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Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

Nature genetics, 2014-10, Vol.46 (10), p.1135-1139

2014

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SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP

Nature communications, 2022-08, Vol.13 (1), p.4788-4788, Article 4788

2022

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Autoregulation of the LIM kinases by their PDZ domain

Nature communications, 2023-12, Vol.14 (1), p.8441-8441, Article 8441

2023

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p190RhoGAP proteins contain pseudoGTPase domains

Nature communications, 2017-09, Vol.8 (1), p.506-9, Article 506

2017

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Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide

PloS one, 2019-12, Vol.14 (12), p.e0226113

2019

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Correction: Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide

PloS one, 2020-02, Vol.15 (2), p.e0229627-e0229627

2020

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Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (40), p.16107-16112

2012

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C-Cadherin Ectodomain Structure and Implications for Cell Adhesion Mechanisms

Science (American Association for the Advancement of Science), 2002-05, Vol.296 (5571), p.1308-1313

2002

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The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization

The Journal of biological chemistry, 2018-02, Vol.293 (5), p.1642-1650

2018

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CDC42 binds PAK4 via an extended GTPase-effector interface

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (3), p.531-536

2018

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The use of structural biology in Janus kinase targeted drug discovery

Current drug targets, 2011-04, Vol.12 (4), p.546-555

2011

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structural basis of integrin-linked kinase-PINCH interactions

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (52), p.20677-20682

2008

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ARGuing for a new kinase class

Nature chemical biology, 2019-05, Vol.15 (5), p.431-432

Boggon, Titus J

2019

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Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6

PloS one, 2013-10, Vol.8 (10), p.e77818-e77818

2013

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Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex

PloS one, 2013-01, Vol.8 (1), p.e55591-e55591

2013

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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

Nature genetics, 2012-09, Vol.44 (9), p.1006-1014

2012

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The N-Terminal GTPase Domain of p190RhoGAP Proteins Is a PseudoGTPase

Structure (London), 2018-11, Vol.26 (11), p.1451-1461.e4

2018

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PAK4 crystal structures suggest unusual kinase conformational movements

Biochimica et biophysica acta. Proteins and proteomics, 2018-02, Vol.1866 (2), p.356-365

2018

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Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase

Journal of structural biology, 2010-04, Vol.170 (1), p.157-163

2010

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Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD–FERM interface

Journal of structural biology, 2015-12, Vol.192 (3), p.449-456

2015

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Crystal Structure of CCM3, a Cerebral Cavernous Malformation Protein Critical for Vascular Integrity

The Journal of biological chemistry, 2010-07, Vol.285 (31), p.24099-24107

2010

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Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations

The Journal of biological chemistry, 2015-01, Vol.290 (5), p.2842-2853

2015

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Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220)

PloS one, 2015-04, Vol.10 (4), p.e0121177-e0121177

2015

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Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrate

PloS one, 2014-07, Vol.9 (7), p.e103518-e103518

2014

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Crystal structure and biochemical analysis of acetylesterase (LgEstI) from Lactococcus garvieae

PloS one, 2023-02, Vol.18 (2), p.e0280988-e0280988

2023

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Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP

Autoregulation of the LIM kinases by their PDZ domain

p190RhoGAP proteins contain pseudoGTPase domains

Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide

Correction: Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide

Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate

C-Cadherin Ectodomain Structure and Implications for Cell Adhesion Mechanisms

The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization

CDC42 binds PAK4 via an extended GTPase-effector interface

The use of structural biology in Janus kinase targeted drug discovery

structural basis of integrin-linked kinase-PINCH interactions

ARGuing for a new kinase class

Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6

Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

The N-Terminal GTPase Domain of p190RhoGAP Proteins Is a PseudoGTPase

PAK4 crystal structures suggest unusual kinase conformational movements

Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase

Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD–FERM interface

Crystal Structure of CCM3, a Cerebral Cavernous Malformation Protein Critical for Vascular Integrity

Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations

Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220)

Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrate

Crystal structure and biochemical analysis of acetylesterase (LgEstI) from Lactococcus garvieae

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