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A time- and cost-efficient system for high-level protein production in mammalian cells

Acta crystallographica. Section D, Biological crystallography., 2006-10, Vol.62 (10), p.1243-1250

2006

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Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan

eLife, 2015-07, Vol.4

2015

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Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

Nature structural & molecular biology, 2012-12, Vol.19 (12), p.1293-1299

2012

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Structural and Functional Studies of LRP6 Ectodomain Reveal a Platform for Wnt Signaling

Developmental cell, 2011-11, Vol.21 (5), p.848-861

2011

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Structural Insights into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1

Structure (London), 2014-04, Vol.22 (4), p.612-620

2014

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Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight into Ternary Complex Formation with LRP6 and Dickkopf

Structure (London), 2016-09, Vol.24 (9), p.1599-1605

2016

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Structurally encoded intraclass differences in EphA clusters drive distinct cell responses

Nature structural & molecular biology, 2013-08, Vol.20 (8), p.958-964

2013

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Structural basis of fibrillar collagen trimerization and related genetic disorders

Nature structural & molecular biology, 2012-10, Vol.19 (10), p.1031-1036

2012

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Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning

Nature communications, 2019-08, Vol.10 (1), p.3691-12, Article 3691

2019

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A dual binding mode for RhoGTPases in plexin signalling

PLoS biology, 2011-08, Vol.9 (8), p.e1001134

2011

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Rational development of high-affinity T-cell receptor-like antibodies

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (14), p.5784-5788

2009

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The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

The Journal of biological chemistry, 2011-03, Vol.286 (12), p.10530-10539

2011

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Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis

Journal of the American Chemical Society, 2012-10, Vol.134 (42), p.17554-17563

2012

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A functional and structural basis for TCR cross-reactivity in multiple sclerosis

Nature immunology, 2002-10, Vol.3 (10), p.940-943

2002

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Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (50), p.E3483-E3492

2012

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Crystal structure of R-spondin 2 in complex with the ectodomains of its receptors LGR5 and ZNRF3

Journal of structural biology, 2015-08, Vol.191 (2), p.149-155

2015

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Initiation of T cell signaling by CD45 segregation at 'close contacts'

Nature immunology, 2016-05, Vol.17 (5), p.574-582

2016

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Crystal Structure of HLA-DQ0602 That Protects against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (7), p.1999-2004

2004

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Carbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions

Journal of molecular biology, 2009-04, Vol.387 (5), p.1061-1066

2009

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Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension

Science (American Association for the Advancement of Science), 2011-04, Vol.332 (6028), p.484-488

2011

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The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D

Nature structural & molecular biology, 2003-10, Vol.10 (10), p.843-848

2003

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Understanding cell signalling systems: paving the way for new therapies

Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences, 2015-03, Vol.373 (2036), p.20130155

Jones, E. Yvonne

2015

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Drosophila OTK Is a Glycosaminoglycan-Binding Protein with High Conformational Flexibility

Structure (London), 2020-05, Vol.28 (5), p.507-515.e5

2020

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Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.562-578

2022

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Mona/Gads SH3C Binding to Hematopoietic Progenitor Kinase 1 (HPK1) Combines an Atypical SH3 Binding Motif, R/KXXK, with a Classical PXXP Motif Embedded in a Polyproline Type II (PPII) Helix

The Journal of biological chemistry, 2004-07, Vol.279 (27), p.28724-28732

2004

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A time- and cost-efficient system for high-level protein production in mammalian cells

Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

Structural and Functional Studies of LRP6 Ectodomain Reveal a Platform for Wnt Signaling

Structural Insights into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1

Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight into Ternary Complex Formation with LRP6 and Dickkopf

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses

Structural basis of fibrillar collagen trimerization and related genetic disorders

Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning

A dual binding mode for RhoGTPases in plexin signalling

Rational development of high-affinity T-cell receptor-like antibodies

The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis

A functional and structural basis for TCR cross-reactivity in multiple sclerosis

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms

Crystal structure of R-spondin 2 in complex with the ectodomains of its receptors LGR5 and ZNRF3

Initiation of T cell signaling by CD45 segregation at 'close contacts'

Crystal Structure of HLA-DQ0602 That Protects against Type 1 Diabetes and Confers Strong Susceptibility to Narcolepsy

Carbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions

Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension

The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D

Understanding cell signalling systems: paving the way for new therapies

Drosophila OTK Is a Glycosaminoglycan-Binding Protein with High Conformational Flexibility

Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity

Mona/Gads SH3C Binding to Hematopoietic Progenitor Kinase 1 (HPK1) Combines an Atypical SH3 Binding Motif, R/KXXK, with a Classical PXXP Motif Embedded in a Polyproline Type II (PPII) Helix

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