science (American Association for the Advancement of Science), 2012-03, Vol.335 (6072), p.1110-1114

2012

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Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain

The FEBS journal, 2020-06, Vol.287 (11), p.2235-2255

2020

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Crystal Structures of the SpoIID Lytic Transglycosylases Essential for Bacterial Sporulation

The Journal of biological chemistry, 2016-07, Vol.291 (29), p.14915-14926

2016

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A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity

The Journal of biological chemistry, 2015-02, Vol.290 (9), p.5893-5911

2015

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Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase)

Bioorganic & medicinal chemistry, 2016-10, Vol.24 (19), p.4536-4543

2016

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The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron

Journal of biological inorganic chemistry, 2020-06, Vol.25 (4), p.571-582

2020

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Structural characterization and functional analysis of cystathionine β‐synthase: an enzyme involved in the reverse transsulfuration pathway of Bacillus anthracis

The FEBS journal, 2017-11, Vol.284 (22), p.3862-3880

2017

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Two Putative Polysaccharide Deacetylases Are Required for Osmotic Stability and Cell Shape Maintenance in Bacillus anthracis

The Journal of biological chemistry, 2015-05, Vol.290 (21), p.13465-13478

2015

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Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors

Biochemistry (Easton), 2016-10, Vol.55 (39), p.5587-5594

2016

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Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis

Biochemistry (Easton), 2015-05, Vol.54 (20), p.3197-3206

2015

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Structure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan Recognition

Structure (London), 2014-07, Vol.22 (7), p.949-960

2014

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Structure of the Bacillus anthracis dTDP-l-rhamnose biosynthetic pathway enzyme: dTDP-α-d-glucose 4,6-dehydratase, RfbB

Journal of structural biology, 2018-05, Vol.202 (2), p.175-181

2018

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Probing the ligand preferences of the three types of bacterial pantothenate kinase

Bioorganic & medicinal chemistry, 2018-12, Vol.26 (22), p.5896-5902

2018

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Bacillus anthracis Prolyl 4-Hydroxylase Modifies Collagen-like Substrates in Asymmetric Patterns

The Journal of biological chemistry, 2016-06, Vol.291 (25), p.13360-13374

2016

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Structural analysis of cofactor binding for a prolyl 4-hydroxylase from the pathogenic bacterium Bacillus anthracis

Acta crystallographica. Section D, Structural biology, 2016-05, Vol.72 (5), p.675-681

2016

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Essential Role of an Active-Site Guanine in glmS Ribozyme Catalysis

Journal of the American Chemical Society, 2007-12, Vol.129 (48), p.14858-14859

2007

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Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin

Nature (London), 2002-01, Vol.415 (6870), p.396-402

2002

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Elucidation of the bicarbonate binding site and insights into the carboxylation mechanism of (N5)-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis

Acta crystallographica. Section D, Biological crystallography., 2014-11, Vol.70 (11), p.3057-3065

2014

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The anthrax lethal factor and its MAPK kinase-specific metalloprotease activity

Molecular aspects of medicine, 2009-12, Vol.30 (6), p.431-438

2009

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Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis

Journal of molecular biology, 2012-07, Vol.420 (4-5), p.366-383

2012

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Structures of bacterial kynurenine formamidase reveal a crowded binuclear zinc catalytic site primed to generate a potent nucleophile

Biochemical journal, 2014-09, Vol.462 (3), p.581-589

2014

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Identification and Characterization of an Allosteric Inhibitory Site on Dihydropteroate Synthase

ACS chemical biology, 2014-06, Vol.9 (6), p.1294-1302

2014

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The putative polysaccharide deacetylase Ba0331: cloning, expression, crystallization and structure determination

Acta crystallographica. Section F, Structural biology communications, 2019-04, Vol.75 (4), p.312-320

2019

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Structure–activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase

Biochimica et biophysica acta, 2013-01, Vol.1834 (1), p.46-52

2013

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Structure of the Bacillus anthracis dTDP‐l‐rhamnose‐biosynthetic enzyme dTDP‐4‐dehydrorhamnose 3,5‐epimerase (RfbC)

Acta crystallographica. Section F, Structural biology communications, 2017-12, Vol.73 (12), p.664-671

2017

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Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase

Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain

Crystal Structures of the SpoIID Lytic Transglycosylases Essential for Bacterial Sporulation

A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity

Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase)

The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron

Structural characterization and functional analysis of cystathionine β‐synthase: an enzyme involved in the reverse transsulfuration pathway of Bacillus anthracis

Two Putative Polysaccharide Deacetylases Are Required for Osmotic Stability and Cell Shape Maintenance in Bacillus anthracis

Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors

Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis

Structure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan Recognition

Structure of the Bacillus anthracis dTDP-l-rhamnose biosynthetic pathway enzyme: dTDP-α-d-glucose 4,6-dehydratase, RfbB

Probing the ligand preferences of the three types of bacterial pantothenate kinase

Bacillus anthracis Prolyl 4-Hydroxylase Modifies Collagen-like Substrates in Asymmetric Patterns

Structural analysis of cofactor binding for a prolyl 4-hydroxylase from the pathogenic bacterium Bacillus anthracis

Essential Role of an Active-Site Guanine in glmS Ribozyme Catalysis

Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin

Elucidation of the bicarbonate binding site and insights into the carboxylation mechanism of (N5)-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis

The anthrax lethal factor and its MAPK kinase-specific metalloprotease activity

Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis

Structures of bacterial kynurenine formamidase reveal a crowded binuclear zinc catalytic site primed to generate a potent nucleophile

Identification and Characterization of an Allosteric Inhibitory Site on Dihydropteroate Synthase

The putative polysaccharide deacetylase Ba0331: cloning, expression, crystallization and structure determination

Structure–activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase

Structure of the Bacillus anthracis dTDP‐l‐rhamnose‐biosynthetic enzyme dTDP‐4‐dehydrorhamnose 3,5‐epimerase (RfbC)

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